(a.) Destitute or deprived of inhabitants; deserted; uninhabited; hence, gloomy; as, a desolate isle; a desolate wilderness; a desolate house.
(a.) Laid waste; in a ruinous condition; neglected; destroyed; as, desolate altars.
(a.) Left alone; forsaken; lonely; comfortless.
(a.) Lost to shame; dissolute.
(a.) Destitute of; lacking in.
(v. t.) To make desolate; to leave alone; to deprive of inhabitants; as, the earth was nearly desolated by the flood.
(v. t.) To lay waste; to ruin; to ravage; as, a fire desolates a city.
Example Sentences:
(1) Downtown LA is improving, but for years it was a desolate hell zone of freeways, office blocks and closed stores.
(2) The coast here feels like an island, desolate and full of surprises.
(3) The Eritrean government requires every pupil to complete their final year of high school by serving in Sawa Military Camp, in the desolate, semi-desert region of eastern Eritrea .
(4) But for the next few hours, though, there's little to excite us: Joseph Weisenthal (@TheStalwart) The economic data calendar is a desolate wasteland of nothingness.
(5) When it is not clogged with weekend traffic, Container – the English word is used in Arabic – is a desolate spot: a lonely stretch of asphalt, four dingy tollbooth-like structures painted white and green, a few bored Israeli soldiers with automatic rifles.
(6) They are kept in a small pen behind the Lion's Den, a pub on a ranch in desolate countryside 75 miles south of Johannesburg.
(7) It was after the Indian wars of the 1870s that the indigenous tribes started to be consigned to reservations – on the worst, most desolate lands for grazing or growing crops.
(8) And, Jinkyo-En which was a desolate waste has come to an oasis in life for the Hansenites.
(9) The first time I saw the building - a stark, unapologetically angular silver bunker throwing back the heat of a rather desolate part of Berlin - I was content to register its disturbance without question, submitting to its strategies of oppression and disorientation as a child would.
(10) "Given the complexity of this crisis and the extent of the distress of our people from the north … we must together, I say together, clear the path ahead to free our country from these invaders, who only leave desolation, deprivation and pain in their wake."
(11) And it's Christmas bonanza time along the high streets of Britain, where Oxfam outlets and estate agents lie lonely amid empty sites and desolate closed doors.
(12) Australian visual effects wizard Dave Clayton has been nominated for his work on The Hobbit: The Desolation of Smaug.
(13) But, like many streets in New York City and in cities across the US, it is becoming increasingly desolate.
(14) Season two crafted complex characters racked with existential ambivalence – heroines marked for the abyss, fragile, flammable outcasts and desolate prodigies, all of whose private pain was as palpable as the crimson bloodbath head witch Evelyn Poole soaks in.
(15) Instead, they suggest expanding the scope of services in family planning clinics, out of an awareness that the continuing high prevalence of unintended childbearing, among the young and disadvantaged in particular, is part of a larger problem of living in a desolate social environment.
(16) "I watched this guy brushing off dirt from a skull in the most desolate landscape and right then I just knew," Rincón said of his first encounter with palaeontology.
(17) There was nothing to see for miles but sage-covered high desert, a landscape of stark beauty and eerie desolation.
(18) The contemporary state of the sub-discipline of endocrinology within the framework of internal medicine is generally considered rather desolate, but so far actual data were lacking.
(19) Howell said in July: "There are large uninhabited and desolate areas, certainly up in the north-east where there's plenty of room for fracking well away from anyone's residence where it can be conducted without any kind of threat to the rural environment."
(20) A subroutine called DESOL for the numerical solution of ordinary differential equations of the type arising in biological simulation problems is described.
Dissolute
Definition:
(a.) With nerves unstrung; weak.
(a.) Loosed from restraint; esp., loose in morals and conduct; recklessly abandoned to sensual pleasures; profligate; wanton; lewd; debauched.
Example Sentences:
(1) The agent present in the serum which causes dissolution of the fibrin clot was isolated and identified as pepsinogen.
(2) A 2-fold increase in the dissolution rate was observed when the same number of particles was immobilized without macrophages.
(3) Unaltered surface enamel of extracted human teeth was subjected to tests of resistance to dissolution in 10 mM acetic acid at pH 4.0 and 10 mM EDTA at pH 7.4 in a miniature continuous flow system.
(4) At 30 days after injection both stains revealed cellular debris and glial reactions characteristic of cellular dissolution.
(5) The in vitro dissolution study carried out using dynamic dialysis revealed that the release of adriamycin from these particles follows a bi-phasic pattern.
(6) The retreating rate constants deduced from the dissolution results were well coincident with the values directly determined by the needle penetration method, suggesting good applicability of the proposed equation.
(7) However, in some patients absorption of the drug is markedly sensitive to changes in dissolution rate and new pharmacopoeal standards should not be defined until very rapidly-dissolving formulations have been studied.
(8) Instead, a repetitive, stepwise dissolution pattern was observed.
(9) In ancillary studies, multiple cycles of direct dissolution of UCB crystals revealed a progressive decrease in aqueous solubility of UCB as fine crystals were removed; this effect was minimal in CHCl3.
(10) Reductions in dissolution rates in a continuous-flow system could best be interpreted by assuming that they reflected changes in the area of the hydrophilic solid exposed to the solvent.
(11) Applications from Serbia, which account for 10% of the total, stem mostly from the dissolution of former Yugoslavia: payment of army reservists, access to savings in present-day Bosnia and Herzegovina, pensions in Kosovo.
(12) The minimal advantage in rapidity of stone dissolution offered by tham E over tham is more than offset by the considerably increased potential for toxic side effects.
(13) The differences in the amounts of rapidly releasable calcium were attributed to different kinetics of calcium phosphate and calcium oxalate dissolution.
(14) The steps in the model are the drug elimination rate in the precornea and anterior chamber, the rate of drug dissolution, the rate of drug penetration into the cornea, and the rate of drug transport into the aqueous humor.
(15) Two commercial slow-release potassium chloride tablets, Slow-K and Addi-K have the characteristics of slow-release in the different dissolution conditions.
(16) Two consequences of these conditions are (1) patient classification into syndrome types (e.g., phonological dysgraphia, agrammatism, and so forth) can play no useful role in research concerned with issues about the structure of normal cognitive functioning or its dissolution under conditions of brain damage; and (2) only single-patient studies allow valid inferences about the structure of cognitive mechanisms from the analysis of impaired performance.
(17) Areas suggestive of cellular dissolution and disorganization were also reported in experimental parathyroids
(18) Speaking in Adelaide on Thursday as the government struggles to turn around its polling in South Australia before a possible double dissolution election, the prime minister went on the attack and said Labor was making major policy announcements on the fly.
(19) Although all three formulations were shown to have similar dissolution profiles, dissolution of chlorpropamide was pH-dependent in vitro.
(20) However, if solubility is considered as a function of pH at equilibrium, i.e., the final pH after the dissolution products have entered the solvent--a model more akin to the in vivo situation--hydroxyapatite is the conspicuously more soluble of the two minerals.