(v. t.) To point out; to show; to exhibit; to make evident.
(v. t.) To show, or make evident, by reasoning or proof; to prove by deduction; to establish so as to exclude the possibility of doubt or denial.
(v. t.) To exhibit and explain (a dissection or other anatomical preparation).
Example Sentences:
(1) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
(2) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(3) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(4) Of the patients 73% demonstrated clinically normal sensibility test results within 23 days after operation.
(5) Lucy and Ed will combine coverage of hard and breaking news with a commitment to investigative journalism, which their track record so clearly demonstrates”.
(6) These immunocytochemical studies clearly demonstrated that cells encountered within the fibrous intimal thickening in the vein graft were inevitably smooth muscle cell in origin.
(7) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(8) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(9) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(10) Intravesical BCG is clearly superior to oral BCG, and controlled studies have demonstrated that percutaneous administration is not necessary.
(11) We have previously shown that serotonin is present in secretory granules of frog adrenochromaffin cells; concurrently, we have demonstrated that serotonin is a potent stimulator of corticosterone and aldosterone secretion by adrenocortical cells.
(12) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(13) The results demonstrated that K2PtCl4 was bound to a greater degree than CDDP in this system with 3-5 and 1-2 platinum atoms respectively, bound per transferrin molecule.
(14) These studies, in addition to demonstrating that the placenta contains TRH deamidase activity, suggest that losses of fetal TRH through the placenta are not large.
(15) Light microscopic studies of pancreata from mice sacrificed at this time demonstrated insulitis and beta cell necrosis.
(16) Western blot analysis of these mitochondria using an antibody against carnitine palmitoyltransferase II purified from beef heart demonstrates a 68-kDa protein, which under ischemic conditions apparently is decreased by 2 kDa.
(17) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(18) In 1 of the 3, anterior capsular detachment was also demonstrated radiographically and confirmed surgically.
(19) This result demonstrates that branching enzyme belongs to a family of the amylolytic enzymes.
(20) Histological studies of nerves 2 years following irradiation demonstrated loss of axons and myelin, with a corresponding increase in endoneurial, perineurial, and epineurial connective tissue.
Sharpen
Definition:
(a.) To make sharp.
(a.) To give a keen edge or fine point to; to make sharper; as, to sharpen an ax, or the teeth of a saw.
(a.) To render more quick or acute in perception; to make more ready or ingenious.
(a.) To make more eager; as, to sharpen men's desires.
(a.) To make more pungent and intense; as, to sharpen a pain or disease.
(a.) To make biting, sarcastic, or severe.
(a.) To render more shrill or piercing.
(a.) To make more tart or acid; to make sour; as, the rays of the sun sharpen vinegar.
(a.) To raise, as a sound, by means of a sharp; to apply a sharp to.
(v. i.) To grow or become sharp.
Example Sentences:
(1) This paper employs a rhetorical form designed to clarify and sharpen the focus of the very special stance required--which must be painstakingly learned under careful supervision--in order to effectively tune in to communications coming from the unconscious of the patient.
(2) Although not all reported unconventional applications of antimicrobial agents remain in use, sharpening awareness of their multifaceted actions should encourage broader understanding of all agents traditionally confined to specific uses.
(3) The surprise return of Saleh last month, after recovering in Saudi Arabia from an assassination attempt, has plunged the country into deeper uncertainty and sharpened the differences between pro- and anti-government camps.
(4) Ear-piercing techniques include needles, safety pins, sharpened studs, and self-piercing kits.
(5) The factory sharpened scalers exhibited metallic extensions from the lateral surface (wire edges).
(6) Disruption of visual activity, either by blocking activity with intraocular tetrodotoxin (TTX; Schmidt and Edwards, 1983) or by synchronizing activity with strobe illumination (Schmidt and Eisele, 1985), disrupts the sharpening process: the map is correctly oriented but the multiunit receptive fields at each point average 25-40 degrees in diameter.
(7) NaOH or 1 M acetate buffer at pH 6.0 sharpened e.p.r.
(8) The addition of 1 mM MgATP leads to a sharpening of the length distribution around 1.5 micron without change in the 16 nm diameter.
(9) During this period, the intensity of transcription in presomitic and somitic mesoderm declines relative to that in the overlying neural ectoderm, and the transcription boundary within the presumptive hindbrain region sharpens.
(10) The overall sense is of YouTube sharpening its focus on its most popular content, both in terms of individual channels and entire categories.
(11) The day before the murder you Adebolajo bought five knives and a knife sharpener – which you used to sharpen some of the knives in preparation for their use in the murder.
(12) The sharpening dispute over the Senkaku islands, known as Diaoyu in China , is the most recent product of this old narrative of violence, hatred, fear and grief that continues, sporadically, to obstruct both nations in their efforts to forge a more stable, trusting relationship.
(13) Hagan himself used to work in the car industry, and brought a similar shift operation and level of automation to the housing factory to sharpen up the process.
(14) Jam is often used but this can make it too sweet – if you do use jam try mixing in a little lemon juice to sharpen things up.
(15) By the time the latest spat came before the FCC, Karr argues, net activists had sharpened their tactics and raised their game.
(16) To improve the definitions, eliminate overlapping diagnostic categories, and sharpen the fuzzy boundaries that contribute substantially to limited reproducibility, we suggest: (1) the categories of astrocytoma nos, fibrillary astrocytoma, and protoplasmic astrocytoma be collapsed into a single category of astrocytoma; (2) the diagnostic category of desmoplastic medulloblastoma be combined with medulloblastoma; and (3) the criteria for anaplasia should be further refined to include quantification of critical histologic features, e.g., agreed upon operational definitions for amount of cell density, number of mitoses and pleomorphism for anaplastic astrocytoma and anaplastic ependymoma.
(17) Rather than pointing fingers or assigning blame, let’s use this occasion to expand our moral imaginations, to listen to each other more carefully, to sharpen our instincts for empathy and remind ourselves of all the ways that our hopes and dreams are bound together … If this tragedy prompts reflection and debate – as it should – let’s make sure it’s worthy of those we have lost.
(18) When sharpened with citrus and lubricated with olive oil, this is a real delight.
(19) His friend Dingle Foot drafted an editorial that David then sharpened up, inserting phrases that summed up his outlook: 'We had not realised that our government was capable of such folly and crookedness...It is no longer possible to bomb countries because you fear that your trading interests will be harmed...this new feeling for the sanctity of human life is the best element in the modern world.'
(20) The temperature profiles of turbidity (TP tau) of the cyclododecapeptide are analogous to those of the polyhexapeptide where increases in concentration lead to translations of the profiles to lower temperature without sharpening of the transition.