(a.) Characterized by mental and moral training; disciplined; refined; well-educated.
Example Sentences:
(1) After stimulation with lipopolysaccharide and calcium ionophore A23187, culture supernatants of clones c18A and c29A showed cytotoxic activity against human melanoma A375 Met-Mix and other cell lines which were resistant to the tumor necrosis factor, lymphotoxin and interleukin 1.
(2) If ascorbic acid was omitted from the culture medium, the extensive new connective tissue matrix was not produced.
(3) He is also the foremost theorist of the Tijuana-San Diego border in terms of what happens when the urban culture of the developing world collides with that of the developed world.
(4) Our data suggest that a rational use of surveillance cultures and serological tests may aid in an earlier diagnosis of FI in BMT patients.
(5) In attacking the motion to freeze the licence fee during today's Parliamentary debate the culture secretary, Andy Burnham, criticised the Tory leader.
(6) The extent of the infectious process was limited, however, because the life span of the cultures was not significantly shortened, the yields of infectious virus per immunofluorescent cell were at all times low, and most infected cells contained only a few well-delineated small masses of antigen, suggestive of an abortive infection.
(7) It involves creativity, understanding of art form and the ability to improvise in the highly complex environment of a care setting.” David Cameron has boosted dementia awareness but more needs to be done Read more She warns: “To effect a cultural change in dementia care requires a change of thinking … this approach is complex and intricate, and can change cultural attitudes by regarding the arts as central to everyday life of the care home.” Another participant, Mary*, a former teacher who had been bedridden for a year, read plays with the reminiscence arts practitioner.
(8) Rapid overgrowth of all cultures with the E. coli necessitated the use of selective media containing antimicrobial agents to which the E. coli was sensitive.
(9) Patient or fetal cord serum is commonly used as a protein supplement to culture media used in in-vitro fertilization (IVF).
(10) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(11) We have developed a new procedure for the rapid preparation of undegraded total RNA from cultured cells for specific quantitation by dot blotting analysis.
(12) A simple method for ultrarapid freezing of cell cultures in monolayers was developed.
(13) The results indicate that OA-bearing macrophages primed T cells and generated helper T cells, whereas the culture of normal lymphocytes with soluble OA in the absence of macrophages generated suppressor T cells.
(14) The effects of phenoxyacetic acid herbicides were investigated on the induction of chromosome aberrations in human peripheral lymphocyte cultures in vitro and in lymphocytes of exposed workers in vivo.
(15) Small pieces of anterior and posterior quail wing-bud mesoderm (HH stages 21-23) were placed in in vitro culture for up to 3 days.
(16) Human gingival fibroblasts were allowed to attach and spread on bio-glasses for 1-72 h. Unreactive silica glass and cell culture polystyrene served as controls.
(17) However, further improvement of culture systems is needed for active replication of HBV in vitro.
(18) This paper has considered the effects and potential application of PFCs, their emulsions and emulsion components for regulating growth and metabolic functions of microbial, animal and plant cells in culture.
(19) Cells (1 x 10(5)) were seeded in 12- x -75-mm tissue culture tubes and incubated with various doses of IL-1 beta, IL-1 alpha, TNF-alpha, and IFN-gamma, alone or in specific combinations, for 15 min, two, 12, 24, and 72 h. PGE concentrations in the media were measured by radio-immunoassay.
(20) This activation demonstrated in humans confirms the pharmacological results of the interferon induction obtained with SL04 in vivo in mice and in vitro in human cell cultures.
Sophisticated
Definition:
(imp. & p. p.) of Sophisticate
(a.) Adulterated; not pure; not genuine.
Example Sentences:
(1) "With the advent of sophisticated data-processing capabilities (including big data), the big number-crunchers can detect, model and counter all manner of online activities just by detecting the behavioural patterns they see in the data and adjusting their tactics accordingly.
(2) A developing sophistication on the part of both children and parents, coupled with a rapidly expanding recognition of the need to minimize the amount of physical and psychological trauma that a child has to experience, has led to a growing use of premedication agents for children.
(3) The initial defect can be directly measured by glucose clamp and other sophisticated techniques; the clinical syndrome may be derived from a network of related variables known to be associated with reduced insulin action.
(4) While simple assays of complex I activity are unlikely to be useful in the preclinical detection of Parkinson's disease, other more sophisticated physical-chemical approaches including detection of free radical damage may have utility.
(5) This is not some sophisticated, Westminstery battle, but a life-and-death, misery-or-decency choice about the very basics of life for hundreds of thousands of older British people.
(6) While the high sophistication subjects rated the interpretation as accurate across validity conditions, the low sophistication subjects rated the interpretation according to the validity instructions they received.
(7) Lateralization may be an expression of reflex constraints bound initially to the infant's tonic-neck posture, with later development less reflex-patterned during the acquisition of more sophisticated information-processing strategies.
(8) A simple multiband volume control is expected to provide much of the benefit of more sophisticated systems without the need for separate estimation of input speech and noise spectra.
(9) What’s imperative from an organizational standpoint, he added, is “understanding where voters are, what their concerns are, and building a sophisticated operation around that.
(10) The laws of functioning applicable to these approaches are those coming from liberal and planified economical theories while health planning has developed more and more sophisticated and convincing methodologies.
(11) Therefore, controlled hypotension, being a sophisticated technique, requires handling by an experienced anesthetist well aware of contraindications and the need for adequate monitoring for prevention of tissue ischemia.
(12) However, a homemade pipe bomb thrown at a police patrol in north Belfast earlier this year was described as of a new, sophisticated variety that the PSNI had not seen before.
(13) While numerous studies on infant perception have demonstrated the infant's ability to discriminate sounds having different frequencies, little research has evaluated more sophisticated pitch perception abilities such as perceptual constancy and perception of the missing fundamental.
(14) It is concluded that imaging of the urinary tract is not necessary for pure nightwetters, while ultrasonography or uroflowmetry and more sophisticated radiological or urological methods should be focused on those children with daytime wetting and clinical symptoms of voiding disturbances.
(15) When multiple database systems are present, a flexible front end can provide sophisticated querying capabilities that bridge the systems, while hiding the complexities of the multiple systems from the user.
(16) This validity coefficient turned out to be so high (r = 0.967) that it does not seem necessary to adopt a more sophisticated method, despite a few demonstrable shortcomings of the one in use.
(17) The comparison of drug responder and non-responder group has also been made more meaningful by the availability of more reliable methods of assessing clinical phenomena, more sophisticated diagnostic models and the introduction of other biological measures.
(18) The environment in the intensive therapy units (ITUs) has thus become increasingly sophisticated with the use of highly specialised equipment.
(19) Attempts to save parts of teeth go back 100 years or more, but it is the increased predictability of success of endodontic therapy and the increased sophistication of periodontal treatment that have given us the means to save molars with furcation problems that, otherwise, would be lost.
(20) The monitoring equipment gets more sophisticated and easier to use month by month.