(v. t.) To cut into jags or points; to slash; as, to dag a garment.
(v. i.) To be misty; to drizzle.
Example Sentences:
(1) In general, optimal DAGAT activity in vitro was observed when long-chain unsaturated acyl-CoAs and diacylglycerols (DAGs) containing long acyl chains were used as substrates for in vitro TAG synthesis (although 1,2-didecanoin was also very effective).
(2) Incubation of microsomes with CDP-DAG of different fatty acid composition results in quantitative and qualitative differences in lysoPI formation.
(3) We now report that two synthetic diacylglycerols (DAG) replicate the stimulatory and inhibitory effects of TPA on frog skin.
(4) The distribution of PKC returned to control values by 24 h. High glucose did not stimulate phosphoinositide hydrolysis, as evidenced by the absence of an increase in the water-soluble inositol phosphates, indicating that DAG was not generated through the action of a phosphoinositide-specific phospholipase C. Cells treated with the cell-permeable DAG analogue 1-oleoyl-2-acetyl glycerol to activate PKC displayed approximately two-fold increases of fibronectin, laminin, and type IV collagen mRNA levels after normalization against actin.
(5) We observed a 30-45% increase in DAG in rat gastrocnemius and diaphragm muscles, 5-15 min after intramuscular or intravenous injections of 1-3 U of insulin per rat, doses which would be expected to activate insulin receptors more fully.
(6) Concomitantly, an increase of inositol phosphates and diacylglycerol (DAG) production was observed.
(7) The accumulation of [14C]C20:4-DAG (lower in ET than in saline-infused rats) was paralleled by a decrease in phosphatidylinositol (PI) labelling, whereas phosphatidic acid showed a transient increase by 5 min in saline- but not in ET-infused rats.
(8) To determine the role of the DAG produced upon bombesin stimulation, we examined the effects of another activator of protein kinase C, the phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA).
(9) It is concluded that carbachol increases [Ca2+]i by facilitating Ca2+ entry through L-type Ca2+ channels via a 1,2-diacylglycerol (DAG)-protein kinase C (PKC)-dependent pathway while quisqualate mobilizes Ca2+ from inositol 1,4,5-trisphosphate (IP3)-sensitive stores.
(10) In order to characterize the properties of the glyceroglycolipid membranes, ESR spectroscopic studies were carried out with an acyl spin-labeled galactosyl ceramide (SL-GC) or a headgroup spin-labeled phospholipid (SL-6-DPPA) in 1,2-dipalmitoyl[beta-cellobiosyl-(1'---3)]glycerol (Cel-DAG) liposomal membranes.
(11) The E. coli dgkA locus which contains the coding sequences for DAG kinase was subcloned into an eukaryotic expression vector, pMT2.
(12) The mean residence time for pharmacologically active molecules in the body was six times shorter for DAG (1.9 hr) than for DBD (11.4 hr).
(13) These data suggest that PKC is a mediator in the generation of DAG.
(14) These results suggest that DAG accumulation is involved in the potentiating effect of A23187 on CCh-stimulated amylase secretion.
(15) It is concluded that insulin-dependent PDH activation, PIG hydrolysis, and IG and DAG generation are mediated by the wild-type but not by the mutated insulin receptor of Val996.
(16) Since most alloantibodies detected only by 2SP-IAT or LISS-DAG were of doubtful clinical significance, and these techniques produced a high number of unwanted positive reactivities, we conclude that 2SP-IAT and LISS-DAG are not appropriate for the pretransfusion screening for unexpected antibodies.
(17) 261, 8597-8600), lipase from Rhizopus arrhizus selectively degraded the 1-acyl-containing species (DAG), but the ether lipid (EAG) was resistant and was identified and quantified after thin layer chromatography separation.
(18) 1-Oleoyl-2-acetylglycerol, a synthetic DAG analog, stimulated endothelial cell DNA synthesis in a concentration-dependent manner.
(19) Whereas DPG and DS are stable at physiological pH, DAG is unstable, undergoing hydrolysis (regeneration of DF) and rearrangement (intramolecular acyl migration to the 2-, 3- and 4-O-acyl-positional isomers).
