(v. t.) To cut into jags or points; to slash; as, to dag a garment.
(v. i.) To be misty; to drizzle.
Example Sentences:
(1) In general, optimal DAGAT activity in vitro was observed when long-chain unsaturated acyl-CoAs and diacylglycerols (DAGs) containing long acyl chains were used as substrates for in vitro TAG synthesis (although 1,2-didecanoin was also very effective).
(2) Incubation of microsomes with CDP-DAG of different fatty acid composition results in quantitative and qualitative differences in lysoPI formation.
(3) We now report that two synthetic diacylglycerols (DAG) replicate the stimulatory and inhibitory effects of TPA on frog skin.
(4) The distribution of PKC returned to control values by 24 h. High glucose did not stimulate phosphoinositide hydrolysis, as evidenced by the absence of an increase in the water-soluble inositol phosphates, indicating that DAG was not generated through the action of a phosphoinositide-specific phospholipase C. Cells treated with the cell-permeable DAG analogue 1-oleoyl-2-acetyl glycerol to activate PKC displayed approximately two-fold increases of fibronectin, laminin, and type IV collagen mRNA levels after normalization against actin.
(5) We observed a 30-45% increase in DAG in rat gastrocnemius and diaphragm muscles, 5-15 min after intramuscular or intravenous injections of 1-3 U of insulin per rat, doses which would be expected to activate insulin receptors more fully.
(6) Concomitantly, an increase of inositol phosphates and diacylglycerol (DAG) production was observed.
(7) The accumulation of [14C]C20:4-DAG (lower in ET than in saline-infused rats) was paralleled by a decrease in phosphatidylinositol (PI) labelling, whereas phosphatidic acid showed a transient increase by 5 min in saline- but not in ET-infused rats.
(8) To determine the role of the DAG produced upon bombesin stimulation, we examined the effects of another activator of protein kinase C, the phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA).
(9) It is concluded that carbachol increases [Ca2+]i by facilitating Ca2+ entry through L-type Ca2+ channels via a 1,2-diacylglycerol (DAG)-protein kinase C (PKC)-dependent pathway while quisqualate mobilizes Ca2+ from inositol 1,4,5-trisphosphate (IP3)-sensitive stores.
(10) In order to characterize the properties of the glyceroglycolipid membranes, ESR spectroscopic studies were carried out with an acyl spin-labeled galactosyl ceramide (SL-GC) or a headgroup spin-labeled phospholipid (SL-6-DPPA) in 1,2-dipalmitoyl[beta-cellobiosyl-(1'---3)]glycerol (Cel-DAG) liposomal membranes.
(11) The E. coli dgkA locus which contains the coding sequences for DAG kinase was subcloned into an eukaryotic expression vector, pMT2.
(12) The mean residence time for pharmacologically active molecules in the body was six times shorter for DAG (1.9 hr) than for DBD (11.4 hr).
(13) These data suggest that PKC is a mediator in the generation of DAG.
(14) These results suggest that DAG accumulation is involved in the potentiating effect of A23187 on CCh-stimulated amylase secretion.
(15) It is concluded that insulin-dependent PDH activation, PIG hydrolysis, and IG and DAG generation are mediated by the wild-type but not by the mutated insulin receptor of Val996.
(16) Since most alloantibodies detected only by 2SP-IAT or LISS-DAG were of doubtful clinical significance, and these techniques produced a high number of unwanted positive reactivities, we conclude that 2SP-IAT and LISS-DAG are not appropriate for the pretransfusion screening for unexpected antibodies.
(17) 261, 8597-8600), lipase from Rhizopus arrhizus selectively degraded the 1-acyl-containing species (DAG), but the ether lipid (EAG) was resistant and was identified and quantified after thin layer chromatography separation.
(18) 1-Oleoyl-2-acetylglycerol, a synthetic DAG analog, stimulated endothelial cell DNA synthesis in a concentration-dependent manner.
(19) Whereas DPG and DS are stable at physiological pH, DAG is unstable, undergoing hydrolysis (regeneration of DF) and rearrangement (intramolecular acyl migration to the 2-, 3- and 4-O-acyl-positional isomers).
