(v. t.) To reduce from a higher to a lower rank or degree; to lower in rank; to deprive of office or dignity; to strip of honors; as, to degrade a nobleman, or a general officer.
(v. t.) To reduce in estimation, character, or reputation; to lessen the value of; to lower the physical, moral, or intellectual character of; to debase; to bring shame or contempt upon; to disgrace; as, vice degrades a man.
(v. t.) To reduce in altitude or magnitude, as hills and mountains; to wear down.
(v. i.) To degenerate; to pass from a higher to a lower type of structure; as, a family of plants or animals degrades through this or that genus or group of genera.
Example Sentences:
(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.
Demean
Definition:
(v. t.) To manage; to conduct; to treat.
(v. t.) To conduct; to behave; to comport; -- followed by the reflexive pronoun.
(v. t.) To debase; to lower; to degrade; -- followed by the reflexive pronoun.
(v. t.) Management; treatment.
(v. t.) Behavior; conduct; bearing; demeanor.
(n.) Demesne.
(n.) Resources; means.
Example Sentences:
(1) And in November, the US sixth circuit court of appeals ruled against these decisions , leaving Johnson and Campion in the same demeaning and inconvenient legal status they have faced since getting together.
(2) 9.41pm BST Dodgers 0 - Cardinals 0, bottom of the 2nd The "demeaning euphemism for overweight" Matt Adams lines out to Adrian Gonzalez for the second out of the inning.
(3) "The culture of demeaning women in pop music is so ingrained as to become routine, from the way we are dealt with by management and labels, to the way we are presented to the public."
(4) Surprise backing There is one bright spot for José Mourinho , as Alex Ferguson appears to debunk one of the more demeaning vignettes of recent years.
(5) It would be unfair – daft, even, and demeaning to the winner – to suggest Murray threw the match away after coming back from 2-5 in the fifth set and failing to convert any of three break points that would have left him serving for the match.
(6) If you haven’t seen it,” Clinton said, “you need to see her speech in New Hampshire.” Michelle Obama denounces Trump's rhetoric: 'It has shaken me to my core' Read more In fact, Obama’s oratory was a Clinton campaign highlight Thursday, a much-shared, widely tweeted and overwhelmingly celebrated defense of girls’ and women’s rights not to be demeaned or assaulted by anyone, not a construction worker on the street or the man who would be president.
(7) I’m not surprised that conservatives are using degrading language or demeaning the movement.
(8) Ed Balls, the shadow chancellor, accused Osborne of demeaning his office.
(9) We were very relieved and pleased, but the whole process was costly and demeaning.
(10) He is at least as tribal, jingoistic, and provincial as those he condemns for those human failings, as he constantly hails the nobility of his side while demeaning those Others.
(11) I felt it was demeaning for TB if GB was seen as the giant figure and he was Mr public services, Mr crisis management, Mr international tootling-along-behind.
(12) Trump approves of working with autocrats, at least, and would probably make fast friends with the galaxy’s less reputable leaders – especially those who share his interests, eg crimelord Jabba the Hutt, who lives in an ostentatious palace , loves parties , demeans women and feeds a literal Rancor .
(13) Little more than 50 years on, however, it is the setting for a chaotic and demeaning political battle that has even long-term parliament watchers shaking their heads in disbelief.
(14) The strategy backfired within hours because, with just a few sentences, Miliband gave a truly prime ministerial rebuttal: “Michael Fallon’s a decent man but today I think he has demeaned himself and he’s demeaned his office.
(15) Usually this is stuff I can ignore but don’t demean sufferers, don’t twist my words, back the fuck up bros.
(16) "I say to them, you will never ever appease the rightwing media and to try demeans you and our party."
(17) Facebook Twitter Pinterest Cameron accused of waffling by English Literature student Giles Fraser: ‘Cameron doesn’t have a higher vision than the price of the pound’ Oh, how the prime minister has demeaned the high calling of his office.
(18) Facebook Twitter Pinterest New York's Metropolitan Transit Authority originally ruled that the posters were demeaning and would not be permitted in the city's subways, but allowed them after the anti-Muslim group took the agency to court.
(19) Union representatives have insisted the project is simply meant to draw political attention to the increase in homelessness , and is in no way intended to demean or humiliate homeless people.
(20) The real answer behind this sorry tale could be that Trierweiler could not deal with the demeaning role of presidential PR prop and public property that the role of Premiere Dame, or any kind of political wife now involves.