(a.) Destitute, or partially destitute, of light; not receiving, reflecting, or radiating light; wholly or partially black, or of some deep shade of color; not light-colored; as, a dark room; a dark day; dark cloth; dark paint; a dark complexion.
(a.) Not clear to the understanding; not easily seen through; obscure; mysterious; hidden.
(a.) Destitute of knowledge and culture; in moral or intellectual darkness; unrefined; ignorant.
(a.) Evincing black or foul traits of character; vile; wicked; atrocious; as, a dark villain; a dark deed.
(n.) Absence of light; darkness; obscurity; a place where there is little or no light.
(n.) The condition of ignorance; gloom; secrecy.
(n.) A dark shade or dark passage in a painting, engraving, or the like; as, the light and darks are well contrasted.
(v. t.) To darken to obscure.
Example Sentences:
(1) And that, as much as the “on water, operational” considerations, is why we are being kept in the dark.
(2) The first group was reared in complete darkness while the second one was subjected to permanent noise.
(3) In the dark the 6-azidoflavoproteins are quite stable, except for L-lactate oxidase, where spontaneous conversion to the 6-amino-FMN enzyme occurs slowly at pH 7.
(4) Most notably, retroperitoneal lymph nodes in rabbits remained dark blue up to 28 days after hindlimb endolymphatic instillation of liposomal patent blue.
(5) In the dark cortical zone of the nodes (III group) there occur tissue basophils (mast cells), that, together with increasing number of acidophilic granulocytes and appearance of neutrophilic cells, demonstrates that there is an inflammatory reaction in the organ studied as a response to the lymphocytic suspension injected.
(6) Urinalysis revealed a low pH, increased ketones and bilirubin excretion, dark yellowish change in color, the appearance of "leaflet-shaped" crystals and increased red blood cells and epithelial cells in the urinary sediment, increased water intake, decreased specific gravity and decreased sodium, potassium and chloride in the urine.
(7) We were searching for spontaneous and positional nystagmus in 5 positions with open eyes in darkness and with closed eyes.
(8) Previous FTIR measurements have identified several tyrosine residues that change their absorption characteristics between light-adapted BR and dark-adapted BR, or between intermediates K and M [Dollinger, G., Eisenstein, L., Lin, S.-L., Nakanishi, K., Odashima, K., & Termini, J.
(9) Steady state levels of chloroplast mRNA encoding the core PSII polypeptides remain nearly constant in the light or the dark and are not affected by the developmental stage of the plastid.
(10) The second triplet, which was stable in the dark at 4.2 K following illumination, was assigned to the radical pair Donor+I-.
(11) The results indicate that CRALBP X 11-cis-retinol is sufficiently stereoselective in its binding properties to warrant consideration as a component of the mechanism for the generation of 11-cis-retinaldehyde in the dark.
(12) Although the Ca2+-independent mechanism accounts for about two thirds of the total acetylcholine release in the dark, the amount of acetylcholine released in this way is small compared with the release of acetylcholine triggered by stimulation of the retina with light.
(13) The extracellular concentration of GABA is probably high in prolonged darkness, and it is low after prolonged light exposure.
(14) In lettuce, the presence of 2,4-D in the light lowered the concentration of total Hg (or MeHg) required to reduce growth by 50%, about 13 times relative to that in the dark (i.e., it sensitized the cells).
(15) This suggests that many retinal ganglion cells continue to discharge in total darkness for long periods.
(16) In darkness, raising the concentration of K in the fluid of perfusion gives an increase of the efflux of (86)Rb and increasing the extracellular concentration of Ca yields a retention.
(17) Upon illumination, a dark-adapted photosynthetic sample shows time-dependent changes in chlorophyll (Chl) a fluorescence yield, known as the Kautsky phenomenon or the OIDPS transient.
(18) One elderly woman was left alone in the dark for hours unable to find food or drink.
(19) These observations indicated a novel mechanism that in the absence of light-dark schedule, mothers taught the circadian rhythm to the pups as they raised them.
(20) It was observed that the circadian rhythm was disrupted by injections of lithium at the beginning of the light as well as the dark phase of the LD cycle.
Mark
Definition:
(n.) A license of reprisals. See Marque.
(n.) An old weight and coin. See Marc.
(n.) The unit of monetary account of the German Empire, equal to 23.8 cents of United States money; the equivalent of one hundred pfennigs. Also, a silver coin of this value.
(n.) A visible sign or impression made or left upon anything; esp., a line, point, stamp, figure, or the like, drawn or impressed, so as to attract the attention and convey some information or intimation; a token; a trace.
(n.) A character or device put on an article of merchandise by the maker to show by whom it was made; a trade-mark.
(n.) A character (usually a cross) made as a substitute for a signature by one who can not write.
