(n.) The dried leaf of a South American shrub (Erythroxylon Coca). In med., called Erythroxylon.
Example Sentences:
(1) In the UK, Coca-Cola owns Innocent smoothies while PepsiCo has Tropicana.
(2) The low pH carbonated drink, coca-cola, and a blackcurrent cordial produced no effects.
(3) Potential, polarization, and pH measurements were performed before and after Coca-Cola and orange juice rinsing and intake of sweets, which were used as test products.
(4) In the nineteenth century, some natives of Peru noticed circumoral numbness, euphoria and analgesia after chewing the leaves of the Erythroxylen coca bush.
(5) The beverages tested were a cola beverage ("Coca-Cola"), a carbonated orange drink ("Jaffa") and single strength orange juice.
(6) Nestlé and the other water giants, Coca-Cola and Pepsi, have often cut deals with relatively isolated, impoverished rural communities whereby they take a percentage of the local water supply, paying enough to keep municipal rates low for local residents.
(7) Cocaine base or white coca paste was smoked heavily by 188 patients who came to four hospitals of Lima, Peru.
(8) Red Bull is now the UK's third bestselling soft drink, after Pepsi and Coca-Cola.
(9) Coca leaf, from which cocaine and extracts for some commercial carbonated soft drinks are obtained, remains relatively unknown by the medical and allied professions elsewhere.
(10) In our study of patients with anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) we found a highly significant association of COCA with ALCAPA (85%), although no patient with ALCAPA in this study had evidence of tracheal stenosis documented in the hospital chart.
(11) Good to see that Coca-Cola are paying homage to the Sheffield derby match with those stripes on the pitch."
(12) Meanwhile, the government has suspended its aerial coca crop spraying program and is setting out its new social investment packages.
(13) Daily chewing of coca leaves was reported by 70 (65%) respondents.
(14) At the very least, it would seem to be tinkering with the formula of the biggest spiritual brand in the world, analogous to Coca-Cola changing its famous recipe in 1985 .
(15) Its partners are the Coca-Cola Foundation and the Beverage Institute.
(16) The fumigations ruined our food crops but the coca would just grow back stronger.” As the herbicide rained down on their farms, NGO’s with Plan Colombia cash offered coca growers were offered incentives to substitute coca for legal crops.
(17) Lord Coe has staunchly defended the sponsorship of the London Olympics by fast food and soft drinks companies, arguing that the investment by brands such as Coca-Cola and McDonald's is essential to making the event a success.
(18) The group Georgia Prospers, of which Moore is a member, includes a range of businesses – from Fortune 500 companies like Delta, Coca-Cola, and Home Depot to smaller ones across the state – in support of “treating all Georgians and visitors fairly”.
(19) He began in the cocaine business smuggling small quantities of coca paste from Peru to Colombia.
(20) Instead, the least attractive aspects of London 2012, the ZiL lanes and the Visa-only policy and McDonald's and Coca-Cola as purveyors of sustenance to a sporting nation, were smothered not only by the competition but by the ocean of good humour fostered by the joviality of the volunteers, the inspirational architecture and the attention given to the natural landscape (with apologies to those who had to move to make room for it all).
Ecgonine
Definition:
(n.) A colorless, crystalline, nitrogenous base, obtained by the decomposition of cocaine.
Example Sentences:
(1) The plasma was analyzed for COC and its metabolites, benzoylecgonine (BE) and ecgonine methyl ester (EME).
(2) The cocaine metabolites (-)-norcocaine, (-)-benzoylecgonine and (-)-ecgonine methyl ester inhibited BChE with Ki values of 15, 76 and 1300 microM, respectively.
(3) Increased chromatographic retention and detection sensitivity has been obtained by formation of the t-butyldimethylsilyl derivative of ecgonine methyl ester which was found to be stable in the HPLC mobile phase for at least 1 week.
(4) The influence of ecgonine, tropine, tropinon, and some of their derivatives, propan, N-methylpyrrholidine, N-methylpiperidine on impulse summation in the central nervous system, conditioned reflex of avoidance, antagonism to hexenal, synergisim to cocaine and also their toxicity (LD50) have been studied under experimental conditions.
(5) Benzoylnorecgonine and ecgonine were excreted in higher amounts and benzoylecgonine and norecgonine in lower amounts in the acute than in the chronically treated dogs.
(6) Norcocaine, benzoylnorecgonine, benzoylecgonine, ecgonine, norecgonine, ecgonine methyl ester and unidentified compounds were urinary metabolites of cocaine in both groups.
(7) Rapid, reliable, sensitive, qualitative, and quantitative methods using small urine volumes (0.2-0.5 mL) were developed primarily for confirmation of marijuana, cocaine, benzoylecgonine, ecgonine methyl ester, morphine, codeine, amphetamine, methamphetamine, and phencyclidine.
(8) Ecgonine methyl ester was much less potent than cocaine, and O-benzoyl ecgonine was ineffective.
(9) A gas chromatographic procedure has been developed for the simultaneous determination of cocaine and benzoyl ecgonine in urine specimens.
(10) Twenty hair samples obtained from Bolivian mine workers who chewed 3-8 g of coca leaves daily for several years were analyzed for cocaine and its main metabolites, benzoylecgonine (BZE) and ecgonine methyl ester (EME).
(11) Ecgonine methyl ester appears to have no significant effect on food intake or body weight.
(12) Mixtures of the naturally occurring (-)-cocaine and synthetically produced (+)-cocaine were hydrolyzed in water to (+) and (-)-benzoyl ecgonine.
(13) Cocaine and its principal metabolite, benzoyl ecgonine, were isolated from the urine of four hospitalized children who had been exposed to the smoke of freebase cocaine ("crack") used by their adult caretakers.
(14) A sensitive high-performance liquid chromatographic method using 3-bromomethyl-6,7-dimethoxy-1-methyl-2(1H)-quinoxalinone (Br-DMEQ) as a fluorescent labeling reagent is described for the determination of benzoylecgonine (BE) and ecgonine (EC).
(15) A method for the simultaneous analysis of cocaine (COC), derivatized benzoylecgonine (BE), and derivatized ecgonine methyl ester (EME) has been developed.
(16) The excretion kinetics of cocaine (C) and its two major metabolites, benzoylecgonine (BZ) and ecgonine methyl ester (EME), were determined by collecting all urine for 30 h from 5 cocaine users (subjects C, D, E, F, and G) given bolus doses followed by exponential cocaine infusions that delivered doses of 253 (subject C), 444 (subjects D, E, and F), and 700 mg (subject G).
(17) Other metabolites present were benzoylecgonine, ecgonine methyl ester, ecgonine, ecgonidine methyl ester, norcocaine, p-hydroxycocaine, and m-hydroxycocaine.
(18) This provided the basis for the determination of cocaine, benzoylecgonine and ecgonine from the same sample.
(19) The effects of dietary supplements of cocaine, ecgonine methyl ester, a coca leaf extract and powdered coca leaves on body weight and overall body metabolism were studied in the rat.
(20) Cocaine, benzoylecgonine, benzoylnorecgonine, norcocaine, ecgonine methyl ester but not ecgonine formed distinct molecular complexes with calcium chloride of the general formula [B. CaC12-2H20].