(v. i.) To reach its highest point of altitude; to come to the meridian; to be vertical or directly overhead.
(v. i.) To reach the highest point, as of rank, size, power, numbers, etc.
(a.) Growing upward, as distinguished from a lateral growth; -- applied to the growth of corals.
Example Sentences:
(1) Beckham's decision marks the culmination of a strategy aimed at preserving his brand long after the footballer has faded.
(2) A hypothetical scheme is presented that pursues the processes involved in invasion from the biochemical events generated by attachment of the parasite, to the steric rearrangement of red cell membrane proteins, which culminates in invasion.
(3) He'd later carry this over into Netflix's House Of Cards but before that, TV had already begun to emulate this new, bleak, antiheroic maturity with a cycle of dark, longform, acclaimed dramas, commencing with The Sopranos and culminating in Breaking Bad .
(4) Fox will be accompanied by the sporting director, Hendrik Almstadt, on the back of the 1-1 draw against Wycombe Wanderers in the FA Cup on Saturday, when their failure to beat a League Two side culminated in angry scenes involving the away supporters.
(5) It was found that: the two cell types have the same basal adenylate cyclase activity; prespore cells and prestalk cells are able to relay the extracellular cAMP signal equally well; intact prestalk cells show a threefold higher cAMP phosphodiesterase activity on the cell surface than prespore cells, whereas their cytosolic activity is the same; intact prestalk cells bind three to four times more cAMP than prespore cells; no large differences in cAMP metabolism and detection were observed between cells derived from migrating slugs and culminating aggregates.
(6) Despite a dreadful end to last season, culminating in a 6-1 defeat at Stoke City, FSG are pressing ahead with transfer plans agreed with Rodgers, indicating the manager’s position is safe at the moment.
(7) After standardized observation of mating behavior culminating in ejaculation and a sperm plug, females were allowed to produce litters in undisturbed conditions.
(8) As culmination proceeds, pstA cells transform into pstB cells by activating the ecmB gene as they enter the stalk tube.
(9) Significant numbers of PFC were encountered in the spleen as early as 14 to 18 hours after a single intravenous injection of antigen; after 36 hours the number of PFC rose rapidly and culminated in a maximum population at 5 days, followed by a rapid decline and plateau similar to that for circulating antibody.
(10) Richard Betts, a climate expert at the Meteorological Office and one of about 130 senior authors of Friday's report, said: "This is the culmination of three years' work.
(11) It will feature in meetings of the G8 group of industrialised countries, and the Tokyo international conference on African development, culminating in the Brussels meeting on the new deal for fragile states.
(12) At the culmination of each molt, the larval tobacco hornworm exhibits a pre-ecdysis behavior prior to shedding its old cuticle at ecdysis.
(13) This diplomatic battle culminated last year in the signing of a peace agreement between the rebels and the government which imposed an immediate ceasefire, and was supposed to lead to a government of national unity with Machar once again in the vice-president’s office.
(14) Several lines of experimental evidence suggest that an anterior-posterior gradient of cyclic AMP exists in migrating pseudoplasmodia of the cellular slime mold Dictyostelium discoideum, and that this gradient may be responsible for control of the proportions of stalk and spore cells that form during culmination.
(15) The Hanover action was, she says, the culmination of years of protests and training, the result of tactics that have evolved from action to action.
(16) But relations have steadily improved, as did the Vatican’s influence, culminating in last December’s deal with the US.
(17) His comic adventures are too many to relate, but it may be said that they culminate in a café of 'singing waiters' where, after a wealth of comic 'business' with the tray, he shows his disdain for articulate speech by singing a vividly explicit song in gibberish.
(18) Enzyme activity in developing spore cells increased 10-fold during differentiation from myxamoebae (0 h) to the culmination stage (20 h) and decreased slightly at sorocarp (24 h).
(19) In 1993, at the Branch Davidian religious compound outside Waco, Texas, the Bureau of Alcohol, Tobacco and Firearms didn’t wait for the sect leader, David Koresh, to leave before attempting to arrest him and got into a gun battle that claimed 10 victims and led to a disastrous 51-day siege culminating in dozens more deaths.
(20) We propose a model whereby a protein repressor, under the control of PKA, inhibits precocious induction of stalk cell differentiation by DIF and so regulates the choice between slug migration and culmination.
Terminate
Definition:
(v. t.) To set a term or limit to; to form the extreme point or side of; to bound; to limit; as, to terminate a surface by a line.
(v. t.) To put an end to; to make to cease; as, to terminate an effort, or a controversy.
(v. t.) Hence, to put the finishing touch to; to bring to completion; to perfect.
(v. i.) To be limited in space by a point, line, or surface; to stop short; to end; to cease; as, the torrid zone terminates at the tropics.
(v. i.) To come to a limit in time; to end; to close.
Example Sentences:
(1) The amino acid sequence deduced from the nucleotide sequence contained both amino- and carboxyl-terminal sequences.
(2) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(3) We have examined the insertion of bovine 17 alpha-hydroxylase (P45017 alpha) into the endoplasmic reticulum of COS 1 cells to evaluate the functional role of its hydrophobic amino-terminal sequence and membrane insertion.
(4) The use of glucagon in double-contrast studies of the colon has been recommended for various reasons, one of which is to facilitate reflux of barium into the terminal ileum.
(5) Amino acid sequence analysis showed that both peaks had identical N-terminal sequences through the first 28 residues.
(6) Plasma NPY correlated better with plasma norepinephrine than with epinephrine, indicating its origin from sympathetic nerve terminals.
(7) As a group, the three mammalian proteins resemble bovine serum conglutinin and behave as lectins with rather broad sugar specificities directed at certain non-reducing terminal N-acetylglucosamine, mannose, glucose and fucose residues, but with subtle differences in fine specificities.
(8) In the caudal spinal trigeminal nucleus (Vc), the collaterals of one half of the periodontium afferent fibers terminated mainly in lamina V at the rostral and middle levels of Vc.
(9) The amino-terminal region of a 70 kDa mitochondrial outer membrane protein of yeast and the presequence of cytochrome c1, an inner membrane protein exposed to the intermembrane space, are thought to be responsible for localizing the proteins in their final destinations after synthesis in the cytosol.
(10) The mtRF-1 could translate all of the known termination codons in the rat mitochondrial genome.
(11) However, none of the nerve terminals making synaptic contacts with glomus cells exhibited SP-like immunoreactivity.
(12) The B cell epitopes included regions of transition between the more hydropathic (including the N-terminal end of the F1 and F2 protein) and hydrophilic sequences.
(13) Somatostatin-like immunoreactivity has been found to occur in nerve terminals and fibres of the normal human skin using immunohistochemistry.
(14) The seve polypeptide chains investigated had generalyy similar properties; all contained two residues per molecule of tryptophan and N-acetylserine was the common N-terminal amino acid residue.
(15) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
(16) The presence of a few key residues in the amino-terminal alpha-helix of each ligand is sufficient to confer specificity to the interaction.
(17) The earliest degenerative changes were seen in sensory and motor terminals at 20-24 h after the lesion.
(18) The terminal half-life averaged 12 h following intravenous and 15 h after oral administration.
(19) A retrospective study examined the reactions to the termination of pregnancy for fetal malformation and the follow up services that were available.
(20) A reduction in neonatal deaths from this cause might be expected if facilities for antenatal diagnosis and termination of pregnancy were made available, although this raises grave ethical problems.