(n.) The creaking of a door, or a noise resembling it.
(n.) A painful, spasmodic affection of the muscles of some part of the body, as of the neck or back, rendering it difficult to move the part.
(n.) A small jackscrew.
Example Sentences:
(1) This suggests that (AGG)12 can form intra- and inter-molecular complexes by non-Watson-Crick, guanine:guanine base-pairing.
(2) It is demonstrated that this peculiar DNA fragment, under suitable conditions of concentration, salt and temperature, exclusively prefers to adopt a monomeric hairpin form with a stem of three Watson-Crick type base pairs and a loop of two residues.
(3) Hope u feel better xx” Bird told Channel 4’s political editor Michael Crick: “Natasha Bolter and I were in a consensual relationship between 18 September and 2 November, well after her admission to the list of approved candidates.
(4) The new Francis Crick Institute in London, now filling with 1,400 scientists, could be built and run for 10 years on that.
(5) The Watson-Crick H-bonded imino proton resonances were studied.
(6) The Watson-Crick alignment of the alkylG.T and alkylT.G mispairs may facilitate formation of these phosphodiester links, and this alignment rather than the strength of the base pairs and the extent of hydrogen bonding between them may be the crucial factor in the miscoding.
(7) The complex has one drug molecule intercalated between Watson--Crick base pairs of the nucleotide duplex.
(8) Recognition of the UACUAAC box thus relies, at least in part, on Watson-Crick base pairing with the yeast U2 analogue.
(9) A characteristic of Watson-Crick paired A X T and G X C bases is the pseudo 2-fold symmetry axis in the plane of the base pairs.
(10) The imino proton of T3 in the O6meG.T 12-mer and G3 in the O6meG.N 12-mer helix, which are associated with the modification site, resonate at unusually high field (8.5 to 9.0 ppm) compared to imino protons in Watson-Crick base pairs (12.5 to 14.5 ppm).
(11) We’d get recognised when we went out, and I developed a bad crick in my spine because I was staring at the pavement so much.
(12) The base pairing between piA and poly(U) in this system is probably of the Hoogsteen type (involving the 6-amino group and N7 of 3-isoadenosine) rather than of the Watson-Crick type.
(13) One of these models is a four-strand structure in which two duplexes of the Watson-Crick kind are specifically related by a twofold rotation axis and which has already been discussed in some detail.
(14) Nurse, too, believes the Crick is built on solid foundations.
(15) Molecular modeling shows that a stereochemically satisfactory structure can be build using C2'-endo sugars and a displacement of the Watson-Crick base-pair center from the helix axis of 2.5 A. Helical constraints of rise per residue (h = 3.26 A) and residues per turn (n = 12) were taken from fiber diffraction experiments of Arnott and Selsing (1974).
(16) The temperature variation of the imino proton NMR signals suggests that the hydrogen bonding in self-recognition is comparable in strength with that in a beta-DNA duplex, and NOE data are in accord with Watson-Crick rather than Hoogsteen base pairing.
(17) We describe NMR studies at superconducting fields which characterize aspects of the structure and stability of the 1 : 2 actinomycin-d-pG-C complex in solution as monitored at the Watson-Crick base pairs and backbone phosphate groups.
(18) From fibre diffraction data, models for triplex structures with poly(U).poly(A).poly(U) and poly(dT).poly(dA).poly(dT) have been proposed, in which the purine and one pyrimidine strand are Watson-Crick paired in an A' helix, and the other pyrimidine strand is Hoogsteen base-paired parallel to the purine strand along the major groove.
(19) The peptide forms a parallel, two-stranded coiled coil of alpha helices packed as in the "knobs-into-holes" model proposed by Crick in 1953.
(20) 7.09pm: On his blog, Newsnight's Michael Crick quotes an unnamed Liberal Democrat MP who told him he was amazed how much the Tories were willing to compromise.
Sprain
Definition:
(v. t.) To weaken, as a joint, ligament, or muscle, by sudden and excessive exertion, as by wrenching; to overstrain, or stretch injuriously, but without luxation; as, to sprain one's ankle.
(n.) The act or result of spraining; lameness caused by spraining; as, a bad sprain of the wrist.
Example Sentences:
(1) After the diagnosis of a soft-tissue injury (sprain, strain, or contusion) has been made, treatment must include an initial 24- to 48-hour period of RICE.
(2) The distinction between a benign and a severe ligamentous sprain may thus be made.
(3) Arthrography was assessed in 61 cases of recurrent lateral sprains of the ankle more than 2 weeks after acute injury; 38 were considered as positive.
(4) Medial collateral sprains are produced primarily by external rotation and valgus forces.
(5) Thus, prevention of ankle sprains may be by modification of any of these factors.
(6) Rest, ice therapy, compression, and elevation (RICE) are important components of the initial management of acute soft-tissue injuries such as contusions, strains, and sprains.
(7) This lesion is usually associated with ankle trauma, such as lateral ankle sprains, ruptures of the fibular collateral ligaments, and transchondral fractures of the talar dome.
(8) We conclude that the use of weighted radiographs lacks efficacy in unmasking grade 3 AC sprains on radiograph and we recommend that routine use of this technique be abandoned.
(9) In general, sprains and strains account for 40% of injuries, contusions 25%, fractures 10%, concussions 5% and dislocations 15%.
(10) The purpose of this study was to investigate postural responses of healthy subjects and patients with recent ankle sprains following a perturbation that created sway in the frontal plane.
(11) Most injuries were contusions (35.9%), followed by strains or sprains (28.2%), epistaxis (12.8%), lacerations (5.1%), and one finger fracture (2.6%), the most significant injury.
(12) In conclusion, diclofenac potassium has been demonstrated to be effective in the treatment of acute ankle sprains and it had a rapid onset of action and good tolerability.
(13) The purpose of the study was to determine the long-term healing potential of nonoperatively treated isolated sprains of the medial collateral ligament (MCL) of the knee joint.
(14) The most common injury types were lacerations (33%), contusions and abrasions (22%), sprains (16%), and fractures (13%).
(15) In thermographic control studies of temperature profiles legs of 93 patients with a sprained ankle temperature phenomenon was observed, which super-imposes the hyperthermia due to inactivity.
(16) While the morbidity (fractures, strains, sprains, and occasionally more severe injuries) associated with skiing is well recognized and considered by most physicians concerned to be distributed somewhat unevenly within the various skills of skiing, the authors have identified an exceedingly low mortality among the same population.
(17) The "pronation worm", a method of early functional active conservative treatment for sprained ankle, is presented.
(18) These studies suggest that positioning the ankle in dorsiflexion instead of neutral or plantar flexion may have advantages in promoting a stable ankle if immobilization is chosen for treating a grade III sprain.
(19) The treatment of serious sprains and chronic laxity of the knee calls for a knowledge of the mechanical properties of the stabilizing structures.
(20) Girls had more sprains (P less than 0.001) but fewer contusions and wounds (P less than 0.001).