(n.) The heart or inner part of a thing, as of a column, wall, rope, of a boil, etc.; especially, the central part of fruit, containing the kernels or seeds; as, the core of an apple or quince.
(n.) The center or inner part, as of an open space; as, the core of a square.
(n.) The most important part of a thing; the essence; as, the core of a subject.
(n.) The prtion of a mold which shapes the interior of a cylinder, tube, or other hollow casting, or which makes a hole in or through a casting; a part of the mold, made separate from and inserted in it, for shaping some part of the casting, the form of which is not determined by that of the pattern.
(n.) A disorder of sheep occasioned by worms in the liver.
(n.) The bony process which forms the central axis of the horns in many animals.
(v. t.) To take out the core or inward parts of; as, to core an apple.
(v. t.) To form by means of a core, as a hole in a casting.
Example Sentences:
(1) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(2) Hoursoglou thinks a shortage of skilled people with a good grounding in core subjects such as maths and science is a potential problem for all manufacturers.
(3) Schneiderlin, valued at an improbable £27m, and the currently injured Jay Rodriguez are wanted by their former manager Mauricio Pochettino at Spurs, but the chairman Ralph Krueger has apparently called a halt to any more outgoings, saying: “They are part of the core that we have decided to keep at Southampton.” He added: “Jay Rodriguez and Morgan Schneiderlin are not for sale and they will be a part of our club as we enter the new season.” The new manager Ronald Koeman has begun rebuilding by bringing in Dusan Tadic and Graziano Pellè from the Dutch league and Krueger said: “We will have players coming in, we will make transfers to strengthen the squad.
(4) Core biopsy with computed tomography (CT) or ultrasound (US) guidance may be such an alternative, particularly when a spring-loaded firing device is used.
(5) Core enzyme, lacking omega subunit, catalyzed this reaction at a rate less than 1% that of holoenzyme.
(6) The specified region of the inner E2 core domain was highly homologous to the region of the E2 subunit of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.
(7) Each species has approximately 500 core histones cluster repeats per haploid genome.
(8) Thus there may be four types of LPS in PACI: one contains unsubstituted core polysaccharide and yields L2 on acid hydrolysis, another has short antigenic side-chains of the SR type and yields the LI fraction, while the two high molecular weight fractions are derived from core polysaccharides with different side-chains.
(9) Peptidoglycan synthesis is unaffected by the mutations affecting the core glycosyltransferases.
(10) The common atoms of the [3Fe-4S] and [4Fe-4S] cores agree within 0.1 A; the three common cysteinyl S gamma ligand atoms agree within 0.25 A.
(11) Tachycardia, pulmonary hypertension, increased venous oxygen desaturation, and increasing core temperature develop as the syndrome progresses.
(12) Some aspects of the life structure, of course, are also unconscious, namely, those having to do with attempted solutions to core personality conflicts and those reflecting modes of ego functioning.
(13) The interaction was specific for the DNA-binding activity of receptor, since H1 histones inhibit neither T3-binding activity nor core histone-binding activity of receptor.
(14) In contrast to the defect in another packaging-deficient mutant ts1201, the block in the formation of dense-cored, DNA-containing capsids in ts1233-infected cells at the NPT could not be reversed by transferring the cells to the permissive temperature in the presence of a protein synthesis inhibitor.
(15) Steady state levels of chloroplast mRNA encoding the core PSII polypeptides remain nearly constant in the light or the dark and are not affected by the developmental stage of the plastid.
(16) Viral particles in the cultures and the brain were of various sizes and shapes; particles ranged from 70 to over 160 nm in diameter, with a variable position of dense nucleoids and less dense core shells.
(17) The ternary complex consisting of a 65-kDa peptide originating from the proteoglycan core protein and a 43-kDa link protein bound to hyaluronic acid was purified from a clostripain digest of the rat chondrosarcoma aggregating proteoglycan and 14C-carbamylated with potassium [14C]cyanate.
(18) The binding of 125I-labeled core protein to immobilized fibronectin was inhibited by soluble fibronectin and by soluble cold core protein but not by albumin or gelatin.
(19) Intact wild-type cells, or those of a mutant in which the core region of the lipopolysaccharide was absent, were equally resistant to pronase treatment.
(20) The others had the structures galactosyl-galactosyl-xylosyl-4-methylumbelliferone and galactosyl-xylosyl-4-methylumbelliferone, respectively, representing the linkage region between the glycosaminoglycan chains and core protein, except that 4-methylumbelliferone replaced the amino acid.
