(v. t.) To blot out; to erase; to expunge; to dele; to omit.
Example Sentences:
(1) Moreover, homozygous deletion of the FMS gene may be an important event in the genesis of the MDS variant 5q- syndrome.
(2) None of the 4NQO- or 4HAQO-induced mutants is a multilocus deletion mutant.
(3) In strains completely deleted for galR, the gene which encodes the Gal repressor, the operon is derepressed by only 10-fold without an inducer.
(4) Delta roc, which extends from base pairs 41883 to 43825, overlaps the nin5 deletion, which extend from base pairs 40501 to 43306.
(5) The deletions and substitutions appear to occur in separate molecules.
(6) By external deletion, we have identified RXE composed of 205 nucleotides.
(7) A 6.4 kilobase C4B-5'-specific Taq I fragment usually provided a reliable guide to the presence of a C4A deletion but unusually in one instance this fragment was found to be a marker of a functioning C4A gene.
(8) Three distinct antigenic regions of bovine somatotropin (bST) were identified on the basis of the ability of a set of monoclonal antibodies to bind to proteolytic fragments and deletion variants of recombinant bST (rbST) in Western blot analyses.
(9) Analysis of glutamate dehydrogenase (GDH) expression by enzyme assay and immunoblots, as well as Northern and dot blots of poly (A)+ RNA, in the deletion strains indicates that there are two upstream regulatory sequences that control the level of gene expression.
(10) Analysis of genetic markers associated with the deleted haplotypes pointed to the independent origin of similar deletions and the involvement of intergenic sequences in the mispairing-recombination process.
(11) Cells transfected with either the first or second construct and selected for the TK+ phenotype were then tested for TK induction after superinfection with HSV-1(F) delta 305, containing a deletion in the coding sequences of the TK gene, and viruses containing, in addition, a ts lesion in the alpha 4 regulatory protein (ts502 delta 305) or in the beta 8 major DNA-binding protein (tsHA1 delta 305).
(12) No 7 beta-hydroxysteroid dehydrogenase activity and only a trace of 7 alpha-hydroxysteroid dehydrogenase activity could be demonstrated when bile acid was deleted from the growth medium.
(13) All four human MBP variants were identical except for the insertion of deletion of two peptide fragments corresponding to those encoded by exons 2 and 5 of the MBP gene.
(14) Molecular analysis of HPRT- mutant DNAs showed a high frequency (69%) of clones with partial or full deletions of the hprt gene among radiation-induced mutants compared with spontaneous mutants (31%).
(15) Reciprocal translocations involving the short arm of acrocentric chromosomes can segregate to produce partial duplications without associated deletions.
(16) Considering those portions of the molecule that can be deleted without a loss of catalytic activity, one is left with a catalytic center of approximately 130 nucleotides that is solely responsible for the molecule's activity.
(17) Twenty-nine deletion breakpoints were mapped in 220 kb of the DXS164 locus relative to potential exons of the Duchenne and Becker muscular dystrophy gene.
(18) Then these two repeats were separated and deleted systematically to obtain various deletions.
(19) Although T cell tolerance to self antigens is primarily a reflection of clonal deletion in the thymus, recent evidence suggests that mature T cells are subject to negative regulation in the post-thymic environment: Extrathymic tolerance is the result of clonal anergy in some studies and T cell deletion in others.
(20) We report two cases of leiomyomas of the uterus with a deletion of the long arm of chromosome 13.
Key
Definition:
(n.) An instrument by means of which the bolt of a lock is shot or drawn; usually, a removable metal instrument fitted to the mechanism of a particular lock and operated by turning in its place.
(n.) An instrument which is turned like a key in fastening or adjusting any mechanism; as, a watch key; a bed key, etc.
(n.) That part of an instrument or machine which serves as the means of operating it; as, a telegraph key; the keys of a pianoforte, or of a typewriter.
(n.) A position or condition which affords entrance, control, pr possession, etc.; as, the key of a line of defense; the key of a country; the key of a political situation. Hence, that which serves to unlock, open, discover, or solve something unknown or difficult; as, the key to a riddle; the key to a problem.
(n.) That part of a mechanism which serves to lock up, make fast, or adjust to position.
