(n.) A concretion or coagulation; esp. a soft, slimy, coagulated mass, as of blood; a coagulum.
(v. i.) To concrete, coagulate, or thicken, as soft or fluid matter by evaporation; to become a cot or clod.
(v. t.) To form into a slimy mass.
Example Sentences:
(1) The agent present in the serum which causes dissolution of the fibrin clot was isolated and identified as pepsinogen.
(2) A cDNA library prepared from human placenta has been screened for sequences coding for factor XIIIa, the enzymatically active subunit of the factor XIII complex that stabilizes blood clots through crosslinking of fibrin molecules.
(3) Congenitally deficient plasmas were used as the substrate for the measurement of procoagulant activities in a one-stage clotting assay.
(4) The risk of total occlusion and clot formation in the renal artery after subintimal injection is high.
(5) After 30 min incubation, blood clotting was observed in all 8 experiments with heparin concentrations of 0 and 1 U per ml; in 3 of 8 with 2 U per ml; and in none with greater than or equal to 3 U per ml.
(6) Purpura fulminans is the cutaneous manifestation of acute activation of the clotting mechanism resulting in massive hemorrhage due to an intravascular consumption coagulopathy.
(7) Electron microscopy showed that the clots consist mainly of a suspension of individual fibers, in contrast to clots made from native fibrinogen, which are highly branched.
(8) In testing the hypothesis that Lp(a) can competitively inhibit plasma clot lysis mediated by plasmin, the present study shows that Lp(a) significantly enhanced plasma clot lysis mediated by streptokinase or t-PA.
(9) After adding 125I-labeled fibrinogen to plasma, clots were made by adding thrombin and calcium and were then resuspended in normal plasma containing various concentrations of JTPI-1.
(10) Hematoma clot weighing 10 grams was removed through emergency craniotomy, followed by external decompression.
(11) These data suggest that, in addition to platelet activation, abnormalities of blood clotting, and particularly reduction of antithrombin III, may play a role in the thrombotic tendency associated with homocystinuria.
(12) is related to the presence of adherent clots along cerebral arteries and when severe may lead to cerebral infarction.
(13) Certain of the schistosomes were covered with a dense mass of interconnected blood platelets resembling a temporary haemostatic plug but not a blood clot.
(14) Concanavalin A was employed to study the role of platelet membrane glycoproteins in platelet-fibrin interactions during clot formation.
(15) Venous thrombosis occurred in 7 patients (17.5%) in the Kabi 2165 group, including two high, potentially emboligenic, localizations (5%), and in 4 patients (10%) in the standard heparin group, including 2 potentially emboligenic clots (5%).
(16) The main objective of these experiments was to develop and characterize a new experimental model of venous thrombosis, and determine whether a combination of vascular wall damage (crushing with hemostat clamps) and prolonged stasis produced more reproducible clots than prolonged stasis per se.
(17) The assay shows strong correlation with the immunologic assay for factor XIII catalytic subunit a (r = 0.94), the factor XIII dansylcadaverine assay (r = 0.83), and the factor XIII clot solubility test.
(18) Unlike thrombin, the newly isolated kallikrein-like enzyme did not cause formation of a fibrin clot when fibrinogen was mixed with the enzyme.
(19) It has to be assumed that in calves with respiratory distress syndrome--in analogy to pulmonary immaturity--the blood clotting mechanism is not yet fully developed.
(20) Five other patients with water-insoluble paraproteins were tested; two were clot-inhibitory.
Coagulum
Definition:
(a.) The thick, curdy precipitate formed by the coagulation of albuminous matter; any mass of coagulated matter, as a clot of blood.
Example Sentences:
(1) In clinical situations on donor sites and grafted full-thickness burn wounds, the PEU film indeed prevented fluid accumulation and induced the formation of a "red" coagulum underneath.
(2) Size of the thrombus, extension of the fibrin net and platelet adhesion are also modified by Defibrotide in 7-day-old thrombi where granulation tissue has replaced the original coagulum.
(3) The mitogenic, chemotactic, and synthetic responses of rat periodontal ligament (PDL) fibroblastic cells to epidermal growth factor (EGF), transforming growth factor-beta (TGF-beta), recombinant human platelet-derived growth factor (rhPDGF)-AB, rhPDGF-BB, natural (n) PDGF-AB, and insulin-like growth factor-I (IGF-I) were examined in vitro using PDL cells obtained from the coagulum of healing tooth sockets.
(4) On other areas of the luminal surface without endothelium, a red coagulum incorporating blood cells and fibrin was observed.
(5) All patients showed clinical signs of infection (loss of red reflex, diminished visual acuity, and intraocular lens coagulum) and P. aeruginosa was isolated from vitreous aspirates and unused lenses of the same lot.
(6) In the marginal area, bone can be found lying open with torn remnants, which are lying free in the coagulum.
(7) It was shown to interact non-covalently with semen coagulum.
(8) An initial fall in impedance of more than 10 omega was 78% sensitive and 88% specific for predicting subsequent evidence of tissue heating (interruption of conduction or an abrupt rise in impedance due to coagulum formation).
(9) Coagulum antibiotic concentrations are more than ten times lower than serum concentrations.
(10) The A. describe its similarity to plasminogen, its capacity to delay coagulum or embolus destruction and highlight its structural and functional similarity to lipid metabolism.
(11) However, lesions produced with radiofrequency current are relatively small and use of high power is limited by the impedance rise that occurs with desiccation of tissue and coagulum formation.
(12) The increase of the ejaculate volume was essentially due to an increase of the volume of the coagulum which closely correlated with total amount of fructose (from seminal vesicles) (r = 0.913, P less than 0.001).
(13) It was concluded that accelerated epithelization underneath the highly water vapor permeable polyetherurethane film dressing is associated with the presence of a gelatinous coagulum containing fibrin(ogen) and fibronectin.
(14) A clinical investigation was undertaken to compare regeneration of osseous defects following either osseous coagulum-bone blend grafts or open debridement procedures.
(15) With the high-fat diet, lipid digestion would occur in two phases; firstly, part of the fat would be lipolyzed quickly by pregastric esterase before clot formation in the abomasum; secondly, the rest of the lipids, slowly released by progressive lysis of the coagulum would be digested under the action of gastric and pancreatic lipases.
(16) Since only water vapor permeates through the PEU dressing, the wound exudate underneath is condensed into a gelatinous coagulum.
(17) This coagulum layer contained an abundant amount of fibrin(ogen) and fibronectin.
(18) Although a coagulum is formed, this is quite different from the typical hard copulatory plug that occurs in common laboratory murids; it may possibly reduce sperm backflow from the lower region of the female reproductive tract.
(19) They investigated the time needed for haemostasis, for adequate adherence of the coagulum to the wound and adequate hardness of the coagulum.
(20) The risk of craniotomy-induced bleeding from the aneurysm was thought to be low, since it was unruptured and was packed with coagulum.