(20) Addition of PRL to hepatocyte cultures significantly increased [3H]-glycerol incorporation into DAG within 5 minutes which was followed by a loss of cytosolic PKC activity by 10 minutes.
Fag
Definition:
(n.) A knot or coarse part in cloth.
(v. i.) To become weary; to tire.
(v. i.) To labor to wearness; to work hard; to drudge.
(v. i.) To act as a fag, or perform menial services or drudgery, for another, as in some English schools.
(v. t.) To tire by labor; to exhaust; as, he was almost fagged out.
(v. t.) Anything that fatigues.
Example Sentences:
(1) Rebelling by dabbling in drink, fags, sex – the list goes on – is part of growing up.
(2) Here, we examine a group of six recessive mutations, the facets (fa, fa3, fag, fag-2, fafx and fasw), which affect eye and optic lobe morphology and have been previously shown to be associated with the insertion of transposable elements into an intronic region of Notch.
(3) There were 54 cases of somaticised anxiety (brain fag); 22 cases of depressive neurosis characterised by hypochondriasis, cognitive complaints, and culturally determined paranoid ideation; 23 cases of 'hysteria' in the form of dissociative states, pseudoseizures and fugues; and 39 cases of brief reactive psychosis which differed from the dissociative states more in duration and intensity than in form.
(4) The use of VW FAg levels in the diagnosis of vasculitic disorders has been proposed.
(5) It is the fact that the poor spend too much on fags and booze.
(6) In this paper an attempt has been made to tie the concept down more firmly by proposing a strict definition, examining the appropriateness of this definition in determining the CBS status of two new syndromes (anorexia nervosa and brain-fag) and analysing the usefulness or not of the basic CBS concept.
(7) In males, atrophic areas and the remaining choriocapillaris are clearly demonstrated in FAG and less well visible in ICG angiograms.
(8) At baseline, although the levels were not outside the laboratory range, the disease groups had raised VW FAg compared with the simultaneously tested controls.
(9) For those who like verisimilitude in their faux fags there are disposables – the hefty but effective Ten Motives or the petite, feminine NJOY – and rechargeable kits complete with USB chargers and cartridges from the likes of E-Lites, Halo and Skycig.
(10) Venostatic stress increased VW FAg activity in all disease groups, control levels also increased and differences between controls and disease groups diminished in significance.
(11) Brown's fear has been that he might inherit the fag end of a tired government.
(12) In other words, the noise surrounding this debate, not to mention the TV duel, will only partly be about whether Britain should be in Europe or not: the rest of it, one would imagine, will centre on the issue of immigration, both in terms of its links with the EU, and as a public concern that informs just about every other area of policy – and, implicitly or otherwise, the sense a lot of people have that we are governed by a homogeneous, well-heeled, cosseted bunch of politicians, and among the only people who offer any kind of alternative is Farage, complete with his pint and fag.
(13) At fluorescein angiography (FAG) at a mean of 8 months post-operatively, 9 showed leaking from the iridal vessels, and 3 were normal: Three cases were excluded because of factors affecting the iris FAG.
(14) He cycles down to the docks, puffs a fag and contemplates the water.
(15) In 1995, when Williams walked out on his boyband, he bounded into Liam's rock'n'roll life with ease – because although he had once writhed around in jelly , he also had a rebellious side with a penchant for Adidas jackets, booze, birds and fags.
(16) A lovely woman meets us, gives us fags in the cab and says she'll happily answer to the name of Dave too.
(17) ITV chief executive Charles Allen accused the corporation of "back of a fag packet" calculations after it requested an inflation-busting settlement that would result in the current £131.50 fee increase to more than £180 by 2014.
(18) "Obviously all the other cunts will have the same idea, and the motorways will be rammed," Dad continued, fag wedged in mouth, "so we'll be taking the back roads.
(19) In M-SHRSPs with age of 8 weeks, systolic blood pressure was 220mmHg or more and retinal arterioles showed generalised narrowing but no dye leakage was recognized by fluorescein angiography (FAG).
(20) The gently warm vapour ingeniously replicates the reflective pause of a real fag, the same quiet little buzz.