(a.) Having become worse than one's kind, or one's former state; having declined in worth; having lost in goodness; deteriorated; degraded; unworthy; base; low.
(v. i.) To be or grow worse than one's kind, or than one was originally; hence, to be inferior; to grow poorer, meaner, or more vicious; to decline in good qualities; to deteriorate.
(v. i.) To fall off from the normal quality or the healthy structure of its kind; to become of a lower type.
Example Sentences:
(1) Thus, our results indicate that calbindin-D28k is a useful marker for the projection system from the matrix compartment and that its expression is modified in patients with progressive supranuclear palsy and striatal degeneration.
(2) Achilles tendon overuse injuries exist as a spectrum of diseases ranging from inflammation of the paratendinous tissue (paratenonitis), to structural degeneration of the tendon (tendinosis), and finally tendon rupture.
(3) Electroretinographic (ERG), morphometric and biochemical studies on retinas from monkeys or rats reveal that moderate level developmental lead (Pb) exposure produces long-term selective rod deficits and degeneration.
(4) of rats resulted in cell death and terminal degeneration in entorhinal, insular, and posterior cingulate cortices, and in the CA1, CA3 and dentate gyrus sectors of hippocampus.
(5) Certain underlying factors in several types of retinal degeneration are first discussed, followed by characteristics of diabetic maculopathy and of other types of macular degeneration including that due to aging.
(6) Hyperopia was more common in younger persons, but senile cataract, macular degeneration and palpebral dermatochalasis or blepharochalasis were more common in older persons.
(7) Since only a few of these medium sized terminals in any one cluster degenerate after tectal lesions, and none degenerate after cortical lesions, it is suggested that the morphological arrangement of these clusters may permit the convergence of axons from several sources, some of which are unidentified, onto the same dendritic segment.
(8) Age-related macular degeneration (ARMD) is one of the leading causes of severe visual loss in the United States.
(9) Deafferentation of certain brain regions in adult animals results in (1) the disappearance of degenerating axon terminals and (2) in the temporary persistence of vacant postsynaptic sites.
(10) The eye of a patient with age-related macular degeneration was treated with krypton laser photocoagulation and later studied histopathologically.
(11) At hypothyroid patients there is an ADP excess which is degenerated to xanthine, the substrate of xanthine oxidase resulting in toxic anion superoxide and UA.
(12) After 7 days, various stages of sensory hair degeneration could be observed.
(13) I think you're probably right that the accent does degenerate along with Richard.
(14) Optical light, transmission, and scanning electron microscopy were used in investigations of epithelia in the glandular region of the milk cistern and greater lactiferous ducts and yielded the following findings, four and six hours from infection: degeneration and necrosis of epithelial cells, intraepithelial foreign cell infiltration (neutrophilic granulocytes, lymphocytes, macrophages), intra-epithelial oedema and locally delimited epithelial loss.
(15) Meanwhile, in the US, Ellen DeGeneres , who is 56 and came out in the 90s, is still flying the lesbian flag on TV.
(16) Key findings include a progressive degeneration of these cholinergic neurons characterized by the formation of immunoreactively atypical NFT, the loss of intraneuronal lipofuscin, a lack of senile plaque and beta-amyloid deposition within the basal forebrain, and end-stage gliosis without residual extracellular NFT.
(17) Differential degeneration of the lateral microvessels may account for increases in collagen nodule growth and ultimate size.
(18) Ultrastructurally, the atrial myocardial cells in all three patients were hypertrophied, and two patients had evidence of focal cell degeneration; the atrium was markedly dilated, but atrial arrhythmias were not noted.
(19) Pathological consequences of these events include inflammatory neutrophil infiltration, damage to the collagen and mucosal basement membrane, increased capillary permeability, edema, cell degeneration and necrosis.
(20) These tangential fibers are in part the preterminal arborizations of geniculocortical axons, since some of them have been shown to degenerate after geniculate lesions.
Lose
Definition:
(v. t.) To part with unintentionally or unwillingly, as by accident, misfortune, negligence, penalty, forfeit, etc.; to be deprived of; as, to lose money from one's purse or pocket, or in business or gaming; to lose an arm or a leg by amputation; to lose men in battle.
