(v. t.) To blot out; to erase; to expunge; to dele; to omit.
Example Sentences:
(1) Moreover, homozygous deletion of the FMS gene may be an important event in the genesis of the MDS variant 5q- syndrome.
(2) None of the 4NQO- or 4HAQO-induced mutants is a multilocus deletion mutant.
(3) In strains completely deleted for galR, the gene which encodes the Gal repressor, the operon is derepressed by only 10-fold without an inducer.
(4) Delta roc, which extends from base pairs 41883 to 43825, overlaps the nin5 deletion, which extend from base pairs 40501 to 43306.
(5) The deletions and substitutions appear to occur in separate molecules.
(6) By external deletion, we have identified RXE composed of 205 nucleotides.
(7) A 6.4 kilobase C4B-5'-specific Taq I fragment usually provided a reliable guide to the presence of a C4A deletion but unusually in one instance this fragment was found to be a marker of a functioning C4A gene.
(8) Three distinct antigenic regions of bovine somatotropin (bST) were identified on the basis of the ability of a set of monoclonal antibodies to bind to proteolytic fragments and deletion variants of recombinant bST (rbST) in Western blot analyses.
(9) Analysis of glutamate dehydrogenase (GDH) expression by enzyme assay and immunoblots, as well as Northern and dot blots of poly (A)+ RNA, in the deletion strains indicates that there are two upstream regulatory sequences that control the level of gene expression.
(10) Analysis of genetic markers associated with the deleted haplotypes pointed to the independent origin of similar deletions and the involvement of intergenic sequences in the mispairing-recombination process.
(11) Cells transfected with either the first or second construct and selected for the TK+ phenotype were then tested for TK induction after superinfection with HSV-1(F) delta 305, containing a deletion in the coding sequences of the TK gene, and viruses containing, in addition, a ts lesion in the alpha 4 regulatory protein (ts502 delta 305) or in the beta 8 major DNA-binding protein (tsHA1 delta 305).
(12) No 7 beta-hydroxysteroid dehydrogenase activity and only a trace of 7 alpha-hydroxysteroid dehydrogenase activity could be demonstrated when bile acid was deleted from the growth medium.
(13) All four human MBP variants were identical except for the insertion of deletion of two peptide fragments corresponding to those encoded by exons 2 and 5 of the MBP gene.
(14) Molecular analysis of HPRT- mutant DNAs showed a high frequency (69%) of clones with partial or full deletions of the hprt gene among radiation-induced mutants compared with spontaneous mutants (31%).
(15) Reciprocal translocations involving the short arm of acrocentric chromosomes can segregate to produce partial duplications without associated deletions.
(16) Considering those portions of the molecule that can be deleted without a loss of catalytic activity, one is left with a catalytic center of approximately 130 nucleotides that is solely responsible for the molecule's activity.
(17) Twenty-nine deletion breakpoints were mapped in 220 kb of the DXS164 locus relative to potential exons of the Duchenne and Becker muscular dystrophy gene.
(18) Then these two repeats were separated and deleted systematically to obtain various deletions.
(19) Although T cell tolerance to self antigens is primarily a reflection of clonal deletion in the thymus, recent evidence suggests that mature T cells are subject to negative regulation in the post-thymic environment: Extrathymic tolerance is the result of clonal anergy in some studies and T cell deletion in others.
(20) We report two cases of leiomyomas of the uterus with a deletion of the long arm of chromosome 13.
Squelch
Definition:
(v. t.) To quell; to crush; to silence or put down.
(n.) A heavy fall, as of something flat; hence, also, a crushing reply.
Example Sentences:
(1) What was shaping a week ago to be the second successive, evenly balanced and see-saw NBA finals between these teams instead proved shockingly one-sided, as Miami were squelched for the third time in six days and lost the best-of-seven series by four games to one.
(2) The effects of the amplitude of the squelch signal and of the degree of smoothing were systematically investigated for experimental and simulated 1-D and 2-D rf echograms.
(3) In Beijing I witnessed recently how the only Chinese demonstration against the war was squelched by police, while a march by foreign residents was tolerated for just 20 minutes.
(4) The ability of the c-Jun protein, the main component of the transcription factor AP1, to interact directly or indirectly with the RNA polymerase II-initiation complex to activate transcription was investigated by in vivo transcription interference ("squelching") experiments.
(5) The GAL-TAF-1 activator was found to self-squelch without affecting basal transcription.
(6) The emerging popularity of the procedure was squelched by the frequent complication of gastrojejunal stomal ulceration.
(7) Zhou established Fengrui in 2007 and the next year took on one of the country’s biggest dairies in a scandal over tainted baby formula that the government had tried to squelch.
(8) Here, we provide evidence that EB1 and R can synergistically activate specific transcription, and that overexpressed, unbound EB1, represses the R-induced transcription ('squelching').
(9) We have to watch for and cultivate and encourage those glimmers of curiosity and possibility, not suppress them, not squelch them,” Obama told the audience on the South Lawn, which included astronauts, scientists and students.
(10) Interestingly, at high concentrations human jun-D displays decreased activity which cannot be explained by a simple self squelching model.
(11) These purified cofactors were found to be required for CTF-1-regulated transcription, and they counteracted squelching by an excess of activator in in vitro reconstitution experiments.
(12) We don’t go around that way when there are big tides,” I was told with unblinking frankness as I squelched up to my hotel reception desk.
(13) When excess v-jun is expressed in the cell, replication is inhibited or 'squelched'.
(14) We suggest that this inhibition, which we call squelching, reflects titration of a transcription factor by the activating region of GAL4.
(15) A similar level of squelching was seen after removal of the up-stream activation sequences from the yeast reporter gene, suggesting that the squelching interactions were with transcription factors needed for the activity of a basal promoter.
(16) Worse yet, some will demand they be violently squelched, as Brazilian soccer great Ronaldo did when he suggested that police crack down on masked vandals: "I think they have to bring down the clubs, get them off the street."
(17) These images are termed according to their algorithms: ZCS, zero crossing counter with squelch; ASS, analytic signal with squelch; ASW, analytic signal with Wiener kernel; UNP, unwrapped phase; and SAS, smoothed analytic signal.
(18) Once, this place may have been a shit-hole, but it was teeming, hopping, crowded" – and we squelch our way past Desolation Row to a little corner of Cairns Street where the resolute people remain.
(19) These findings suggest that saturation of the cellular capacity to mediate an estrogen response and ER-dependent squelching occur at receptor titers well above those encountered in nature.
(20) An incision was made to remove the abscess, but instead of finding pus, massive bleeding ensued whose source could not be located; it was squelched by tampons.