(a.) Unnatural or distorted in form; having a deformity; misshapen; disfigured; as, a deformed person; a deformed head.
Example Sentences:
(1) Gross deformity, point tenderness and decrease in supination and pronation movements of the forearm were the best predictors of bony injury.
(2) Rigidly fixing the pubic symphysis stiffened the model and resulted in principal stress patterns that did not reflect trabecular density or orientations as well as those of the deformable pubic symphysis model.
(3) Cloacal exstrophy, centered on the maldevelopment of the primitive streak mesoderm and cloacal membrane, results in bladder and intestinal exstrophy, omphalocele, gender confusion, and hindgut deformity.
(4) In a family with hereditary elliptocytosis and an abnormality in spectrin self-association, the membranes had decreased deformability and stability.
(5) The most important causal factor, well illustrated by pressure studies, was the presence of a dynamic or static deformity leading to local areas of peak pressure on insensitive skin.
(6) Predominantly observed defects included neural crest cells in ectopic locations, both within and external to the neural tube, and mildly deformed neural tubes containing some dissociating cells.
(7) Emergency CT showed evidence of pericardial effusion suggesting hemopericardium, enlargement of the ascending aorta and a peripheral semilunar filling defect which caused a slight deformation of the true channel.
(8) Changes in the determinants of blood viscosity (packed cell volume, plasma viscosity, red cell aggregation, and red cell deformability) were studied on day 1 and day 5.
(9) A model for left ventricular diastolic mechanics is formulated that takes into account noneligible wall thickness, incompressibility, finite deformation, nonlinear elastic effects, and the known fiber architecture of the ventricular wall.
(10) As a consequence of deformation from spherical-to-cylindrical shape in the microvasculature, demands for increased surface membrane area leads to increases in surface membrane tension above critical levels for rupture, and the cancer cells are rapidly and lethally damaged.
(11) Within the restriction provided by surface area and volume, the intrinsic properties of the membrane and cytoplasm determine the deformability characteristics of the red cell.
(12) In 12 patients with lower macrognathia we have applied a technique allowing to prevent the postsurgical recidives of the jaw deformation.
(13) Filtration of red blood cells through agarose gels (Sephadex, Sepharose, and Superose) was used to assess red cell deformability and simultaneously obtain fractions of red cells with different properties.
(14) Such deformities may be the only future indication for the use of this operation as these knees do not do well when treated by tibial osteotomy.
(15) Richard now is presented, albeit somewhat inconsistently, as evil in response to social ostracism because of his ugly deformities.
(16) Calcium-dependent ATPase, adenylate cyclase and phosphorylation of erythrocyte membrane proteins have been found abnormal in various conditions: hereditary spherocytosis, sickle-cell anemia, progressive muscular dystrophies, all of these disorders being associated with a decreased deformability of the erythrocyte.
(17) Thus many athletes sustain dental-related injuries resulting in deformity and discomfort which may persist throughout their lives.
(18) Type II had the anastomosis too high on the gastric pouch, type III was due to an obstructing marginal ulcer, and type IV had a pouchlike deformity develop in the upper jejunum at the anastomosis that gradually compressed the outflow tract.
(19) This procedure was done in 4 patients and corrected the deformity efficiently, allowing for satisfactory sexual function.
(20) Angiography was performed on 74 hands of 70 patients in this series, and attempts were made to correlate these with the types of the deformities.
Oaf
Definition:
(n.) Originally, an elf's child; a changeling left by fairies or goblins; hence, a deformed or foolish child; a simpleton; an idiot.
Example Sentences:
(1) Big OAF was converted to little OAF by equilibration in 1 M NaCl or 2 M urea.
(2) Outside, there’s no sign of life except one bearded oaf on a chopper and a kid at the back door, holding a picture of Hot Fuss-era Brandon Flowers , praying for a brief encounter.
(3) The effect of interleukin-1 beta, the major component of osteoclast-activating factor (OAF), on bone formation by fetal rat osteoblast-rich cells was investigated.
(4) Recent studies show that osteoclast activating factor (OAF) is homologous to IL-1B.
(5) The resorption response to OAF also resembles that of PTH in having a steep dose response curve and being only transiently inhibited by calcitonin and partially inhibited by increasing medium phosphate concentration.
(6) Spleen cells treated with mitogens produce a potent bone-resorbing factor called osteoclast-activating factor (OAF).
(7) In contrast, supernatant fluids from concanavalin A (Con-A)-activated murine spleen cell cultures (murine osteoclast-activating factor; OAF) consistently and significantly induced a 3- to 5-fold stimulation of bone resorption in this system.
(8) OAF production is probably related to the nature of hydrocarbons in the air.
(9) Calcium release was significantly increased for all agents between 12 and 24 h. It is concluded that bone resorption by 1,25(OH)2D3, OAF, and PGE2 is mediated primarily by increased activity of existing osteoclasts similar to PTH activation.
(10) The presence of bactericidal compounds (open air factor = OAF) could be demonstrated on several days and quantitated in relative units of OAF concentration.
(11) The current studies were designed to produce monoclonal antibodies against OAF for use in the subsequent design of immunoassays for OAF in clinical samples.
(12) In this study we examined the relationship between the lymphocyte and monocyte in OAF production.
(13) The lymphokine osteoclast-activating factor (OAF) was purified to homogeneity.
(14) These results indicate that prostaglandin synthesis is necessary for OAF production.
(15) Are there really "nine sleeps 'til new Who" you gurgling oaf?
(16) Bones from mi mice showed a generalized resorption defect with decreased spontaneous or control resorption and failure to respond to parathyroid hormone (PTH), prostaglandin E2, 1,25 dihydroxy vitamin D3, vitamin A, or osteoclast activating factor (OAF) from human peripheral leukocytes or mouse spleen cells.
(17) OAF release was stimulated by pokeweed mitogen and concanavalin A as well as by phytohemagglutinin.
(18) When PGE1 and PGE2 (0.1 microM) were added exogenously to the enriched lymphocyte population, OAF release occurred after stimulation with PHA.
(19) We have further characterized osteoclast activating factor (OAF) using a bioassay for bone resorption which utilizes the release of previously incorporated (45)Ca from fetal rat long bones in organ culture.
(20) The demonstration of increased osteoclast activating factor (OAF) derived from the cultured myeloma cells from each case suggests that the secretion of OAF and immunoglobulin are unrelated.