(n.) Anything created; anything not self-existent; especially, any being created with life; an animal; a man.
(n.) A human being, in pity, contempt, or endearment; as, a poor creature; a pretty creature.
(n.) A person who owes his rise and fortune to another; a servile dependent; an instrument; a tool.
(n.) A general term among farmers for horses, oxen, etc.
Example Sentences:
(1) Maybe it’s because they are skulking, sedentary creatures, tied to their post; the theatre critic isn’t going anywhere other than the stalls, and then back home to write.
(2) "They are soul-less creatures pandering to the NRA ."
(3) The outcome is a belief that the Earth is being slowly strangled by a gaudy coat of impermeable plastic waste that collects in great floating islands in the world's oceans; clogs up canals and rivers; and is swallowed by animals, birds and sea creatures.
(4) While his more eminent predecessors, Gerald Durrell and John Aspinall, established that displaying wild creatures may occasionally be compatible with respect for them, zoos around the world have also sanitised – with extravagant claims about conservation, breeding programmes and species reintroduction – the essentially unchanged business of showing caged animals for cash.
(5) But nevertheless Theco is a fascinating creature because of both its place in the history of palaeontology and what it reveals about the south-west of England in prehistoric times.
(6) Although most studies emphasise the similarity of the australopithecines to modern man, and suggest, therefore, that these creatures were bipedal tool-makers at least one form of which (Australopithecus africanus--"Homo habilis", "Homo africanus") was almost directly ancestral to man, a series of multivariate statistical studies of various postcranial fragments suggests other conclusions.
(7) Highlights included TV series All Creatures Great and Small, competing in Strictly Come Dancing and starring in the touring stage production of Calendar Girls.
(8) They are two separate creatures with very different structures, more like a virus and a host: co-dependent but each with delusions about who is the superior form of life.
(9) Like traditional English philanthropists, the ladies running Hailsham believe that some wider public will feel more humanely towards these "poor creatures" if they can be shown to make art.
(10) Arthur Koestler in The Act of Creation expresses it thus: "From the Pythagoreans onward, through the Renaissance to our times, the oceanic feeling, the sense of participation in the mystery of the infinite, was the principal inspiration of the wingèd and flat-footed creature, the scientist."
(11) A campaign involving children in Syrian villages has latched on to the Pokémon Go craze, asking gamers in the west to take a break from their frenzied hunt for digital creatures to turn their attention to young people trapped in war zones.
(12) They could hardly believe it, this tiny creature sitting on the bench.
(13) The film uses new technology to transport viewers back 200 million years, to the time when pterosaurs lived – flying creatures with a wingspan of up to 14 metres.
(14) The unfairly maligned camel is a model of sleek, practical and elegant design compared with the clumsy creature the coalition has produced.
(15) When Rolls-Royce launched a $1.2m Year of the Dragon edition of its Phantom, with the creature hand-painted on its wheelbase and hand-stitched on to cushions, all eight sold in two months.
(16) Many of the patients anthropomorphise the seal, enjoy pretending that it is a real, living creature, with all the associated foibles.
(17) Executives at Lafarge global headquarters in Paris should take note that the second part of the name allocated by the molusc specialists who named this new creature is lafargei.
(18) In some ways, roaches are no different to gorillas, gerbils or iguanas, or any other creatures that we don’t routinely eat.
(19) Records show there were many reports of beaching whales in the Netherlands in the early 17th century, prompting a surge of public interest in the creatures.
(20) Sir David suggested spyholes to allow the public to watch the gorillas without the creatures realising they were being observed, but he didn’t seem entirely convinced by his own idea.
Imped
Definition:
(imp. & p. p.) of Imp
Example Sentences:
(1) Intramembrane particles (IMP) were quantitatively assessed in the perikaryal plasma membranes of infundibular neurons.
(2) The inhibition by TAD of IMP DH activity in ovarian carcinomas (N = 4) was 81%.
(3) Incubation of I diaphragms with isoproterenol did not significantly increase the concentrations of AMP, IMP or inorganic phosphate, activators of phosphorylase beta activity, nor was there a decrease in ATP and glucose 6-phosphate content, allosteric inhibitors of phosphorylase beta activity.
