(n.) The attainment of the highest point of altitude reached by a heavently body; passage across the meridian; transit.
(n.) Attainment or arrival at the highest pitch of glory, power, etc.
Example Sentences:
(1) Beckham's decision marks the culmination of a strategy aimed at preserving his brand long after the footballer has faded.
(2) A hypothetical scheme is presented that pursues the processes involved in invasion from the biochemical events generated by attachment of the parasite, to the steric rearrangement of red cell membrane proteins, which culminates in invasion.
(3) He'd later carry this over into Netflix's House Of Cards but before that, TV had already begun to emulate this new, bleak, antiheroic maturity with a cycle of dark, longform, acclaimed dramas, commencing with The Sopranos and culminating in Breaking Bad .
(4) Fox will be accompanied by the sporting director, Hendrik Almstadt, on the back of the 1-1 draw against Wycombe Wanderers in the FA Cup on Saturday, when their failure to beat a League Two side culminated in angry scenes involving the away supporters.
(5) It was found that: the two cell types have the same basal adenylate cyclase activity; prespore cells and prestalk cells are able to relay the extracellular cAMP signal equally well; intact prestalk cells show a threefold higher cAMP phosphodiesterase activity on the cell surface than prespore cells, whereas their cytosolic activity is the same; intact prestalk cells bind three to four times more cAMP than prespore cells; no large differences in cAMP metabolism and detection were observed between cells derived from migrating slugs and culminating aggregates.
(6) Despite a dreadful end to last season, culminating in a 6-1 defeat at Stoke City, FSG are pressing ahead with transfer plans agreed with Rodgers, indicating the manager’s position is safe at the moment.
(7) After standardized observation of mating behavior culminating in ejaculation and a sperm plug, females were allowed to produce litters in undisturbed conditions.
(8) As culmination proceeds, pstA cells transform into pstB cells by activating the ecmB gene as they enter the stalk tube.
(9) Significant numbers of PFC were encountered in the spleen as early as 14 to 18 hours after a single intravenous injection of antigen; after 36 hours the number of PFC rose rapidly and culminated in a maximum population at 5 days, followed by a rapid decline and plateau similar to that for circulating antibody.
(10) Richard Betts, a climate expert at the Meteorological Office and one of about 130 senior authors of Friday's report, said: "This is the culmination of three years' work.
(11) It will feature in meetings of the G8 group of industrialised countries, and the Tokyo international conference on African development, culminating in the Brussels meeting on the new deal for fragile states.
(12) At the culmination of each molt, the larval tobacco hornworm exhibits a pre-ecdysis behavior prior to shedding its old cuticle at ecdysis.
(13) This diplomatic battle culminated last year in the signing of a peace agreement between the rebels and the government which imposed an immediate ceasefire, and was supposed to lead to a government of national unity with Machar once again in the vice-president’s office.
(14) Several lines of experimental evidence suggest that an anterior-posterior gradient of cyclic AMP exists in migrating pseudoplasmodia of the cellular slime mold Dictyostelium discoideum, and that this gradient may be responsible for control of the proportions of stalk and spore cells that form during culmination.
(15) The Hanover action was, she says, the culmination of years of protests and training, the result of tactics that have evolved from action to action.
(16) But relations have steadily improved, as did the Vatican’s influence, culminating in last December’s deal with the US.
(17) His comic adventures are too many to relate, but it may be said that they culminate in a café of 'singing waiters' where, after a wealth of comic 'business' with the tray, he shows his disdain for articulate speech by singing a vividly explicit song in gibberish.
(18) Enzyme activity in developing spore cells increased 10-fold during differentiation from myxamoebae (0 h) to the culmination stage (20 h) and decreased slightly at sorocarp (24 h).
(19) In 1993, at the Branch Davidian religious compound outside Waco, Texas, the Bureau of Alcohol, Tobacco and Firearms didn’t wait for the sect leader, David Koresh, to leave before attempting to arrest him and got into a gun battle that claimed 10 victims and led to a disastrous 51-day siege culminating in dozens more deaths.
(20) We propose a model whereby a protein repressor, under the control of PKA, inhibits precocious induction of stalk cell differentiation by DIF and so regulates the choice between slug migration and culmination.
Zenith
Definition:
(n.) That point in the visible celestial hemisphere which is vertical to the spectator; the point of the heavens directly overhead; -- opposed to nadir.
(n.) hence, figuratively, the point of culmination; the greatest height; the height of success or prosperity.
Example Sentences:
(1) The Cambridge-based couple felt ignored when tried to raise the alarm about the way their business – publisher Zenith – was treated by Lynden Scourfield, the former HBOS banker jailed last week, and David Mills’ Quayside Corporate Services.
(2) After 24 h of fasting the zenith was shifted to the beginning of dark period without any other changes.
(3) Clinical electroencephalography, which reached a zenith in the 1950s and 1960s, increased the range of diagnostic techniques available for a series of brain diseases and revolutionized the study of epilepsy.
(4) That triumphal speech was his apex, the acme, the zenith of his career.
(5) The circadian rhythm of PRL persisted throughout lactation as manifested by: (1) significantly higher mean nighttime than daytime PRL levels in the whole sample, despite higher daytime nursing durations; (2) the distribution of zenith levels which most frequently occur between 23.00 and 07.00 h, when nursing duration is lowest, and which are almost absent between 07.00 and 23.00 h, when nursing duration is highest, and of nadir levels, which have an opposite pattern; (3) spontaneous PRL surges that are more frequent, longer, and of higher magnitude at night than during the day, and (4) the larger magnitude of suckling-induced PRL release from late afternoon through the night compared to the morning in some women.
(6) The zeniths of the curves were recorded about 4--6 hours after the skin incision in both patient groups, despite the different duration of the operations.
(7) However, 1990 proved to be not only the Indy's circulation zenith but also a watershed for its publishing company as recession bit hard into revenue.
(8) After 48 h of fasting remarkable shifts were found resulting in a nadir at the beginning of dark period and a zenith at the middle of light period.
(9) The dying have much to teach the living: so in many ways, this project is the zenith of the Big Brother experiment.
(10) The kind of cinema that reached a zenith in Gillo Pontecorvo's Battle of Algiers .
(11) The cercal system, which may have evolved with the first terrestrial hexapods, reaches its zenith in the orthopteroid insects, but was replaced in holometabolan insects by visual startle mechanisms with descending giant interneurons.
(12) Population growth reached its zenith between 1950-70.
(13) We detected a consistent and significant (P less than 0.01) decline in plasma chromium after glucose administration, the nadir of the chromium response coinciding with the zenith of the glucose concentration.
(14) Thus, the ED30s constitute the "zenith" of an independent isobole in ED50 isobolograms.
(15) They reached a zenith during the Vietnam war when the US government allegedly conducted their highly classified Operation Popeye, an attempt to extend the monsoon season by cloud seeding in the hope of flushing out the Viet Cong.
(16) On Sunday, Mélenchon's star reached its zenith, when early results gave him 11.1% of votes, several percentage points lower than had been expected.
(17) Whereas phosphate has a marked circadian rhythmicity with a zenith between 1.00 and 8.00 hours, total calcium and albumin show a tendency to decrease between 20.00 and 6.00 hours.
(18) The zenith of suppressor activity was observed during most active infection, from 1 to 3 weeks after inoculation.
(19) At the zenith of a culture war, there’s seldom room for compromise.
(20) The highest pressures in the series (about 4 to 5 megaNewtons per square metre) were on the areas of thin fibrocartilage which were identified at the zenith of certain acetabula.