(1) In each sheep there was a significant negative correlation between the glucose and corticosteroid concentrations in both maternal and fetal plasma, and there were positive correlations between the maternal and fetal plasma concentrations of glucose, and between the glucose and fructose concentrations of fetal plasma.
(2) Synthesis of choline esterase on the medium with acetylcholine at a concentration of 1% was increased more than twofold upon addition of glucose at a concentration of 0.1%.
(3) Steady-state values of cell, glucose, and cellulase concentration oxygen tension, and outlet gas oxygen partial pressure were recorded.
(4) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(5) Arachidic acid was without effect, while linoleic acid and linolenic acid were (on a concentration basis) at least 5-times less active than arachidonic acid.
(6) The fraction of the viral dose which became cell associated was independent of the incubation temperature and increased with increasing target membrane concentration.
(7) Maximum increases in portal plasma secretin concentrations of 143, 146 and 190% and maximum increases in VIP of 116, 155 and 147% after, respectively, intraduodenal 0.1 M NaHCO3, 0.1 M Na2CO3, and 0.025 M NaOH were found.
(8) ), the concentration of AMPO in the hypothalamus was 5.4 times the concentration at 20 h after one injection.
(9) In cardiac tissue the adenylate system is not a good indicator of the energy state of the mitochondrion, even when the concentrations of AMP and free cytosolic ADP are calculated from the adenylate kinase and creatine kinase equilibria.
(10) We similarly evaluated the ability of other phospholipids to form stable foam at various concentrations and ethanol volume fractions and found: bovine brain sphingomyelin greater than dipalmitoyl 3-sn-phosphatidylcholine greater than egg sphingomyelin greater than egg lecithin greater than phosphatidylglycerol.
(11) Cyclic AMP stimulated phosphorylation by [gamma-32P]ATP of two proteins of apparent Mr = 20,000 and 7,000 that were concentrated in sarcoplasmic reticulum, but the stimulation was markedly dependent on the presence of added soluble cyclic AMP-dependent protein kinase.
(12) We conclude that the SHBG concentration strongly affects this estimation.
(13) Ursodeoxycholate was the only dihydroxy bile salt which was able to solubilize phospholipid (although not cholesterol) below the critical micellar concentration.
(14) The fluctuations in [Ca2+]i measured with fura-2 were synchronized among the population of cells observed and were sensitive to extracellular Ca2+ concentration ([Ca2+]o).
(15) The observed relationship between prorenin and renin substrate concentrations might be a consequence of their regulation by common factors.
(16) In the presence of insulin, a qualitatively similar pattern of increasing responses to albumin is observed; the enhancement of each response by insulin is, however, only slightly potentiated by higher albumin concentrations.
(17) We maximize an objective function that includes both total production rate and product concentration.
(18) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(19) Thus adrenaline, via pre- and post-junctional adrenoceptors, may contribute to enhanced vascular smooth muscle contraction, which most likely is sensitized by the elevated intracellular calcium concentration.
(20) The specific activities of extracts from cells grown under phototrophic and aerobic conditions were similar and not affected by the concentration of iron in the growth media.
Hard
Definition:
(superl.) Not easily penetrated, cut, or separated into parts; not yielding to pressure; firm; solid; compact; -- applied to material bodies, and opposed to soft; as, hard wood; hard flesh; a hard apple.
(superl.) Difficult, mentally or judicially; not easily apprehended, decided, or resolved; as a hard problem.
(superl.) Difficult to accomplish; full of obstacles; laborious; fatiguing; arduous; as, a hard task; a disease hard to cure.
(superl.) Difficult to resist or control; powerful.
(superl.) Difficult to bear or endure; not easy to put up with or consent to; hence, severe; rigorous; oppressive; distressing; unjust; grasping; as, a hard lot; hard times; hard fare; a hard winter; hard conditions or terms.
(superl.) Difficult to please or influence; stern; unyielding; obdurate; unsympathetic; unfeeling; cruel; as, a hard master; a hard heart; hard words; a hard character.
(superl.) Not easy or agreeable to the taste; stiff; rigid; ungraceful; repelling; as, a hard style.
