(v. t.) To cut into jags or points; to slash; as, to dag a garment.
(v. i.) To be misty; to drizzle.
Example Sentences:
(1) In general, optimal DAGAT activity in vitro was observed when long-chain unsaturated acyl-CoAs and diacylglycerols (DAGs) containing long acyl chains were used as substrates for in vitro TAG synthesis (although 1,2-didecanoin was also very effective).
(2) Incubation of microsomes with CDP-DAG of different fatty acid composition results in quantitative and qualitative differences in lysoPI formation.
(3) We now report that two synthetic diacylglycerols (DAG) replicate the stimulatory and inhibitory effects of TPA on frog skin.
(4) The distribution of PKC returned to control values by 24 h. High glucose did not stimulate phosphoinositide hydrolysis, as evidenced by the absence of an increase in the water-soluble inositol phosphates, indicating that DAG was not generated through the action of a phosphoinositide-specific phospholipase C. Cells treated with the cell-permeable DAG analogue 1-oleoyl-2-acetyl glycerol to activate PKC displayed approximately two-fold increases of fibronectin, laminin, and type IV collagen mRNA levels after normalization against actin.
(5) We observed a 30-45% increase in DAG in rat gastrocnemius and diaphragm muscles, 5-15 min after intramuscular or intravenous injections of 1-3 U of insulin per rat, doses which would be expected to activate insulin receptors more fully.
(6) Concomitantly, an increase of inositol phosphates and diacylglycerol (DAG) production was observed.
(7) The accumulation of [14C]C20:4-DAG (lower in ET than in saline-infused rats) was paralleled by a decrease in phosphatidylinositol (PI) labelling, whereas phosphatidic acid showed a transient increase by 5 min in saline- but not in ET-infused rats.
(8) To determine the role of the DAG produced upon bombesin stimulation, we examined the effects of another activator of protein kinase C, the phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA).
(9) It is concluded that carbachol increases [Ca2+]i by facilitating Ca2+ entry through L-type Ca2+ channels via a 1,2-diacylglycerol (DAG)-protein kinase C (PKC)-dependent pathway while quisqualate mobilizes Ca2+ from inositol 1,4,5-trisphosphate (IP3)-sensitive stores.
(10) In order to characterize the properties of the glyceroglycolipid membranes, ESR spectroscopic studies were carried out with an acyl spin-labeled galactosyl ceramide (SL-GC) or a headgroup spin-labeled phospholipid (SL-6-DPPA) in 1,2-dipalmitoyl[beta-cellobiosyl-(1'---3)]glycerol (Cel-DAG) liposomal membranes.
(11) The E. coli dgkA locus which contains the coding sequences for DAG kinase was subcloned into an eukaryotic expression vector, pMT2.
(12) The mean residence time for pharmacologically active molecules in the body was six times shorter for DAG (1.9 hr) than for DBD (11.4 hr).
(13) These data suggest that PKC is a mediator in the generation of DAG.
(14) These results suggest that DAG accumulation is involved in the potentiating effect of A23187 on CCh-stimulated amylase secretion.
(15) It is concluded that insulin-dependent PDH activation, PIG hydrolysis, and IG and DAG generation are mediated by the wild-type but not by the mutated insulin receptor of Val996.
(16) Since most alloantibodies detected only by 2SP-IAT or LISS-DAG were of doubtful clinical significance, and these techniques produced a high number of unwanted positive reactivities, we conclude that 2SP-IAT and LISS-DAG are not appropriate for the pretransfusion screening for unexpected antibodies.
(17) 261, 8597-8600), lipase from Rhizopus arrhizus selectively degraded the 1-acyl-containing species (DAG), but the ether lipid (EAG) was resistant and was identified and quantified after thin layer chromatography separation.
(18) 1-Oleoyl-2-acetylglycerol, a synthetic DAG analog, stimulated endothelial cell DNA synthesis in a concentration-dependent manner.
(19) Whereas DPG and DS are stable at physiological pH, DAG is unstable, undergoing hydrolysis (regeneration of DF) and rearrangement (intramolecular acyl migration to the 2-, 3- and 4-O-acyl-positional isomers).
(20) Addition of PRL to hepatocyte cultures significantly increased [3H]-glycerol incorporation into DAG within 5 minutes which was followed by a loss of cytosolic PKC activity by 10 minutes.
Loser
Definition:
(n.) One who loses.
Example Sentences:
(1) A good chunk of the Trump base consists of people who consider themselves to be losers from four decades of political and economic orthodoxy.
(2) Instead he stood there as the only prime minister in the room – and the one great loser was the man who wasn’t there.
(3) These differences in hormonal responses to the fight are attributed to the more aggressive behavior displayed by the victorious opponents (winners) over their defeated competitors (losers).
(4) The victims of violence in 2007-08 are the losers."
(5) Our economic system has always required winners and losers.
(6) While the loser of an election is sometimes viewed as the leader of the out-of-power party, Clinton, at 69, is not positioned to make a third run for the White House and no longer sits atop a money-filled political organization.
(7) Longitudinal analyses including (a) comparisons of risk factor changes in subjects grouped as fitness "losers", "stable", "small gain", and "large gain", and (b) multiple regression analyses of relationships between fitness change and risk factor changes showed that fitness change was largely unrelated to risk factor changes.
(8) While this one will not go down as a comparable game-changer, it will at least change the growing perception of Romney as a loser, even if only temporarily.
(9) Toronto Cheapest for salmon Pricey for almost everything else Canada's biggest city came out the surprise loser in our survey, with our basket of goods costing 40% more in Toronto than in Berlin.
(10) The big symbolic loser is the Times, down 14.2% year on year: it has dropped back below 500,000, and is heading for the sort of sale it used to command before its long, expensive price war with the Telegraph.
(11) The biggest loser could be the state-owned oil company Rosneft, which bought Yukos assets in auctions when the latter's stock was almost worthless.
(12) Data indicated that the winners more nearly approximated their predicted weight than did the losers.
(13) Early on Sunday morning, Malcolm Turnbull looked out to the Australian electorate and expressed his own profound alienation from the lived experiences of the losers of globalisation – the people who had flocked to Nick Xenophon and Pauline Hanson and to Labor on the basis that the ALP had climbed down partially from the neoliberal pedestal constructed by Bob Hawke and Paul Keating.
(14) Many commentators considered the suggestion merely foolish, but computer hackers issued death threats against her and her children, which she promptly posted on Twitter, along with the defiant message: "Get stuffed, losers.
(15) Only last month the Financial Conduct Authority issued a report in which it said millions of older people were getting a poor deal from Britain's multibillion-pound annuity market, with the biggest losers those with the least money put aside for their retirement.
(16) We will take care of each individual customer who is affected.” VW scandal: the winners and losers, from carmakers to car owners Read more VW said overall sales were down 1.5% in Europe in October, but rose 6.8% in North America and were up 1.6% in China.
(17) One of the biggest losers are the estimated 12-20 million illegal immigrants living in the US, most of whom play an integral role in the economy, doing menial jobs that citizens do not want.
(18) The balance studies included not only urine and fecal loss but also skin, menstrual and hair losers.
(19) The most recent polling shows that backing the full replacement of Trident is not necessarily a vote winner, nor is opposing it necessarily a vote loser.
(20) The greatest loser is France, outcompeted by Germany within the eurozone, with poor growth prospects, large deficits, and its welfare system under strain.