(a.) Destitute, or partially destitute, of light; not receiving, reflecting, or radiating light; wholly or partially black, or of some deep shade of color; not light-colored; as, a dark room; a dark day; dark cloth; dark paint; a dark complexion.
(a.) Not clear to the understanding; not easily seen through; obscure; mysterious; hidden.
(a.) Destitute of knowledge and culture; in moral or intellectual darkness; unrefined; ignorant.
(a.) Evincing black or foul traits of character; vile; wicked; atrocious; as, a dark villain; a dark deed.
(n.) Absence of light; darkness; obscurity; a place where there is little or no light.
(n.) The condition of ignorance; gloom; secrecy.
(n.) A dark shade or dark passage in a painting, engraving, or the like; as, the light and darks are well contrasted.
(v. t.) To darken to obscure.
Example Sentences:
(1) And that, as much as the “on water, operational” considerations, is why we are being kept in the dark.
(2) The first group was reared in complete darkness while the second one was subjected to permanent noise.
(3) In the dark the 6-azidoflavoproteins are quite stable, except for L-lactate oxidase, where spontaneous conversion to the 6-amino-FMN enzyme occurs slowly at pH 7.
(4) Most notably, retroperitoneal lymph nodes in rabbits remained dark blue up to 28 days after hindlimb endolymphatic instillation of liposomal patent blue.
(5) In the dark cortical zone of the nodes (III group) there occur tissue basophils (mast cells), that, together with increasing number of acidophilic granulocytes and appearance of neutrophilic cells, demonstrates that there is an inflammatory reaction in the organ studied as a response to the lymphocytic suspension injected.
(6) Urinalysis revealed a low pH, increased ketones and bilirubin excretion, dark yellowish change in color, the appearance of "leaflet-shaped" crystals and increased red blood cells and epithelial cells in the urinary sediment, increased water intake, decreased specific gravity and decreased sodium, potassium and chloride in the urine.
(7) We were searching for spontaneous and positional nystagmus in 5 positions with open eyes in darkness and with closed eyes.
(8) Previous FTIR measurements have identified several tyrosine residues that change their absorption characteristics between light-adapted BR and dark-adapted BR, or between intermediates K and M [Dollinger, G., Eisenstein, L., Lin, S.-L., Nakanishi, K., Odashima, K., & Termini, J.
(9) Steady state levels of chloroplast mRNA encoding the core PSII polypeptides remain nearly constant in the light or the dark and are not affected by the developmental stage of the plastid.
(10) The second triplet, which was stable in the dark at 4.2 K following illumination, was assigned to the radical pair Donor+I-.
(11) The results indicate that CRALBP X 11-cis-retinol is sufficiently stereoselective in its binding properties to warrant consideration as a component of the mechanism for the generation of 11-cis-retinaldehyde in the dark.
(12) Although the Ca2+-independent mechanism accounts for about two thirds of the total acetylcholine release in the dark, the amount of acetylcholine released in this way is small compared with the release of acetylcholine triggered by stimulation of the retina with light.
(13) The extracellular concentration of GABA is probably high in prolonged darkness, and it is low after prolonged light exposure.
(14) In lettuce, the presence of 2,4-D in the light lowered the concentration of total Hg (or MeHg) required to reduce growth by 50%, about 13 times relative to that in the dark (i.e., it sensitized the cells).
(15) This suggests that many retinal ganglion cells continue to discharge in total darkness for long periods.
(16) In darkness, raising the concentration of K in the fluid of perfusion gives an increase of the efflux of (86)Rb and increasing the extracellular concentration of Ca yields a retention.
(17) Upon illumination, a dark-adapted photosynthetic sample shows time-dependent changes in chlorophyll (Chl) a fluorescence yield, known as the Kautsky phenomenon or the OIDPS transient.
(18) One elderly woman was left alone in the dark for hours unable to find food or drink.
(19) These observations indicated a novel mechanism that in the absence of light-dark schedule, mothers taught the circadian rhythm to the pups as they raised them.
(20) It was observed that the circadian rhythm was disrupted by injections of lithium at the beginning of the light as well as the dark phase of the LD cycle.
Pessimistic
Definition:
(a.) Of or pertaining to pessimism; characterized by pessimism; gloomy; foreboding.
Example Sentences:
(1) A rather pessimistic wind is blowing over cancer chemotherapy, while a not very objective enthusiasm for second generation immunotherapy is raising its head.
(2) We challenge this pessimistic approach, and describe here our experience with seven patients with solid tumors, in whom pericardial effusion was diagnosed; one of them is described in detail.
(3) Verbally abused children were more angry and more pessimistic about their future.
(4) Has recently sounded pessimistic about the prospects for a full post-Copenhagen treaty: "You should not have too many expectations."
(5) Two groups, one institutionalized and the other noninstitutionalized but without formal activities, were described as being disengaged: e.g., withdrawn socially, self-absorbed, as well as powerless, pessimistic, and depressed.
(6) It is concluded that the heretofore pessimistic outlook regarding complete quadriplegia is unwarranted and that a more aggressive approach may result in a better functional outcome.
(7) "What our study has shown is that this applies similarly to dogs – that a 'glass half full' dog is less likely to be anxious when left alone than one with a more 'pessimistic' nature."
(8) "It's like watching a bullfight," says one Conservative backbench pessimist.
(9) The agency hopes it can later extend the work to urban rivers outside London, but is pessimistic that parts of the Fleet might one day be released to public view.
(10) It is a totally unrealistic, pessimistic vision about what this country can achieve."
(11) Rehabilitation of patients with chronic respiratory disease has tended to be neglected in the past, partly because of a generally pessimistic view of their prospects.
(12) Another important factor is the lack of motivation shown by attending physicians to detect less obvious cases of alcohol dependence as they feel pessimistic about dealing with this condition.
(13) Predictions based on very early assessment are, therefore, often unduly pessimistic.
(14) If we’re being pessimistic about it, the whole idea of the euro has been weakened and maybe we’ll look back and see this as the beginning of the end of that ideal.” She reflected a pessimistic feeling among Germans, whether financial experts or ordinary folk on the street, that the whole of Europe had taken a battering over the negotiations, one from which it would take time to recover; and the strong belief that the very same politicians would once again find themselves in a huddle over the same issue a few months down the line.
(15) A substantial number of people who start small businesses have no qualifications beyond secondary school, he says, and, worse, may have no technical or business management training Peter Strong, of the Small Business Association , is less pessimistic.
(16) The estimated overall risk difference remained negative even when all patients in the sclerotherapy group with an unknown survival status were pessimistically considered dead at the end of the follow-up period.
(17) In the pessimistic case, UK income falls by 3.1%, or £50bn a year.” More business leaders lined up on Thursday to voice their concerns that the UK economy will be a significant casualty of a decision to leave the EU, including Sir Martin Sorrell, chief executive of the advertising firm WPP.
(18) It is a measure of how pessimistic the MPC has become that even a one percentage point lowering in the assumed policy rate profile was deemed insufficient to offset the bad news on demand.
(19) The only thing maintaining the flow of migrants is that nobody reads the Daily Mail until they arrive, and only then do they realise how coarse and brutal our politics have become, how pessimistic.
(20) Women and more pessimistic parents were more distressed.