(superl.) Rough; acid; sour, as liquors; as, hard cider.
(superl.) Abrupt or explosive in utterance; not aspirated, sibilated, or pronounced with a gradual change of the organs from one position to another; -- said of certain consonants, as c in came, and g in go, as distinguished from the same letters in center, general, etc.
(superl.) Wanting softness or smoothness of utterance; harsh; as, a hard tone.
(superl.) Rigid in the drawing or distribution of the figures; formal; lacking grace of composition.
(superl.) Having disagreeable and abrupt contrasts in the coloring or light and shade.
(adv.) With pressure; with urgency; hence, diligently; earnestly.
(adv.) With difficulty; as, the vehicle moves hard.
(adv.) Uneasily; vexatiously; slowly.
(adv.) So as to raise difficulties.
(adv.) With tension or strain of the powers; violently; with force; tempestuously; vehemently; vigorously; energetically; as, to press, to blow, to rain hard; hence, rapidly; as, to run hard.
(adv.) Close or near.
(v. t.) To harden; to make hard.
(n.) A ford or passage across a river or swamp.
Example Sentences:
(1) Lucy and Ed will combine coverage of hard and breaking news with a commitment to investigative journalism, which their track record so clearly demonstrates”.
(2) Sierra Leone is one of the three West Africa nations hit hard by an Ebola epidemic this year.
(3) Topical and systemic antibiotic therapy is common in dermatology, yet it is hard to find a rationale for a particular route in some diseases.
(4) Given Australia’s number one position as the worst carbon emitter per capita among major western nations it seems hardly surprising that islanders from Fiji, Samoa, Vanuatu and other small island developing states have been turning to Australia with growing exasperation demanding the country demonstrate an appropriate response and responsibility.
(5) They had learned through hard experience what Frederick Douglass once taught -- that freedom is not given, it must be won, through struggle and discipline, persistence and faith.
(6) In 60 rhesus monkeys with experimental renovascular malignant arterial hypertension (25 one-kidney and 35 two-kidney model animals), we studied the so-called 'hard exudates' or white retinal deposits in detail (by ophthalmoscopy, and stereoscopic color fundus photography and fluorescein fundus angiography, on long-term follow-up).
(7) It is a moment to be grateful for what remains of Labour's hard left: an amendment to scrap the cap was at least tabled by John McDonnell and Jeremy Corbyn but stood no chance.
(8) She stopped working only when the pain made it hard for her to get to work.
(9) He was reclusive, I know that, and he was often given a hard time for it.
(10) This defeat, though, is hardly a good calling card for the main job.
(11) Since this test is easily performed and hardly stresses the patient, it should routinely be the initial one for the diagnosis of renal osteopathy.
(12) Never become so enamored of your own smarts that you stop signing up for life’s hard classes.
(13) But I don't wish to be too hard on the judge for not taking that view.
(14) Our campaign has been going for some time and each step in our progress has been hard won, by campaigners paid and volunteer alike.
(15) I am rooting hard for you.” Ronald Reagan simply told his former vice-president Bush: “Don’t let the turkeys get you down.” By 10.30am Michelle Obama and Melania Trump will join the outgoing and incoming presidents in a presidential limousine to drive to the Capitol.
(16) All the same, it's hard to approach the school, which charges nearly £28,000 for boarders and nearly £19,000 for day girls and is sometimes called "the girls' Eton", without a few prejudices.
(17) Governmental officials as well as medical scientists in Taiwan have worked hard in recent years to develop and to implement various measures, such as prenatal diagnosis and neonatal screening, to lower the incidence of hereditary diseases and mental retardation in the population.
(18) Cooper, who was briefly a social worker in Los Angeles, also suggests working hard to build a rapport with colleagues in hotdesking situations.
(19) Critics of wind power peddle the same old myths about investment in new energy sources adding to families' fuel bills , preferring to pick a fight with people concerned about the environment, than stand up to vested interests in the energy industry, for the hard-pressed families and pensioners being ripped off by the energy giants.
(20) The spirit is great here, the players work very hard, we kept the belief when we were in third place and now we are here.