(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Win
Definition:
(a.) To gain by superiority in competition or contest; to obtain by victory over competitors or rivals; as, to win the prize in a gate; to win money; to win a battle, or to win a country.
(a.) To allure to kindness; to bring to compliance; to gain or obtain, as by solicitation or courtship.
(a.) To gain over to one's side or party; to obtain the favor, friendship, or support of; to render friendly or approving; as, to win an enemy; to win a jury.
(a.) To come to by toil or effort; to reach; to overtake.
(a.) To extract, as ore or coal.
(v. i.) To gain the victory; to be successful; to triumph; to prevail.
Example Sentences:
(1) He was the first to win as a captain and a manager.
(2) We knew it would be a strange match because they had to come out and play to win to finish third,” Benitez said afterwards.
(3) Johnson and Campion are optimistic that marriage equality will win out, and soon.
(4) Spotlight is still the favourite to win best picture A dinner in Beverly Hills was hosted in Spotlight’s honor on Sunday night.
(5) As James said in Friday’s announcement, his goal was to win championships, and in Miami he was able to reach the NBA Finals every year.
(6) We are deeply saddened," said Nyan Win, a spokesman of National League for Democracy.
(7) Two years later, Trump tweeted that “Obama’s motto” was: “If I don’t go on taxpayer funded vacations & constantly fundraise then the terrorists win.” The joke, it turns out, is on Trump.
(8) No one expected us to win either of these byelections, but we can’t ignore how disappointing these results are,” he said, referring also to last week’s Richmond Park byelection.
(9) If Del Bosque really want to win this World Cup thingymebob, then he has got to tell Iker Casillas that the jig is up, correct?
(10) Perhaps there were some other generations in Portuguese football with more talent, but they didn’t win.
(11) The review will now be delayed for five years, leaving the next election to be fought on the existing constituency boundaries, and seriously damaging David Cameron's chances of winning an overall majority in 2015.
(12) Everyone is expecting them to win and I think that’s a double-edged sword.
(13) Unfortunately for the governor, he could win both states and still face the overwhelming likelihood of failure if he doesn't take Ohio, where the poll found Obama out front 51-43.
(14) Winning and losing were predicted to be more significant in determining cardiovascular responses for Type A's than for Type B's.
(15) The result will be yet another humiliating hammering for Labour in a seat it could never win, but hey, never mind.
(16) That’s why I thought: ‘I hope Tyson wins – even if he never gives me a shot.’ As long as the heavyweight titles are out of Germany we could have some interesting fights.
(17) In confidence rape, the assailant is known to some degree, however slight, and gains control over his victim by winning her trust.
(18) With their 43-8 win , the Seahawks did more than just produce one of the most dominant performances in Super Bowl history, they gave the city of Seattle its first major professional sports win in 35 years .
(19) Can somebody who is not a billionaire, who stands for working families, actually win an election into which billionaires are pouring millions of dollars?” Naming prominent and controversial rightwing donors, he said: “It is not just Hillary, it is the Koch brothers, it is Sheldon Adelson.” Stephanopoulos seized the moment, asking: “Are you lumping her in with them?” Choosing to refer to the 2010 supreme court decision that removed limits on corporate political donations, rather than address the question directly, Sanders replied: “What I am saying is that I get very frightened about the future of American democracy when this becomes a battle between billionaires.
(20) The only lesson I’ll learn from this is don’t win in the third round.