What's the difference between combination and hybridization?

Combination


Definition:

  • (n.) The act or process of combining or uniting persons and things.
  • (n.) The result of combining or uniting; union of persons or things; esp. a union or alliance of persons or states to effect some purpose; -- usually in a bad sense.
  • (n.) The act or process of uniting by chemical affinity, by which substances unite with each other in definite proportions by weight to form distinct compounds.
  • (n.) The different arrangements of a number of objects, as letters, into groups.

Example Sentences:

  • (1) From 1982 to 1989, bronchoplasty or segmental bronchoplasty and pulmonary arterioplasty in combination with lobectomy and segmentectomy were performed for 9 patients with central type lung carcinoma.
  • (2) Combinations of maximum amounts of glucagon and the cyclic nucleotide did not produce a greater effect than either agent alone.
  • (3) Combination therapy was most effective in patients receiving HCTZ prior to enalapril.
  • (4) Lucy and Ed will combine coverage of hard and breaking news with a commitment to investigative journalism, which their track record so clearly demonstrates”.
  • (5) The combined immediate and delayed responses to fleas in the dog are as observed by other investigators in man and guinea pigs.
  • (6) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
  • (7) Recently, it has been shown that radiation therapy, alone or combined with chemotherapy, can be successful.
  • (8) More than 2 months after the combined treatment were required for the suppression.
  • (9) By combined histologic and cytologic examinations, the overall diagnostic rate was raised to 87.7%.
  • (10) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
  • (11) The combined analysis of pathogenesis and genetics associated with the salmonella virulence plasmids may identify new systems of bacterial virulence and the genetic basis for this virulence.
  • (12) Multiple overlapping thin 3D slab acquisition is presented as a magnitude contrast (time of flight) technique which combines advantages from multiple thin slice 2D and direct 3D volume acquisitions to obtain high-resolution cross-sectional images of vessel detail.
  • (13) Handing Greater Manchester’s £6bn health and social care budget over to the city’s combined authority is the most exciting experiment in local government and the health service in decades – but the risks are huge.
  • (14) Classical treatment combining artificial delivery or uterine manual evacuation-oxytocics led to the arrest of bleeding in 73 cases.
  • (15) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
  • (16) When the data correlating DHT with protein synthesis using both labelling techniques were combined, the curves were parallel and a strong correlation was noted between DHT and protein synthesis over a wide range of values (P less than 0.001).
  • (17) Infection with opportunistic organisms, either singly or in combination, is known to occur in immunocompromised patients.
  • (18) Side effect incidence in patients treated with the paracetamol-sobrerol combination (3.7%) was significantly lower than that observed in subjects treated with paracetamol (6.1% - P less than 0.01), salicylics (25.1% - P less than 0.001), pyrazolics (12.6% - P less than 0.001), propionics (20.3%, P less than 0.001) or other antipyretics (17.9% - P less than 0.001).
  • (19) Because of the small number of patients reported in the world literature and lack of controlled studies, the treatment of small cell carcinoma of the larynx remains controversial; this retrospective analysis suggests that combination chemotherapy plus radiation offers the best chance for cure.
  • (20) Because it has been suggested that the lathyrogen, BAPN, may stimulate the release of proteases, the protease inhibitors Trasylol and epsilon-aminocaproic acid (EACA) were given alone or in combination to BAPN-treated rats.

Hybridization


Definition:

  • (n.) The act of hybridizing, or the state of being hybridized.

Example Sentences:

  • (1) These data suggest that the hybrid is formed by the same mechanism in the absence and presence of the urea step.
  • (2) We propose that this dependence on coexpression reflects the association between the LTA::STa hybrids and LTB subunits.
  • (3) Five probes of high specificity to individual chromosomes (chromosomes 3, 11, 17, 18 and X) were hybridized in situ to metaphase chromosomes of different individuals.
  • (4) By hybridization studies, three plasmids in two forms (open circular and supercoiled) were detected in the strain A24.
  • (5) In the present study, the expression of type IV collagen associated with the basal membrane (BM) was studied histochemically (indirect immunoperoxidase-antiperoxidase) in cervical human papillomavirus (HPV) lesions (diagnosed using in situ DNA hybridization) of different grades.
  • (6) The expression of the mRNA for mouse testicular lactate dehydrogenase (LDH-X) was examined by RNA:cDNA hybridization in situ in the testis and by Northern analyses of meiotic and postmeiotic spermatogenic cell populations.
  • (7) Thermal stabilities (Tm's) of the hybrid between the 2'-O-methyl ribooligomer and the complementary ribooligomer and of the related hybrids are compared.
  • (8) Five of them had a fast-moving Eco RI fragment 5.6 kb long that hybridized with zeta-specific probe but not with alpha-specific probe.
  • (9) DNA from 9% (47 of 529) of the E. coli colonies tested hybridized with the ST probe, whereas only 5% (28 of 529) produced ST as measured by the suckling mouse bioassay.
  • (10) Northern hybridization analysis of R. toruloides RNA with a restriction fragment encoding part of the PAL gene indicates that PAL mRNA is 2.5 kilobases in length.
  • (11) Furthermore, these data support our previous suggestion that the expression of human lymphoid differentiation antigens in human-mouse lymphoid hybrids is influenced by the differentiation stage of the fusion partners.
  • (12) Using as little as 0.2 ml of human blood per culture plate, we successfully cloned hybridomas and established a hybrid cell line producing anti-peroxidase antibody.
  • (13) In situ hybridization of SMG sections showed that Aeg-1 and Aeg-2 transcripts are produced by the cells of granular convoluted tubules.
  • (14) Recently, it has been proposed that beta-adrenergic receptors of rat fat cells are neither beta 1 nor beta 2 in character but rather an 'isoreceptor,' 'hybrid,' or 'beta 3' [Br.
  • (15) A plaque hybridization assay was adapted to rotavirus.
  • (16) We isolated soft agar colonies (a-subclones) and sub-clones from foci (h-subclones) of both hybrids, and, as a control, subclones of cells from random areas without foci of one hybrid (BS181 p-subclones).
  • (17) Moreover, nick-translated [32-P]-pCS75, which is a pUC9 derivative containing a PstI insert with L and S subunit genes (for RuBisCO) from A. nidulans, hybridizes at very high stringency with restriction fragments from chromosomal DNA of untransformed and transformed cells as does the 32P-labeled PstI fragment itself.
  • (18) The Thy-1.2 antigen, expressed on the surface of the lymphoma parent but not the fibroblast parent, was not detected on the hybrids.
  • (19) These images were previously determined by using a recently developed hybrid optical-digital method.
  • (20) The probe encoding LHCPII hybridizes to RNAs of 9.5 and 6.6 kb on northern blots of total RNA while the 3'-end probe hybridizes only to the 6.6 kb RNA.