(a.) Disordered; especially, disordered in mind; crazy; insane.
Example Sentences:
(1) It is not known whether the deposits are primary or secondary events, but they may be of importance in initiating or maintaining derangement in heart function.
(2) All of them had fever, jaundice, abdominal pain, leucocytosis and deranged liver function while 26.6% were in shock, 13.3% in coma and 40% in azotaemia.
(3) In patients with Cushing's disease or Nelson's syndrome ACTH secretion is insensitive to naloxone, presumably because of an autonomous pituitary adenoma or hypothalamic derangement.
(4) The high ratio observed in BALF from patients with sarcoidosis and a chronic derangement of alveolar structure suggests either an increased C2 production or an alternative complement pathway (C2-independent) activation within their lungs.
(5) Progress is our understanding of the roles of vasogenic and cytotoxic brain edema in secondary brain damage can be expected from studies of the ability of biochemical factors to open the blood-brain barrier, derange the microcirculation, and cause cell swelling and necrosis.
(6) We assert that OCD and AVN are relatively common, clinically significant lesions of the mandibular condyle often associated with preexisting internal derangement of the temporomandibular joint.
(7) A hypothesis is presented as to how certain occlusal relationships and habitual patterns of jaw use may predispose an individual to TMJ internal derangements.
(8) These data suggest the feasibility of using calcium and EDTA infusions combined with an intact PTH assay to define the relationships between circulating levels of PTH-(1-84) and calcium in states of normal and deranged parathyroid physiology.
(9) Functionally, the first component reflected 55% of the reducibility property and an unimpaired oxidizability property, while the latter exhibited derangement of both aspects of cytochrome c activity.
(10) Laboratory investigations revealed hyperbilirubinemia, marked increase in serum transaminases, a variable alkaline phosphatase level and electrolytes derangement.
(11) Understanding how steroids work has led to improved comprehension of such derangements of hormonal regulation as testicular feminization.
(12) A case of a patient with a malignant schwannoma, who was originally diagnosed as having internal derangement of the temporomandibular joint (TMJ), is presented.
(13) The consequence of these derangements is often widespread plugging of small bronchi and bronchioles.
(14) The deranged adenosine metabolism and raised cAMP in the platelets of this child with severe combined immunodeficiency may explain the altered response to ADP.
(15) Surgery has been important in the treatment of internal derangement of the TMJ.
(16) Biopsies of lumbar multifidus muscles were obtained at operation on seventeen patients aged from fifteen to fifty-eight with lumbar spinal derangement, and further material was taken from the cadavers of three subjects aged from nineteen to fifty-one.
(17) Infection, compression and metabolic derangement were implicated as the most common etiologic factors.
(18) The rate of decline of creatinine clearance, the changes of the urinary protein loss, of total serum protein, of the daily insulin requirement, of the nutritional status and of some hormonal derangements were examined.
(19) Respiratory and circulatory derangements and brain damage ensue if the problem is not promptly recognized and corrected.
(20) It has been suggested that the occurrence of an intracellular Ca2+ overload may result in the development of diabetic cardiomyopathy, which is associated with depletion of high-energy phosphate stores and a derangement of ultrastructure and cardiac dysfunction.
Twisted
Definition:
(imp. & p. p.) of Twist
(a.) Contorted; crooked spirally; subjected to torsion; hence, perverted.
Example Sentences:
(1) Aberrant forms (elongated and twisted) in the vacuole and double virions in the plasma membrane were observed as early as 65 h after infection.
(2) Electron microscopy shows that at neutral pH, CEA particles consist of homogeneous, morphologically distinctive, twisted rod-shaped particles, about 9 X 40 nm.
(3) Rapid swelling of the knee following a blow or twisting injury is considered a significant injury.
(4) Intermolecular contacts occur in both oligomers in the minor groove: in the B form through twisted guanine-guanine hydrogen bonding, and in the Z form through base-base stacking and the water network.
(5) Ings twisted the knee during his first training session with Klopp in charge and tests have shown the former Burnley forward ruptured an anterior cruciate ligament, meaning that a player who has just broken into England’s senior team will be out for a minimum of six months.
(6) Leicester looked a little sorry for themselves and, with their concentration down, United twisted the knife.
(7) Gowher Rizvi, chief representative of the prime minister, Sheik Hasina, told the Guardian that preparations for the forthcoming elections, were "completely on track" and that the tribunal, probing crimes committed during the 1971 war in which Bangladesh broke away from Pakistan, was about bringing justice previously denied by "the twists and turns" of the country's history.
(8) The base orientations are characterized by a substantial inclination and propellor twist.
(9) Among the non-standard postures examined were: twisting while lifting or lowering, lifting and lowering from lying, sitting, kneeling, and squatting positions, and carrying loads under conditions of constricted ceiling heights.
(10) A vicious feud playing out within Uzbekistan's ruling family took a new twist on Monday , when prosecutors announced that the clan's most flamboyant member faces charges of involvement in mafia-style corruption.
(11) The possible arrangements of molecules within the twisted ribbons have been deduced and are found to be fairly closely related.
(12) Idiopathic torsion dystonia (ITD) is characterized by sustained, involuntary muscle contractions, frequently causing twisting and repetitive movements or abnormal postures.
(13) These results indicate that the polypeptide chain, driven by energetics (nonbonded and electrostatic interactions), is folded into a typical left-handed twisted four-helix bundle with an approximately 4-fold symmetric array, as observed in most four alpha-helix proteins.
(14) In the mutants twist and snail, which fail to differentiate the ventrally derived mesoderm, mitoses specific to the mesoderm are absent.
(15) Fulham were helped by United being forced into a trio of substitutions at the interval, as Rafael succumbed to a twisted ankle, Cleverly had double vision and Evans had back trouble.
(16) Blockage of the balloon system was possibly caused by twisting the system to reach and pass the lesion in the branch of left circumflex coronary artery.
(17) In the tradition of the American author Patricia Highsmith, creator of the charming psychopath Tom Ripley, Rendell used twisting plots to expose twisted minds.
(18) From previous genetic and biochemical studies it was hypothesized that dorsal might be responsible for the activation of the zygotic gene twist.
(19) Finally, the twisted nose was treated by freeing the nasal components, straightening the bone and cartilage, and replacing them in their anatomical positions.
(20) It doesn’t do a lot at the moment, but there’s a lot of potential for a modern twist on board games here.