Cure
Definition:
(n.) Care, heed, or attention.
(n.) Spiritual charge; care of soul; the office of a parish priest or of a curate; hence, that which is committed to the charge of a parish priest or of a curate; a curacy; as, to resign a cure; to obtain a cure.
(n.) Medical or hygienic care; remedial treatment of disease; a method of medical treatment; as, to use the water cure.
(n.) Act of healing or state of being healed; restoration to health from disease, or to soundness after injury.
(n.) Means of the removal of disease or evil; that which heals; a remedy; a restorative.
(v. t.) To heal; to restore to health, soundness, or sanity; to make well; -- said of a patient.
(v. t.) To subdue or remove by remedial means; to remedy; to remove; to heal; -- said of a malady.
(v. t.) To set free from (something injurious or blameworthy), as from a bad habit.
(v. t.) To prepare for preservation or permanent keeping; to preserve, as by drying, salting, etc.; as, to cure beef or fish; to cure hay.
(v. i.) To pay heed; to care; to give attention.
(v. i.) To restore health; to effect a cure.
(v. i.) To become healed.
(n.) A curate; a pardon.
Example Sentences:
(1) In all cases the polyarthritis is cured by anti-inflammatory treatment in 1-6 months.
(2) Because of the small number of patients reported in the world literature and lack of controlled studies, the treatment of small cell carcinoma of the larynx remains controversial; this retrospective analysis suggests that combination chemotherapy plus radiation offers the best chance for cure.
(3) The results indicated that roughly 25% of patients treated in this way will become hypothyroid after 5 years and that 85% are cured (need no further therapy during the follow-up period) using a single dose of iodine-131.
(4) We report a retrospective study of 107 cases of carcinoma of the sigmoid colon and upper rectum treated for primary cure at the University of California at Los Angeles Hospital between 1955 and 1970.
(5) HDAra-C in combination with anthracyclines is now considered to be a treatment which may afford some hope of a cure in a certain percentage of cases of adult acute non-lymphocytic leukemia.
(6) Since the plasmid-cured strains did not contain DNA sequences homologous to plasmid DNA, the gene for the free-inclusion protein must be encoded in the chromosome.
(7) In Stage I, seven relapses (relapse rate 6%) occurred after irradiation; three of them were cured with second-line therapies.
(8) Although patients treated with postoperative radiation therapy showed significantly extended survival rates as compared to those receiving surgical resection alone, the glioblastoma recurred within a 2cm margin of the primary site in more than 90% of the patients and conventional external radiation therapy with a doses of 50-60 Gy did not result in local cure.
(9) Percutaneous tenotomy performed only in patients recurring after temporary cure, drops the rate of recurrences to 13%.
(10) Long-term health conditions cannot be 'cured' – interventions are themselves long-term – taking place throughout the life of a patient.
(11) These alterations were not dependent on the prophage integration prior to curing, and no phage DNA was detected in cured cells by blot hybridisation.
(12) About 10% of the patients treated had “complete remission”, with no detectable cancer remaining - considered a cure if the patient is still cancer-free five years after diagnosis.
(13) Fifteen apparently normal patients who had been cured of cryptococcosis were found, as a group, to have impaired responsiveness to skin testing with cryptococcin and mumps, minimal leukocyte migration inhibition when stimulated with cryptococcin or C. neoformans, but normal group responses to cryptococcin in Cryptococcus-induced lymphocyte transformation.
(14) Ultimately, prevention is a better approach than cure.
(15) Nine among 21 patients (42%) who were initially treated by percutaneous puncture were definitively cured: all pseudocysts were smaller than 55 mm.
(16) The median duration of treatment for the clinical cures in osteomyelitis and septic arthritis were 29.5 days and 46 days respectively.
(17) Age at diagnosis (greater than or equal to 60 years vs less than or equal to 60 years), total number of involved sites, tumor bulk (mass size greater than or equal to 10 cm vs less than 10 cm), serum LDH (greater than or equal to 500 Units) and prompt achievement of complete remission following intensive combination regimens appear to be the most important variables predicting for cure in aggressive lymphomas.
(18) Clinical improvement did not occur in treated patients, and microbiologic cure was never obtained.
(19) The present findings imply that patients in whom an apparent cure has been brought about by conservative treatment may harbor latent malignancy.
(20) Oral potassium iodide therapy resulted in complete cure.