(n.) The act of constraining, or the state of being constrained; that which compels to, or restrains from, action; compulsion; restraint; necessity.
Example Sentences:
(1) Poor lipophilicity and extremely low plasma concentrations impose severe constraints.
(2) Specifically, we apply techniques of data preprocessing, orthogonality constraints, and validation of solutions in a complete TC analysis, for the first time using actual MEP data.
(3) When this constraint was released by various treatments altering membrane structure UDP-glucose markedly inhibited bilirubin glucuronidation.
(4) For each theory, a constraint on preformance is proposed based on interference between the "analytic" and "synthetic" pitch perception modes.
(5) spectroscopy for the collection of conformational constraints, calculation of the protein structure from the n.m.r.
(6) Subjects initially chose to work for the higher rated food, but as the constraints for this food increased, subjects chose to work for the lower rated food.
(7) Dictated by underlying physicochemical constraints, deceived at times by the lulling tones of the siren entropy, and constantly vulnerable to the vagaries of other more pervasive forms of biological networking and information transfer encoded in the genes of virus and invading microorganisms, protein biorecognition in higher life forms, and particularly in mammals, represents the finely tuned molecular avenues for the genome to transfer its information to the next generation.
(8) Continuing pressure on household finances during the next 12 months will no doubt remain a constraint."
(9) Lateralization may be an expression of reflex constraints bound initially to the infant's tonic-neck posture, with later development less reflex-patterned during the acquisition of more sophisticated information-processing strategies.
(10) His anti-politics act may just be a shtick – pretending he's still on Have I Got News for You, satirising politics even though he's right at the centre of it – but it liberates him from the usual constraints.
(11) Given that lattice constraints strongly inhibit large-scale conformational changes these results allow us to identify the average solution structure with the 'open' conformer determined crystallographically.
(12) A dynamic optimization technique to minimize jerk cost under the constraint on jerk input was applied to interpret the results, assuming that a major goal of skilled movements was to produce optimally smooth movements.
(13) Its main advantages, when compared to previously available programs using the variable target function algorithm, are a significant reduction of the computation time, and a novel treatment of experimental distance constraints involving diastereotopic groups of hydrogen atoms that were not individually assigned.
(14) For one, the ability to raise a larger deposit is acting as a constraint.
(15) When the constraints are high, a Michaelis-Menten equation can be used to model the kinetics for interfacial concentrations lower than the concentration leading to the maximum reaction rate.
(16) Estimators of the model parameters are defined under general exact and stochastic linear constraints.
(17) A careful reorganization of priorities would thus be helpful in improving neonatal care in Jamaica, even in the presence of financial constraints.
(18) Emergence and spread of antibiotic-resistant bacteria is augmented in settings in which treatment may be inadequate because of socioeconomic constraints and where there is crowding and poor sanitation.
(19) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(20) Bias is controlled by the use of least-squares curve fitting for all assays, and constraints on the elimination of outlier points.
Limitation
Definition:
(v. t.) The act of limiting; the state or condition of being limited; as, the limitation of his authority was approved by the council.
(v. t.) That which limits; a restriction; a qualification; a restraining condition, defining circumstance, or qualifying conception; as, limitations of thought.
(v. t.) A certain precinct within which friars were allowed to beg, or exercise their functions; also, the time during which they were permitted to exercise their functions in such a district.
(v. t.) A limited time within or during which something is to be done.
(v. t.) A certain period limited by statute after which the claimant shall not enforce his claims by suit.
(v. t.) A settling of an estate or property by specific rules.
(v. t.) A restriction of power; as, a constitutional limitation.
Example Sentences:
(1) Serum levels of both dihydralazine and metabolites were very low and particularly below the detection limit.
(2) This should not be a serious limitation to the application of the RIA in the detection of venous thrombosis.
(3) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(4) Increased infusion flow rate did not increase the limiting frequency.
(5) The extent of the infectious process was limited, however, because the life span of the cultures was not significantly shortened, the yields of infectious virus per immunofluorescent cell were at all times low, and most infected cells contained only a few well-delineated small masses of antigen, suggestive of an abortive infection.
(6) Limited biopsic retroperitoneal lymphnode dissection subsequently extended following the result of the frozen section histology.
(7) In addition, the fact that microheterogeneity may occur without limit in the mannans of the strains suggests that antibodies with unlimited diverse specificities are produced directed against these antigenic varieties as well.
(8) The specific limited trypsinolysis of bacteriophage T7 RNA polymerase (T7RP) was performed in the presence of various components of the polymerase reaction and some GTP-analogs--irreversible inhibitors of the enzyme.
(9) This postulate is supported by a limited study of the serovars present among the isolates.
(10) Breast reconstruction should not be limited to the requiring patients, but should represent, in selected cases with favourable prognosis, an integrative and complementary procedure of the treatment.
(11) As increases to the Isa allowance are based on the CPI inflation figure for the year to the previous September, the new data suggests the current Isa limit of £15,240 will remain unchanged next year.
(12) Conditions for limited digestion of the heterodimer by subtilisin, removing only the carboxyl terminus, were determined.
(13) Furthermore the limit between hearing aid fitting an cochlear implantation is discussed.
(14) Comprehensive regulations are being developed to limit human exposure to contamination in drinking water by the United States Environmental Protection Agency (EPA) under the authority of the Safe Drinking Water Act (SDWA).
(15) Direct limiting effects of hypothermia on tissue O2 delivery and muscle oxidative metabolism as well as vasoconstriction and arteriovenous shunting associated with CPB procedures are likely to be involved in the above mentioned alterations of cell metabolism.
(16) Their disadvantages - the expensive equipment and the time-consuming procedure respectively - limit their widespread use.
(17) The lower limit (LL) of CBF autoregulation was calculated by a computerized program and tested for different factors for correction of the PaCO2-induced changes in CBF.
(18) Immunochemical techniques, in particular ELISA are available for only a very limited number of NM (e.g.
(19) Only one E. coli strain, containing two plasmids that encode endo-pectate lyases, exo-pectate lyase, and endo-polygalacturonase, caused limited maceration.
(20) Initiation of the alternative pathway by the cryptococcal capsule is characterized by a lag in C3 accumulation and the appearance of a limited number of focal initiation sites which resemble those observed when the alternative pathway is activated by zymosan and nonencapsulated cryptococci.