(v. t.) To cease to have; to possess no longer; to suffer diminution of; as, to lose one's relish for anything; to lose one's health.
(v. t.) Not to employ; to employ ineffectually; to throw away; to waste; to squander; as, to lose a day; to lose the benefits of instruction.
(v. t.) To wander from; to miss, so as not to be able to and; to go astray from; as, to lose one's way.
(v. t.) To ruin; to destroy; as destroy; as, the ship was lost on the ledge.
(v. t.) To be deprived of the view of; to cease to see or know the whereabouts of; as, he lost his companion in the crowd.
(v. t.) To fail to obtain or enjoy; to fail to gain or win; hence, to fail to catch with the mind or senses; to miss; as, I lost a part of what he said.
(v. t.) To cause to part with; to deprive of.
(v. t.) To prevent from gaining or obtaining.
(v. i.) To suffer loss, disadvantage, or defeat; to be worse off, esp. as the result of any kind of contest.
Example Sentences:
(1) It is my desperate hope that we close out of town.” In the book, God publishes his own 'It Getteth Better' video and clarifies his original writings on homosexuality: I remember dictating these lines to Moses; and afterward looking up to find him staring at me in wide-eyed astonishment, and saying, "Thou do knowest that when the Israelites read this, they're going to lose their fucking shit, right?"
(2) In fact, you might read it as a signal … that the president might well lose on this,” she said.
(3) Shelter’s analysis of MoJ figures highlights high-risk hotspots across the country where families are particularly at risk of losing their homes, with households in Newham, east London, most exposed to the possibility of eviction or repossession, with one in every 36 homes threatened.
(4) The effects of brain injury can be catastrophic and long-term so the impact of more research would be vast, but affected numbers are too small so it loses out.
(5) Larvae from fresh water eggs, cultured in fresh water and 'normal' laboratory cultures reached 50% infectivity in 3-5 days, losing potential infectivity in 11-15 days post-hatching.
(6) He's called out for his lack of imagination in a stinging review by a leading food critic (Oliver Platt) and - after being introduced to Twitter by his tech-savvy son (Emjay Anthony) - accidentally starts a flame war that will lead to him losing his job.
(7) • young clownfish will lose their ability to "smell" the anemone species that they shelter in.
(8) c-WRT-7 cells were found to differentiate into macrophage-like cells and to lose their growth capacity both in vitro and in vivo after incubation with LPS.
(9) By using these larger catheters, the surgeon will not lose the option of using isosmotic preparations.
(10) Winning and losing were predicted to be more significant in determining cardiovascular responses for Type A's than for Type B's.
(11) "I have to say that I have been a Chelsea player since 2004 and I have never had six minutes in my favour when I was losing.
(12) He would still lose some of his original cash, but it would be less.
(13) Moreover, respondents indicating initially relatively high levels of emotional eating who reported a reduction in that level were found to lose significantly (p less than 0.01) more reported weight and to be significantly (p less than 0.05) more successful at approaching target weight over the period of the study than respondents who continued to report high levels of emotional eating.
(14) In addition, we have shown that long-lived, presumably non-senescent, strains do not arise by suppressor mutation, but lose senescence plasmid DNA by another mechanism.
(15) We find that the labelled cell has a myelinated axon, but that the axon loses its myelin within 50 microns of the soma and has not yet been traced further.
(16) Duraphat-treated samples submerged in water after the exposure lost only about 50% of the deposited fluoride, whereas samples treated with 2% NaF are known to lose all their fluoride under similar circumstances, a condition which may be related to the favorable clinical effect of Duraphat.
(17) In the midst of all the newspaper headlines and vigils you can sometimes lose sight of the man who was on death row.
(18) Last month Walsall council announced it would close 15 of its 16 libraries, and residents told the Guardian they stood to lose vital community spaces as well as reading resources.
(19) Rayburn, who was also told by his jobcentre he would lose his benefits if he did not work without pay, said he spent almost two months stacking and cleaning shelves and sometimes doing night shifts.
(20) A growing educated middle class is losing touch with apartheid history and seeking alternatives.