(4) Second, interconversion of adenine nucleotides to guanine nucleotides, is curtailed by the inhibition of IMP dehydrogenase by these same IMP analogues.
(5) Under optimal reaction conditions, HhaI and RsaI cleaved the DMTS-std duplex to 76-77% completion and the DMTS-imp duplex to 96-99% completion.
(6) The incorporation of inosine or hypoxanthine into the IMP and ITP has been proved.
(7) At all times, a tight inverse correlation exists between ATP and IMP concentrations.
(8) It was concluded that the IMP content of human skeletal muscle is very low at rest and after low-intensity exercise, but increases after moderate and high-intensity exercise.
(9) The synthetic "C" nucleoside, tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide), its selenium analogue selenazofurin, and the related inhibitor of inosine 5'-phosphate (IMP) dehydrogenase, mycophenolic acid, are effective inducers of the terminal differentiation of HL-60 promyelocytic leukemia cells.
(10) After 60 min recovery, exercise was performed for 8-10 min each at 20, 30, 40 and 50 W. Measurements of pulmonary oxygen uptake, heart rate, blood pressure, leg blood flow, and femoral arterial-venous differences of oxygen content and lactate were performed as well as determination of ATP, creatine phosphate (CP) inosine monophosphate (IMP) and lactate concentrations on biopsy material from the quadriceps muscle before and immediately after the intense exercise, and at 3, 10 and 60 min into recovery.
(11) Virazole 5'-phosphate was subsequently found to be a potent competitive inhibitor of inosine 5'-phosphate dehydrogenase (IMP:NAD(+) oxidoreductase, EC 1.2.1.14) isolated from Escherichia coli (K(m) = 1.8 x 10(-5) M) with a K(i) of 2.7 x 10(-7) M. Guanosine 5'-phosphate (GMP) was a competitive inhibitor of this enzyme with a K(i) of 7.7 x 10(-5) M. Virazole 5'-phosphate was similarly active against IMP dehydrogenase isolated from Ehrlich ascites tumor cells, with a K(i) of 2.5 x 10(-7) M. The K(m) for this enzyme was 1.8 x 10(-5) M, and the K(i) for GMP was 2.2 x 10(-4) M. These results suggest that the antiviral activity of Virazole might be due to the inhibition of GMP biosynthesis in the infected cell at the step involving the conversion of IMP to xanthosine 5'-phosphate.
(12) Initial rate kinetic studies demonstrate the ppGpp inhibition is competitive with respect to GTP and noncompetitive with respect to L-aspartate and IMP.
(13) Uptake of IMP was calculated from the arteriovenous difference of 14C-IMP across the lung and lung effluents and homogenates were analyzed for the presence of metabolites of IMP.
(14) During continuous isometric exercise with constant stimulation time, the amount of IMP was linearly and inversely related to the age of the animals; a higher IMP concentration was found in intermittent isometric and dynamic exercise.
(15) We evaluated the effect of high partial pressures of O2 on pulmonary uptake and metabolism of IMP.
(16) Thus, 123I-IMP and 99mTc-HM-PAO SPECTs seemed to be a useful tool in the diagnosis, deciding of whether the treatment was suspended or continued, and clarifying the pathophysiology in HSE.
(17) It was considered that the analysis of the lung release of 123I-IMP forms a new lung dysfunction index.
(18) The increased activity in cancer cells of inosine 5'-monophosphate dehydrogenase (IMP DH, EC 1.1.1.205), the rate-limiting enzyme of de novo GTP biosynthesis, was suggested as a sensitive target for chemotherapy.
(19) To determine the biochemical mechanisms of cytotoxicity of these drugs, assay procedures have been developed for measurement of the levels of intermediates proximal to IMP in the pathway for de novo purine biosynthesis in mouse L1210 leukemia cells.
(20) Our review indicates that 123I-IMP SPECT may have an important future role in the early diagnosis and management of patients with acute infarctive stroke and AD.