(n.) That which confines or contracts; a restraint; a shackle; a hindrance.
(n.) A device, usually of iron bent at the ends, used to hold together blocks of stone, timbers, etc.; a cramp iron.
(n.) A rectangular frame, with a tightening screw, used for compressing the joints of framework, etc.
(n.) A piece of wood having a curve corresponding to that of the upper part of the instep, on which the upper leather of a boot is stretched to give it the requisite shape.
(n.) A spasmodic and painful involuntary contraction of a muscle or muscles, as of the leg.
(v. t.) To compress; to restrain from free action; to confine and contract; to hinder.
(v. t.) To fasten or hold with, or as with, a cramp.
(v. t.) to bind together; to unite.
(v. t.) To form on a cramp; as, to cramp boot legs.
(v. t.) To afflict with cramp.
(n.) Knotty; difficult.
Example Sentences:
(1) He said: “Almost daily we hear from parents desperate to escape the single cramped room of a B&B or hostel that they find themselves struggling to raise their children in.
(2) Toxicity included an increase in body weight, cushingoid effects, muscle cramps, and tremors in both groups.
(3) Primary amenorrhea and cyclic, cramping lower abdominal pain was the common symptoms of all the patients.
(4) The 1st gynecologic consultant was called after the patient experienced severe cramps and passage of part of a placenta.
(5) Among the observed side effects were moderate pelvic cramps (20.9%), nausea (27%), fainting (4.8%); 61.3% of the women complained of fatigue.
(6) When there's a very limited stock of social housing, and very long waiting lists for people who need it, and lots of big families living in very cramped conditions, that isn't wrong at all.
(7) They also complained of exercise-induced stiffening and cramps of their leg muscles.
(8) Mark Leech, editor of ConVerse , the national newspaper for prisoners, said the former MP should expect "to find himself in a prison reception that is cramped, cold and busy – with up to 200 prisoners being processed each day".
(9) Despite a cramping, high-concept production set in a psychiatric ward, Richardson gave us a Richard resembling a monstrous child whose ravening will had yet to be curbed by social custom.
(10) He took Jessica's mobile out of her pocket; he carried their bodies down the stairs and, after checking no one was around, bundled them into the cramped boot of his car, bending their legs to fit them in; he collected petrol and bin bags (to protect his feet and thus conceal evidence); he drove to Lakenheath and found a lonely track; he got out where the vegetation grew thickly and he rolled the two girls down into the ditch; he climbed into the ditch and cut off their clothing - their red football shirts and their tracksuit trousers, their knickers, Holly's black bra which she and her mother had bought the day before - and then he poured petrol over their bodies and threw on a match.
(11) For chronic phantom and stump pain, burning sensations are treated with interventions designed to increase blood flow to the residual limb, whereas cramping sensations are treated with interventions that reduce muscle spasms.
(12) Post-prandial cramping abdominal pain may be an early symptom of thrombosis, demanding immediate anticoagulation.
(13) Our purpose was to evaluate the analgesic efficacy of single oral doses of ketoprofen 25, 50, and 100 mg compared with aspirin 650 mg and placebo in the relief of moderate to severe postepisiotomy, uterine cramping, or cesarean section pain.
(14) Photograph: Rozena Crossman Despite its small size, the café has a lighter and more modern atmosphere than the cramped bookshop next door, a famous hub for influential writers.
(15) The four-bedroom apartments are cramped and austere, but they sell for more than $100,000.
(16) Epidural morphine is used for postcesarean analgesia, and nonsteroidal antiinflammatory drugs are frequently administered to relieve uterine cramps after vaginal delivery.
(17) Subjective symptoms of venous hypertension were assessed by an analogue scale line considering four symptoms: swelling sensation, restless lower extremity, pain and cramps, and tiredness.
(18) Tommy Banks, Bolton's left back, was exhausted by his efforts to halt Matthews, contracting cramp in his shins, and four times leaving the field for treatment in the final quarter hour.
(19) 65% (140) quit because of side effects, usually pregnancy-like symptoms (such as nausea or weight gain), or menstrual symptoms (such as hemorrhaging or cramps).