(20) Addition of PRL to hepatocyte cultures significantly increased [3H]-glycerol incorporation into DAG within 5 minutes which was followed by a loss of cytosolic PKC activity by 10 minutes.
Dig
Definition:
(v. t.) To turn up, or delve in, (earth) with a spade or a hoe; to open, loosen, or break up (the soil) with a spade, or other sharp instrument; to pierce, open, or loosen, as if with a spade.
(v. t.) To get by digging; as, to dig potatoes, or gold.
(v. t.) To hollow out, as a well; to form, as a ditch, by removing earth; to excavate; as, to dig a ditch or a well.
(v. t.) To thrust; to poke.
(v. i.) To work with a spade or other like implement; to do servile work; to delve.
(v. i.) To take ore from its bed, in distinction from making excavations in search of ore.
(v. i.) To work like a digger; to study ploddingly and laboriously.
(n.) A thrust; a punch; a poke; as, a dig in the side or the ribs. See Dig, v. t., 4.
(v. t.) A plodding and laborious student.
Example Sentences:
(1) Its few remaining mines involve people digging coal out of hillsides.
(2) The satellite component is not found when digging up from the tube bottom.
(3) And stopping them means taking action in Syria, because it is Raqqa that is their headquarters .” Isis digging in amid intensified airstrikes in Raqqa, say activists Read more He added: “We shouldn’t be content with outsourcing our security to our allies.
(4) Who shot you in the back as you drove on your motorbike to dig your children out of the rubble?
(5) Things like digging in the garden often cause low back pain, and exercises will be good treatment for this.
(6) Its boot always held a bivouac bag, a trenching tool of some sort and a towel and trunks, in case he passed somewhere interesting to sleep, dig, or swim.
(7) "In high-value areas like London it can be worthwhile digging under the house to add a basement, but in other parts of the country it won't be worth it," says Helen Brunskill of Brunskill Design Architects.
(8) The conditions for the incorporation of digoxigenin-11-dUTP (dig-11-dUTP) during polymerization were optimized to generate strand specific DNA hybridization probes up to a length of 5000 nt.
(9) Dig-ASO testing correctly reclassified 10 individuals who had tested inconclusively on analysis for leukocyte beta-hexosaminidase A activity; 3 were identified as carriers and 7 as noncarriers.
(10) Before digging into the problems with this latest solution, one big acknowledgment must be made: this is about as big a step as the ECB could have taken.
(11) It tells you everything you need to know about a Russia digging in for another 12 years of Putin.
(12) Merkl says the plan is to “really dig into the economics of collection and recycling so that people will find it profitable to collect and to separate.
(13) The judge noted the “seriousness of these offences and impact on road traffic, particularly given the number of fines previously issued against BT by TfL for similar offences.” Firms undertaking work anywhere in London need a permit before digging up the roads, allowing highway authorities to coordinate work to minimise disruption.
(14) Fracking for shale gas involves digging, often as deep as a kilometre down, and pumping a mix of water, sand and chemicals into surrounding rock to fracture it and release the gas.
(15) This has been a really fascinating half of football: the favourites finally showing some real class up front, the minnows digging deep in defence and occasionally breaking forward.
(16) Dig deeper into the funding numbers – the real story of national politics in the post Citizens United age – and the Tea Party realignment of the GOP stands out yet more starkly.
(17) Welbeck's goal drought came to an end when Rafael da Silva wriggled clear on the right and managed to dig out a deep cross that the unmarked Adnan Januzaj, whom Moyes felt came in for some rough treatment, headed against the far post.
(18) Stephen Fisher, one of the archaeologists recording the site, says digging the trenches would also have been training for the men, who would soon have to do it for real, and the little slit trenches scattered across the site, just big enough for one man to cower in, might represent their first efforts.
(19) We do not need parliamentary inquiries or royal commissions to dig into this."
(20) "Landlords have a duty to give assured shorthold tenants at least two months' notice when evicting them," says Heather Kennedy of Digs.