(n.) A fixed object serving for guidance, as of a ship, a traveler, a surveyor, etc.; as, a seamark, a landmark.
(n.) A trace, dot, line, imprint, or discoloration, although not regarded as a token or sign; a scratch, scar, stain, etc.; as, this pencil makes a fine mark.
(n.) An evidence of presence, agency, or influence; a significative token; a symptom; a trace; specifically, a permanent impression of one's activity or character.
(n.) That toward which a missile is directed; a thing aimed at; what one seeks to hit or reach.
(n.) Attention, regard, or respect.
(n.) Limit or standard of action or fact; as, to be within the mark; to come up to the mark.
(n.) Badge or sign of honor, rank, or official station.
(n.) Preeminence; high position; as, particians of mark; a fellow of no mark.
(n.) A characteristic or essential attribute; a differential.
(n.) A number or other character used in registring; as, examination marks; a mark for tardiness.
(n.) Image; likeness; hence, those formed in one's image; children; descendants.
(n.) One of the bits of leather or colored bunting which are placed upon a sounding line at intervals of from two to five fathoms. The unmarked fathoms are called "deeps."
(v. t.) To put a mark upon; to affix a significant mark to; to make recognizable by a mark; as, to mark a box or bale of merchandise; to mark clothing.
(v. t.) To be a mark upon; to designate; to indicate; -- used literally and figuratively; as, this monument marks the spot where Wolfe died; his courage and energy marked him for a leader.
(v. t.) To leave a trace, scratch, scar, or other mark, upon, or any evidence of action; as, a pencil marks paper; his hobnails marked the floor.
(v. t.) To keep account of; to enumerate and register; as, to mark the points in a game of billiards or cards.
(v. t.) To notice or observe; to give attention to; to take note of; to remark; to heed; to regard.
(v. i.) To take particular notice; to observe critically; to note; to remark.
Example Sentences:
(1) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
(2) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(3) Following in vitro C activation in NHS by delta IgG, the 40 KD C4d component increased markedly.
(4) However, when cross-linked to anti-CD4 or anti-CD8 antibodies a markedly enhanced proliferation of the corresponding subpopulation is observed.
(5) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(6) Increased dietary protein intake led to increased MDA per nephron, increased urinary excretion of MDA, and increased MDA per milligram protein in subtotally nephrectomized animals, and markedly increased the glutathione redox ratio.
(7) Cyclic AMP stimulated phosphorylation by [gamma-32P]ATP of two proteins of apparent Mr = 20,000 and 7,000 that were concentrated in sarcoplasmic reticulum, but the stimulation was markedly dependent on the presence of added soluble cyclic AMP-dependent protein kinase.
(8) Surprisingly, the clonal elimination of V beta 6+ cells is preceded by marked expansion of these cells.
(9) Muscle weakness and atrophy were most marked in the distal parts of the legs, especially in the gastrocnemius and soleus muscles, and then spread to the thighs and gluteal muscles.
(10) of PLA2 caused marked degranulation of mast cells in the rat mesentery which was facilitated by addition of calcium ion (10 mM) but antagonized by pretreating with three antiinflammatory agents.
(11) report the complications registered, in particular: lead's displacing 6.2%, run away 0.7%, marked hyperthermya 0.0%, haemorrage 0.4%, wound dehiscence 0.3%, asectic necrosis by decubitus 5%, septic necrosis 0.3%, perforation of the heart 0.2%, pulmonary embolism 0.1%.
(12) Marked enhancement of IFN-gamma production by T cells was seen in the presence of as little as 0.3% thymic DC.
(13) This effect was more marked in breast cancer patients which may explain our earlier finding that women with upper body fat localization are at increased risk for developing breast cancer.
(14) Completeness of isolation of the coronary and systemic circulations was shown by the marked difference in appearance times between the reflex hypotensive responses from catecholamine injections into the isolated coronary circulation and the direct hypertensive response from a similar injection when the circulations were connected as well as by the marked difference between the pressure pulses recorded simultaneously on both sides of the aortic balloon separating the two circulations.4.
(15) A marked overlap of input from the two eyes is an unusual feature for a diprotodont marsupial and has previously been seen only in the feathertail glider.
(16) The erythrocyte sedimentation rate is almost always markedly elevated.
(18) Sixteen patients (27%) manifested anomalies of the urinary tract: 12 had markedly altered kidneys, 8 of which were unilateral and ipsilateral to the diaphragmatic defect.
(19) Her muscle weakness and hyperCKemia markedly improved by corticosteroid therapy, suggesting that the diagnosis was compatible with polymyositis (PM).
(20) The introduction of intravenous, high-dose thrombolytic therapy during a brief period has markedly reduced mortality of patients with acute myocardial infarction.