(n.) A piece of wood used as a wedge.
(n.) The last board of a floor when laid down.
(n.) A keystone.
(n.) That part of the plastering which is forced through between the laths and holds the rest in place.
(n.) A wedge to unite two or more pieces, or adjust their relative position; a cotter; a forelock.
(n.) A bar, pin or wedge, to secure a crank, pulley, coupling, etc., upon a shaft, and prevent relative turning; sometimes holding by friction alone, but more frequently by its resistance to shearing, being usually embedded partly in the shaft and partly in the crank, pulley, etc.
(n.) An indehiscent, one-seeded fruit furnished with a wing, as the fruit of the ash and maple; a samara; -- called also key fruit.
(n.) A family of tones whose regular members are called diatonic tones, and named key tone (or tonic) or one (or eight), mediant or three, dominant or five, subdominant or four, submediant or six, supertonic or two, and subtonic or seven. Chromatic tones are temporary members of a key, under such names as " sharp four," "flat seven," etc. Scales and tunes of every variety are made from the tones of a key.
(n.) The fundamental tone of a movement to which its modulations are referred, and with which it generally begins and ends; keynote.
(n.) Fig: The general pitch or tone of a sentence or utterance.
(v. t.) To fasten or secure firmly; to fasten or tighten with keys or wedges.
Example Sentences:
(1) Community involvement is a key element of the Primary Health Care (PHC) approach, and thus an essential topic on a course for managers of Primary Health Care programmes.
(2) A key way of regaining public trust will be reforming the system of remuneration as agreed by the G20.
(3) Instead, the White House opted for a low-key approach, publishing a blogpost profiling Trinace Edwards, a brain-tumour victim who recently discovered she was eligible for Medicaid coverage.
(4) The presence of a few key residues in the amino-terminal alpha-helix of each ligand is sufficient to confer specificity to the interaction.
(5) The key warning from the Fed chair A summary of Bernanke's hearing Earlier... MPs in London quizzed the Bank of England on Libor.
(6) "Seller reports are key to identifying bad buyers and ridding them from our marketplace," says eBay.
(7) It is suggested that the low-density lipoprotein receptors in human fetal liver may play a key role in the regulation of the serum cholesterol levels during gestation.
(8) A key component of a career program should be recognition of a nurse's needs and the program should be evaluated to determine if these needs are met.
(9) As novel antibody therapeutics are developed for different malignancies and require evaluation with cells previously uncharacterized as antibody-dependent cell-mediated cytotoxicity (ADCC) targets, efficient description of key parameters of the assay system expedites the preclinical assessment.
(10) Meanwhile, Hunt has been accused of backtracking on a key recommendation in the official report into Mid Staffs.
(11) The safe motherhood initiative demands an intersectoral, collaborative approach to gynecology, family planning, and child health in which midwifery is the key element.
(12) Acetylcholinesterase is a key enzyme in cholinergic neurotransmission for hydrolyzing acetylcholine and has been shown to possess arylacylamidase activity in addition to esterase activity.
(13) If Lagarde had been placed under formal investigation in the Tapie case, it would have risked weakening her position and further embarrassing both the IMF and France by heaping more judicial worries on a key figure on the international stage.
(14) Four goals, four assists, and constant movement have been a key part of the team’s success.
(15) Mechanosensitive ion channels may play a key role in transducing vascular smooth muscle (VSM) stretch into active force development.
(16) But Abaaoud, the man thought to be a key planner for the group behind the Paris attacks, boasted to a niece that he had brought around 90 militants back to Europe with him.
(17) Key therapeutic questions are whether beta-lactams can safely replace aminoglycosides for the treatment of gram-negative pneumonia, and whether monotherapy or aminoglycoside and beta-lactam combination antibiotic treatment is superior.
(18) Teaching procedures then establish and build these key components to fluency.
(19) Doubts about Hinkley Point have deepened after a detailed report by HSBC’s energy analysts described eight key challenges to the project, which will be built by the state-backed French firm EDF and be part-financed by investment from China .
(20) The Lords will vote on three key amendments: • To exclude child benefit from the cap calculation (this would roughly halve the number of households affected).