(a.) Having the form of a cross; appertaining to a cross; cruciform; intersecting; as, crucial ligaments; a crucial incision.
(a.) Severe; trying or searching, as if bringing to the cross; decisive; as, a crucial test.
Example Sentences:
(1) Therefore, the measurement of the alpha-antitrypsin content plays the crucial part in differential diagnosis of primary (hereditary determined) and secondary (obstructive) emphysema.
(2) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
(3) The agriculture ministry raised the risk level of the virus spreading from moderate to high on Tuesday across the country, at a crucial time for the industry.
(4) Conservative commentators responded with fury to what they believed was inappropriate meddling at a crucial moment in the town hall debate.
(5) Although the performance aspects of electronic displays are crucial considerations in workstation design, experience suggests that human factors in mechanical operation, software accessibility, and workstation environment are also important.
(6) The secretary of state should work constructively with frontline staff and managers rather than adversarially and commit to no administrative reorganisation.” Dr Jennifer Dixon, chief executive, Health Foundation “It will be crucial that the next government maintains a stable and certain environment in the NHS that enables clinical commissioning groups (CCGs) to continue to transform care and improve health outcomes for their local populations.
(7) The results suggest that the ACTH-containing part of the hypothalamus around the PVH is crucially involved in the organization of grooming behaviour.
(8) A functional impairment of the amino acid transport systems at the level of the blood-brain barrier seems to play a crucial role in causing deleterious modifications of the synaptic neurotransmission in the central nervous system.
(9) The cerebral distribution and regulation of excitatory amino acid levels may play a crucial role in neuronal development.
(10) Imagining faces was also the only condition that led to an increase of activity in the left inferior occipital region which has been suggested by previous studies as being a crucial area for visual imagery.
(11) This is the most crucial issue of our time and the people must be heard, not criminalised."
(12) Therefore it is crucial to investigate the role of glucocorticoids in non-pituitary tumours and this requires an understanding of the molecular mechanisms involved in glucocorticoid inhibition of the normal POMC gene in the pituitary.
(13) The agreement, hailed as a "landmark" deal and a breakthrough by politicians and the green lobby alike, came before a crucial EU summit opening in Brussels tomorrow at which 27 prime ministers and presidents are supposed to finalise an ambitious package to cut greenhouse gas emissions by 20% by 2020.
(14) A comparison of the pharmacokinetics as well as the teratogenicity between cyclophosphamide and some specific deuterium-labeled analogues showed that the isotope effect observed can be related to a particular metabolic pathway crucial for teratogenic activation by this drug.
(15) The crucial issue of whether subtle behavioral, intellectual, and developmental impairment occurs in young children, as a result of lead-induced CNS damage is discussed in detail.
(16) The crucial point in all likelihood is the nature of this heme-binding protein.
(17) Standard criteria for staging and response evaluation, including pathologic documentation of remission status, are crucial.
(18) Given that a post-poll economy still registers as a crucial issue among undecided voters, and that matters economic are now his BBC day job, that was hardly surprising.
(19) Overall, these results confirm that the medial septum plays a crucial role in the acquisition of problem solving.
(20) He is joined by Cathy O’Toole, the ALP candidate for the crucial swing seat of Herbert where Rudd’s campaign bus has stopped on Sunday evening.
Important
Definition:
(v. t.) Full of, or burdened by, import; charged with great interests; restless; anxious.
(v. t.) Carrying or possessing weight or consequence; of valuable content or bearing; significant; weighty.
(v. t.) Bearing on; forcible; driving.
(v. t.) Importunate; pressing; urgent.
Example Sentences:
(1) CT appears to yield important diagnostic contribution to preoperative staging.
(2) This paper discusses the typical echocardiographic patterns of a variety of important conditions concerning the mitral valve, the left ventricle, the interatrial and interventricular septum as well as the influence of respiration on the performance of echocardiograms.
(3) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(4) Glucocorticoids have numerous effects some of which are permissive; steroids are thus important not only for what they do, but also for what they permit or enable other hormones and signal molecules to do.
(5) Trifluoroacetylated rabbit serum albumin was 5 times more reactive with these antibodies and thus more antigenic than the homologous acetylated moiety confirming the importance of the trifluoromethyl moiety as an epitope in the immunogen in vivo.
(6) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(7) However it is important to recognize these cysts so that correct surgical management is offered to the patient.
(8) gamma-Aminobutyric acid (GABA) and glutamate release from the treated side was higher than the control value during the first 2-3 h, a result indicating an important role of glial cells in the inactivation of released transmitter.
(9) Under blood preservation conditions the difference of the rates of ATP-production and -consumption is the most important factor for a high ATP-level over long periods.
(10) This finding is of major importance for persons treated with diltiazem who engage in sport.
(11) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(12) Because of the dearth of epidemiological clues as to causation, studies with experimental animal models assume greater importance.
(13) The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM).
(14) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(15) Nutritional factors or environmental toxins have important effects on CNS degenerative changes.
(16) Moreover, homozygous deletion of the FMS gene may be an important event in the genesis of the MDS variant 5q- syndrome.
(17) Importantly, these characteristics were strong predictors of subsequent mortality.
(18) As the requirements to store and display these images increase, the following questions become important: (a) What methods can be used to ensure that information given to the physician represents the originally acquired data?
(19) Periosteal chondroma is an uncommon benign cartilagenous lesion, and its importance lies primarily in its characteristic radiographic and pathologic appearance which should be of assistance in the differential diagnosis of eccentric lesions of bones.
(20) As important providers of health care education, nurses need to be fully informed of the research findings relevant to effective interventions designed to motivate health-related behavior change.