(20) Funes Mori will commence a three-match ban on Saturday, John Stones was forced out of the derby with stomach cramps, Phil Jagielka is recovering from a hamstring strain and Seamus Coleman is almost certainly out with a similar injury.
Crick
Definition:
(n.) The creaking of a door, or a noise resembling it.
(n.) A painful, spasmodic affection of the muscles of some part of the body, as of the neck or back, rendering it difficult to move the part.
(n.) A small jackscrew.
Example Sentences:
(1) This suggests that (AGG)12 can form intra- and inter-molecular complexes by non-Watson-Crick, guanine:guanine base-pairing.
(2) It is demonstrated that this peculiar DNA fragment, under suitable conditions of concentration, salt and temperature, exclusively prefers to adopt a monomeric hairpin form with a stem of three Watson-Crick type base pairs and a loop of two residues.
(3) Hope u feel better xx” Bird told Channel 4’s political editor Michael Crick: “Natasha Bolter and I were in a consensual relationship between 18 September and 2 November, well after her admission to the list of approved candidates.
(4) The new Francis Crick Institute in London, now filling with 1,400 scientists, could be built and run for 10 years on that.
(5) The Watson-Crick H-bonded imino proton resonances were studied.
(6) The Watson-Crick alignment of the alkylG.T and alkylT.G mispairs may facilitate formation of these phosphodiester links, and this alignment rather than the strength of the base pairs and the extent of hydrogen bonding between them may be the crucial factor in the miscoding.
(7) The complex has one drug molecule intercalated between Watson--Crick base pairs of the nucleotide duplex.
(8) Recognition of the UACUAAC box thus relies, at least in part, on Watson-Crick base pairing with the yeast U2 analogue.
(9) A characteristic of Watson-Crick paired A X T and G X C bases is the pseudo 2-fold symmetry axis in the plane of the base pairs.
(10) The imino proton of T3 in the O6meG.T 12-mer and G3 in the O6meG.N 12-mer helix, which are associated with the modification site, resonate at unusually high field (8.5 to 9.0 ppm) compared to imino protons in Watson-Crick base pairs (12.5 to 14.5 ppm).
(11) We’d get recognised when we went out, and I developed a bad crick in my spine because I was staring at the pavement so much.
(12) The base pairing between piA and poly(U) in this system is probably of the Hoogsteen type (involving the 6-amino group and N7 of 3-isoadenosine) rather than of the Watson-Crick type.
(13) One of these models is a four-strand structure in which two duplexes of the Watson-Crick kind are specifically related by a twofold rotation axis and which has already been discussed in some detail.
(14) Nurse, too, believes the Crick is built on solid foundations.
(15) Molecular modeling shows that a stereochemically satisfactory structure can be build using C2'-endo sugars and a displacement of the Watson-Crick base-pair center from the helix axis of 2.5 A. Helical constraints of rise per residue (h = 3.26 A) and residues per turn (n = 12) were taken from fiber diffraction experiments of Arnott and Selsing (1974).
(16) The temperature variation of the imino proton NMR signals suggests that the hydrogen bonding in self-recognition is comparable in strength with that in a beta-DNA duplex, and NOE data are in accord with Watson-Crick rather than Hoogsteen base pairing.
(17) We describe NMR studies at superconducting fields which characterize aspects of the structure and stability of the 1 : 2 actinomycin-d-pG-C complex in solution as monitored at the Watson-Crick base pairs and backbone phosphate groups.
(18) From fibre diffraction data, models for triplex structures with poly(U).poly(A).poly(U) and poly(dT).poly(dA).poly(dT) have been proposed, in which the purine and one pyrimidine strand are Watson-Crick paired in an A' helix, and the other pyrimidine strand is Hoogsteen base-paired parallel to the purine strand along the major groove.
(19) The peptide forms a parallel, two-stranded coiled coil of alpha helices packed as in the "knobs-into-holes" model proposed by Crick in 1953.
(20) 7.09pm: On his blog, Newsnight's Michael Crick quotes an unnamed Liberal Democrat MP who told him he was amazed how much the Tories were willing to compromise.