(superl.) Large in bulk, or composed of large parts or particles; of inferior quality or appearance; not fine in material or close in texture; gross; thick; rough; -- opposed to fine; as, coarse sand; coarse thread; coarse cloth; coarse bread.
(1) Epithelial thymoma is characterized by coarse-fiber stroma, perivascular grouping of cell elements and the lack of glycogen in them.
(2) Foveal involvement included coarse foveal granularity, thinning of the foveal retinal pigment epithelium, increasing encirclement of the fovea with focal areas of atrophy, and minimal macular drusen.
(3) In 11 of these 20 patients, visual sensitivity to detail of medium coarseness was markedly degraded, even though sensitivity to both coarse and fine detail was unimpaired.
(4) In it he translated Trump’s coarse ramblings into charming straight talk and came up with the phrase “truthful hyperbole”, which captures brilliantly an approach to business and politics in which everything is the greatest, the most beautiful.
(5) Characteristic coarse facial features and shortness of stature were observed in all cases.
(6) The pulp cavity is reduced in size with age (maturation stage), in which the characteristic three vascular layers are changed into a one-layer coarse terminal capillary network which converges directly with the main venules.
(7) (3) Their operative findings were different from ordinary Graves' goiters in that colors of the goiter were yellow-red or gray-red, surface was rough and coarse, consistency was firm, and adhesions with the adjacent connective tissue were noted.
(8) Attempts were made to purify the LH-releasing substance extracted from the leaves of Avena sativa by means of two-step chromatographic procedures using a weakly acidic ion-exchange resin (CG-50,type II) and DEAE-Sephadex A-25 (coarse) with successful results.
(9) First-time measurements of the potentially toxic inorganic species of arsenic (arsenite and arsenate) have been obtained in fine (less than 2.5 microns AD) and coarse (greater than 2.5 microns AD) atmospheric particles in the Los Angeles area.
(10) An abnormal great number of microtubules and coarsed fibers were frequently randomly scattered throughout the cytoplasmic droplet.
(11) Motorized linear slides used as micromanipulators for biological use suffer from 3 problems: vibration at low speed, poor ergonomic design of the controller and slow coarse positioning.
(12) Each antibody stained 2 populations of cortical nonpyramidal neurons: (1) A small number of large, intensely stained cells that give rise to long, coarsely beaded processes; (2) a relatively large number of small, lightly stained cells that are embedded in dense plexuses of stained punctate profiles.
(13) In the Pagalunggan subdistrict, all females used uniodised salt with 17.6% using fine salt, 20% using coarse salt and the remainder using both fine and coarse salt.
(14) Thygeson's keratitis is characterized by a coarse punctate epithelial keratitis with almost no hyperaemia of the conjunctiva.
(15) The particles selected by CYBEST as "abnormal cells" at the stage of coarse scanning were examined by direct microscopy to determine whether they were actural cells or not.
(16) Fine wrinkling, coarse wrinkling, sallowness, looseness, and hyperpigmentation were significantly improved with tretinoin therapy.
(17) Coarse, linear densities are also observed, and pleural effusion is seen in many patients.
(18) Serves 4 100g butter, at room temperature 150g flour 50g ground almonds 30g suet 1 egg yolk 50g cooked chestnuts, chopped 5 tbsp chopped fresh thyme Salt and black pepper For the leeks 1kg leeks, trimmed 100g butter Salt and pepper 200ml double cream 1 tsp nutmeg 1 To make the crumble topping, work the butter into the flour until it resembles coarse breadcrumbs, then add the ground almonds and suet.
(19) 400g cooked or tinned butterbeans 1 tsp ground cumin 10ml lemon juice ¼ clove garlic, peeled and finely minced 1 small handful picked flat-leaf parsley, finely chopped 1 tbsp plain flour (gluten-free flour also works fine) 1 tsp salt 1 egg 1 spring onion, trimmed and finely sliced 50g breadcrumbs 100g feta (or other crumbly goat's or sheep's cheese) Put the butterbeans, cumin, lemon juice, garlic, parsley, flour, salt and egg in a food processor and blitz to a coarse paste: you don't want the mix fully pureed, otherwise the burgers will be too wet and will fall apart on the grill.
(20) In women who received free-silicone injections, coarse calcifications developed in three, and gross nodularity with calcified silicone granulomas developed in one.
Gritty
Definition:
(a.) Containing sand or grit; consisting of grit; caused by grit; full of hard particles.
(a.) Spirited; resolute; unyielding.
Example Sentences:
(1) Given his background, Boyle says, growing up in a council house near Bury, with his two sisters (one a twin) and his strict and hard-working parents (his mum worked as a dinner lady at his school), he should by rights have been a gritty social realist, but that tradition never appealed to him.
(2) San Francisco Tenderloin map They could potentially gentrify this gritty, 50-block swath of downtown into condos, lofts, hipster bars, organic cafes and yoga studios, as has happened in other parts of San Francisco and the Bay area.
(3) Concluding that he didn't really want a career as a gritty Northern Irish realist, Harvey decided to train as a teacher.
(4) Sitting in the bar at the Lowry theatre in Salford’s Media City, Shindler is talking about the word “gritty”.
(5) Click here to view video This year has been all about exciting gritty modern TV dramas.
(6) A gritty town battered by the decline of its lumber industry, it is mocked as hicksville by its rival, snootier neighbour, the university city Eugene, which Groening renamed Shelbyville.
(7) It manages to be both hard-hitting and emotional, gritty and warm."
(8) The chief executive is pinning early hopes on Breaking Bad, a gritty US drama in which a chemistry teacher with terminal cancer sets up a crystal meth lab, which was barely noticed when it aired on 5USA, although for all its merits it might not exactly be classified as family entertainment.
(9) Yet there is a tendency to switch off from this conversation as it moves from ambitious words and statements on to the nitty gritty of implementation.
(10) Bellows is known for his powerful paintings representing the hardship and desperation and grittiness of life in New York as it emerged in to the 20th century.
(11) "There is plenty of gritty contemporary life on the wrong side of the tracks, but there is also a ridiculous story of revenge.
(12) The chondroblastoma was located in a small gritty mass at one pole of the cyst, which could have easily been overlooked.
(13) That’s a difficult exercise, particularly with all the lawyers involved in the process and looking at the nitty-gritty of every word that is written down,” Zarif told journalists during a visit to Madrid.
(14) Fifteen years ago, the flag was the subject of a gritty partisan struggle in the state house and an economic boycott by the NAACP.
(15) Symptoms of grittiness and morning stickiness were more frequent among patients without enhanced responses.
(16) Prey is a gritty, concretey number, and while Reinhardt may be the least-kempt of the cast, every character drinks too much, looks constantly knackered and is therefore entirely believable.
(17) Of 440 amputations for vascular disease, 193 were above-knee, 193 below-knee, 15 Gritti-Stokes, 15 through-knee and 24 bilateral.
(18) In her day this was a gritty neighbourhood and it hasn’t changed much, with a shabby market by the metro station and blocks of peeling townhouses; this is the real, old Paris, the world she sang about, with its desperate cast of thieves and tramps and lovers.
(19) "That kind of geographic splitting can certainly create opportunities for speciation, so it's a plausible mechanism, but I'd like to see a more extensive and fine-grained review of the evidence than Mark and his coauthors could cram into their paper – one that gets into the nitty-gritty of where the basins were, when the marine barriers between them would have appeared and disappeared, and what lived in them."
(20) Fishwick's layer upon layer of northern grittiness versus southern sniffiness will be grating for some.