(a.) Having the constituent parts massed or crowded together; close; compact; thick; containing much matter in a small space; heavy; opaque; as, a dense crowd; a dense forest; a dense fog.
(a.) Stupid; gross; crass; as, dense ignorance.
Example Sentences:
(1) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(2) In spite of dense lymphocytic infiltration only 3% of the tumor infiltrating lymphocytes exhibit the activation marker CD 25.
(3) Immunogold electron microscopy demonstrated that outer dense fibres were the predominant immunoreactive site.
(4) Electron microscopy revealed the presence of a hitherto unreported peculiar "pilovacuolar" inclusion in numerous mitochondria, composed of an electron dense pile or rod within a vacuole, while globular or crystalline inclusions were absent.
(5) A recent report suggested that neurons in the prefrontal, anterior cingulate, and primary motor cortex of the brains of schizophrenic subjects may be less dense than those in the brains of nonschizophrenic subjects.
(6) Two years ago, the Intergovernmental Panel on Climate Change declared Egypt's Nile Delta to be among the top three areas on the planet most vulnerable to a rise in sea levels, and even the most optimistic predictions of global temperature increase will still displace millions of Egyptians from one of the most densely populated regions on earth.
(7) Chick sympathetic nerve fibers densely innervate expansor secundariorum muscle, but not skeletal muscle.
(8) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(9) In the first assay, we used a simple density separation technique to remove dense neutrophils (PMN) from suspensions of blood and of bone marrow cells prior to culture in semisolid agar.
(10) In contrast to the defect in another packaging-deficient mutant ts1201, the block in the formation of dense-cored, DNA-containing capsids in ts1233-infected cells at the NPT could not be reversed by transferring the cells to the permissive temperature in the presence of a protein synthesis inhibitor.
(11) The outstanding morphologic feature of cortical cells exposed to microunit ACTH concentrations for 40 min was the abundance of electron-dense granules (0.2-0.4 mum).
(12) The majority of intensively stained and densely packed cells have been observed in tv nucleus.
(13) The wall of the yolk sac thickens as a result of this infolding and the densely packed capillaries.
(14) Viral particles in the cultures and the brain were of various sizes and shapes; particles ranged from 70 to over 160 nm in diameter, with a variable position of dense nucleoids and less dense core shells.
(15) Martin O’Neill spoke of his satisfaction at the Republic of Ireland’s score draw in the first leg of their Euro 2016 play-off against Bosnia-Herzegovina – and of his relief that the match was not abandoned despite the dense fog that descended in the second half and threatened to turn the game into a farce.
(16) Phagosomes and dense bodies reminiscent of Russel bodies also occurred in the Mikulicz cells, in the vacuoles of which formations representing Klebsiella rhinoscleromatis were demonstrated.
(17) Electron microscopic examination of all leptomeningeal and meningioma cultures revealed desmosomes and dense tonofilament formation; in addition, granular, filamentous basement membrane-like material was abundant in the extracellular spaces of all cultures.
(18) Genes of the baker's yeast Saccharomyces cerevisiae are densely clustered on 16 linear chromosomes.
(19) The results suggest that the conversion of the HRP-TMB reaction product to an electron-dense form during osmication is intimately associated with the pH of the phosphate buffer and the total time of osmication.
(20) Chemical binding studies showed that the teichoic acid was the major uranyl binding component in isolated walls, from which it might be inferred that teichoic acid was located in the densely staining regions.
Tough
Definition:
(superl.) Having the quality of flexibility without brittleness; yielding to force without breaking; capable of resisting great strain; as, the ligaments of animals are remarkably tough.
(superl.) Not easily broken; able to endure hardship; firm; strong; as, tough sinews.
(superl.) Not easily separated; viscous; clammy; tenacious; as, tough phlegm.
(superl.) Stiff; rigid; not flexible; stubborn; as, a tough bow.
(superl.) Severe; violent; as, a tough storm.
Example Sentences:
(1) Photograph: Guardian The research also compiled data covered by a wider definition of tax haven, including onshore jurisdictions such as the US state of Delaware – accused by the Cayman islands of playing "faster and looser" even than offshore jurisdictions – and the Republic of Ireland, which has come under sustained pressure from other EU states to reform its own low-tax, light-tough, regulatory environment.
(2) Nick Robins, head of the Climate Change Centre at HSBC, said: "If you think about low-carbon energy only in terms of carbon, then things look tough [in terms of not using coal].
(3) A series of hierarchical multiple regressions revealed the effects of Surgency, Agreeableness, Conscientiousness, Emotional Stability, and Intellect on evoking upset in spouses through condescension (e.g., treating spouse as stupid or inferior), possessiveness (demanding too much time and attention), abuse (slapping spouse), unfaithfulness (having sex with others), inconsiderateness (leaving toilet seat up), moodiness (crying a lot), alcohol abuse (drinking too much alcohol), emotional constriction (hiding emotions to act tough), and self-centeredness (acting selfishly).
(4) A lfred Ekpenyong knows first hand how tough it can be to find a secure foothold in mainstream society after leaving prison.
(5) The texture of a food item can be distinguished in hardness, toughness, stickiness, juiciness and chewability.
(6) Even as the Obama administration moves to deal with some of Guantánamo's most notorious captives, it faces tough challenges to closing the facility.
(7) "It's a tough group but other groups are also tough.
(8) This allowed it to claim that it was becoming more professional, tough minded and responsible.
(9) The austerity programmes administered by western governments in the wake of the 2008 global financial crisis were, of course, intended as a remedy, a tough but necessary course of treatment to relieve the symptoms of debts and deficits and to cure recession.
(10) And he pleased the audience with an acknowledgement that social work is a tough job and social workers only human.
(11) Trade unions have sought to highlight the insecurity of workers who have been forced into self-employment in the tough jobs market of recent years.
(12) UK negotiatiors, though, fought back hard -- thus Cameron's fighting talk in his press conference ( see 12.46pm ) 12.49pm BST Open Europe tweets Cameron's tough talk on the rebate: Open Europe (@OpenEurope) Cameron: in Feb we reached a clear deal rebate would remain unchanged, since then some have tried to question this agreement June 28, 2013 Open Europe (@OpenEurope) Cameron: I defeated these attempts to change the rebate, it will remain unchanged for this long term budget June 28, 2013 12.46pm BST David Cameron press conference underway In Brussels, David Cameron is holding his press conference now.
(13) The mechanical properties of compressed beam specimens of microcrystalline cellulose (Avicel pH 101) have been assessed in terms of the tensile strength (sigma t), Young's modulus (E) and the following fracture mechanics parameters: the critical stress intensity factor (KIC), the critical strain energy release rate (GIC) and the fracture toughness (R).
(14) "2013 was a tough year for us both in minerals and in oil and gas," Cochrane said, adding that the group had relied on"self help", including diversification which offset some of the challenges in its core mining market, improving operational efficiency, and strong growth in its after sales business, where orders were up 16% on 2012 and which accounted for 63% of revenues last year.
(15) "We carved out a few chances, but it was tough to break them down."
(16) Channel 5 will be hoping for a similar return for its new series, although with the launch audience around a third down on last year's opener, it may prove a tough ask.
(17) Dimon, the charismatic leader of the bank, had enjoyed a reputation as a tough, strict taskmaster, the kind of CEO every bank should have.
(18) Cameron put all of his betting chips on what seemed to be the party's trump card: the "vote for us, we're tough on migration and tough on migrants" strategy.
(19) As well as limited terms for MPs, Grillo has called for a referendum on the euro and a tough line on immigration.
(20) "It's a tough game but our best football has come in this competition and we'll try and show it next week.