(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Witch
Definition:
(n.) A cone of paper which is placed in a vessel of lard or other fat, and used as a taper.
(n.) One who practices the black art, or magic; one regarded as possessing supernatural or magical power by compact with an evil spirit, esp. with the Devil; a sorcerer or sorceress; -- now applied chiefly or only to women, but formerly used of men as well.
(n.) An ugly old woman; a hag.
(n.) One who exercises more than common power of attraction; a charming or bewitching person; also, one given to mischief; -- said especially of a woman or child.
(n.) A certain curve of the third order, described by Maria Agnesi under the name versiera.
(n.) The stormy petrel.
(v. t.) To bewitch; to fascinate; to enchant.
Example Sentences:
(1) I fear that I will have to go through another witch-hunt in order to apply for this benefit."
(2) "I have been an evil witch, but now I can set light to the house and die happy."
(3) The experience of having had intercourse with the devil has in the past been regarded as evidence that the individual is a witch.
(4) Smith, a climate change sceptic who has also subpoenaed government scientists’ communications, has accused the attorney generals of a political witch-hunt and for causing a “chilling impact on scientific research and development”.
(5) In 2005, four years after Adam's body was found, two women and a man were convicted of child cruelty for torturing and threatening to kill an orphaned refugee who they claimed was a witch.
(6) The Witch Is Dead, the Wizard of Oz song which became the focus of an anti-Thatcher campaign on Facebook, was not just about where it would chart – but how much of it the BBC would play.
(7) A couple have been jailed for life for torturing and drowning a teenage boy they accused of being a witch.
(8) Leave voters, including a soldier, a mother expecting a “Brexit baby” due nine months after the vote, a rare chicken breeder, a witch, and a hammer-wielding Nigel Farage fan, have all been chosen to represent the various faces of Brexit on a new vase by the artist Grayson Perry .
(9) On Christmas Day 2010, Kristy's killer spoke to the boy's father, Pierre, accusing the 15-year-old of being a witch and threatening to kill him.
(10) Social unrest has become more and more likely, leading to an increasingly bold witch-hunt by the government against opposition voices .
(11) Lee denied the charges, saying he had never heard of the Revolutionary Organisation and denouncing the trial as a politically motivated witch-hunt by intelligence officials.
(12) The government has launched a separate royal commission into alleged union corruption, which unions have argued is a politically motivated “witch hunt”.
(13) Sure, the season’s story, which focuses on Vanessa Ives’s struggle to decode the “memoirs of the devil” and fight a hissing viper pit of Lucifer’s witches, may be pure pulp burlesque, but that’s just the first layer of Penny Dreadful’s charm.
(14) I could be the most beautiful drag queen in the world and the most evil witch of a person.
(15) Human rights campaigners have called on South Korea’s military to end its “witch-hunt” against gay servicemen, after an investigation into dozens of men prompted debate among presidential candidates over the country’s poor record on LGBT rights.
(16) "If we don't push home the idea that calling a child a witch will have grave consequences, then we will continue to have these kind of cases," said Ariyo.
(17) At one point, Evans was accused of bullying staff 20 years ago – a claim he said was ridiculous and the result of a witch-hunt.
(18) Season two crafted complex characters racked with existential ambivalence – heroines marked for the abyss, fragile, flammable outcasts and desolate prodigies, all of whose private pain was as palpable as the crimson bloodbath head witch Evelyn Poole soaks in.
(19) After working in a second-rate singing act with her older sisters and changing her name from Frances Gumm to Judy Garland, she was taken to Hollywood at the age of 13 by her fiercely ambitious mother (whom she later called "the real Wicked Witch of the West").
(20) He tried to capture its character – which he described as a “diabolical contraption, a dusty hunk of electric and mechanical hardware that reminded me of the disturbing 1950’s Quatermass science fiction television series” – in a near-lifesize two metre by three metre Portrait of a Dead Witch, which he also intended as a joke about the contemporary craze for computer-generated art.