(a.) Disordered; especially, disordered in mind; crazy; insane.
Example Sentences:
(1) It is not known whether the deposits are primary or secondary events, but they may be of importance in initiating or maintaining derangement in heart function.
(2) All of them had fever, jaundice, abdominal pain, leucocytosis and deranged liver function while 26.6% were in shock, 13.3% in coma and 40% in azotaemia.
(3) In patients with Cushing's disease or Nelson's syndrome ACTH secretion is insensitive to naloxone, presumably because of an autonomous pituitary adenoma or hypothalamic derangement.
(4) The high ratio observed in BALF from patients with sarcoidosis and a chronic derangement of alveolar structure suggests either an increased C2 production or an alternative complement pathway (C2-independent) activation within their lungs.
(5) Progress is our understanding of the roles of vasogenic and cytotoxic brain edema in secondary brain damage can be expected from studies of the ability of biochemical factors to open the blood-brain barrier, derange the microcirculation, and cause cell swelling and necrosis.
(6) We assert that OCD and AVN are relatively common, clinically significant lesions of the mandibular condyle often associated with preexisting internal derangement of the temporomandibular joint.
(7) A hypothesis is presented as to how certain occlusal relationships and habitual patterns of jaw use may predispose an individual to TMJ internal derangements.
(8) These data suggest the feasibility of using calcium and EDTA infusions combined with an intact PTH assay to define the relationships between circulating levels of PTH-(1-84) and calcium in states of normal and deranged parathyroid physiology.
(9) Functionally, the first component reflected 55% of the reducibility property and an unimpaired oxidizability property, while the latter exhibited derangement of both aspects of cytochrome c activity.
(10) Laboratory investigations revealed hyperbilirubinemia, marked increase in serum transaminases, a variable alkaline phosphatase level and electrolytes derangement.
(11) Understanding how steroids work has led to improved comprehension of such derangements of hormonal regulation as testicular feminization.
(12) A case of a patient with a malignant schwannoma, who was originally diagnosed as having internal derangement of the temporomandibular joint (TMJ), is presented.
(13) The consequence of these derangements is often widespread plugging of small bronchi and bronchioles.
(14) The deranged adenosine metabolism and raised cAMP in the platelets of this child with severe combined immunodeficiency may explain the altered response to ADP.
(15) Surgery has been important in the treatment of internal derangement of the TMJ.
(16) Biopsies of lumbar multifidus muscles were obtained at operation on seventeen patients aged from fifteen to fifty-eight with lumbar spinal derangement, and further material was taken from the cadavers of three subjects aged from nineteen to fifty-one.
(17) Infection, compression and metabolic derangement were implicated as the most common etiologic factors.
(18) The rate of decline of creatinine clearance, the changes of the urinary protein loss, of total serum protein, of the daily insulin requirement, of the nutritional status and of some hormonal derangements were examined.
(19) Respiratory and circulatory derangements and brain damage ensue if the problem is not promptly recognized and corrected.
(20) It has been suggested that the occurrence of an intracellular Ca2+ overload may result in the development of diabetic cardiomyopathy, which is associated with depletion of high-energy phosphate stores and a derangement of ultrastructure and cardiac dysfunction.
Unbalanced
Definition:
(a.) Not balanced; not in equipoise; having no counterpoise, or having insufficient counterpoise.
(a.) Not adjusted; not settled; not brought to an equality of debt and credit; as, an unbalanced account; unbalanced books.
(a.) Being, or being thrown, out of equilibrium; hence, disordered or deranged in sense; unsteady; unsound; as, an unbalanced mind.
Example Sentences:
(1) In a newspaper interview last month, Shapps said the BBC needed to tackle what he said was a culture of secrecy, waste and unbalanced reporting if it hoped to retain the full £3.6bn raised by the licence fee after the current Royal Charter expires in 2016.
(2) The erythrocytes of subjects with moderate and severe alcoholic liver cirrhosis had an unbalanced antioxidant system (normal superoxide dismutase, low catalase and glutathione peroxidase activities, and low glutathione content).
(3) Deletions and unbalanced translocations of the short arm of chromosome 1 also were found in four cases, affecting band p32 in three of them.
(4) This unusual pattern of unbalanced growth may represent an adaptation by bdellovibrios to maximize their progeny yield from the determinate amount of substrate available within a given prey cell.
(5) Using 166 pedigrees, reported in nine series available in the literature (including our own), we conclude that balanced insertion cannot entirely explain the familial data, even if we allow for a reduced viability of unbalanced gametes.
(6) It has prolonged the recession and promoted a lopsided and unbalanced recovery which promises another collapse in the not-distant future.
(7) World economic growth becomes more unbalanced and the terms of trade widen.
(8) Sporulation occurs during the late logarithmic phase of a culture, a time of slow but unbalanced growth.
(9) These results suggest that the motor dysfunctions observed in MNU treated rats are induced by unbalanced output activities from Purkinje cells to motor neurons.
(10) The proportion of spermatozoa with an unbalanced form of the translocation was 53%.
(11) This result, associated with the enlarged flagellar pocket, suggests an unbalanced cytoplasmic exchange between exocytosis and endocytosis.
(12) This is the first example of a paternally-derived PWCR allele loss caused by an unbalanced translocation that has arisen de novo.
(13) In all cases abnormal clones present an apparently unbalanced karyotype, characterised by excess material.
(14) "The private sector and private sector leaders also need to realise that only agreements that are fair and mutually beneficial will stand the test of time because if it is unfair and unbalanced, a new leader will come in and throw it all out.
(15) The unbalanced growth detected in S. cerevisiae NCYC 86 under inositol deprivation might be due to an abnormal functioning of the cell membranes as a consequence of the deficiency in inositol-containing phospholipids.
(16) Complications from ARDS include stress ulcers, which occur when gastric aggressive and defensive functions become unbalanced.
(17) The proposita, carrier of the unbalanced form of the translocation, resulted partially monosomic for short arm of chromosome 8 (8p-) and partially trisomic for short arm of chromosome 13.
(18) Cytogenetic studies on a phenotypically normal fertile male revealed an unbalanced Y; 15 translocation.
(19) It is possible that the occurrence of the short period of "unbalanced growth" induced by such DNA damaging agents leads to filament formation.
(20) In language eerily familiar to student politicians across the land, Abetz continued: “The new managing director will inherit an unbalanced and largely centralised public broadcaster which has become a protection racket for the left ideology.” For decades the highly trusted public broadcaster has weathered a relentless stream of attacks by the crusaders of the (increasingly) hard right in Australia.