(a.) Destitute or deprived of inhabitants; deserted; uninhabited; hence, gloomy; as, a desolate isle; a desolate wilderness; a desolate house.
(a.) Laid waste; in a ruinous condition; neglected; destroyed; as, desolate altars.
(a.) Left alone; forsaken; lonely; comfortless.
(a.) Lost to shame; dissolute.
(a.) Destitute of; lacking in.
(v. t.) To make desolate; to leave alone; to deprive of inhabitants; as, the earth was nearly desolated by the flood.
(v. t.) To lay waste; to ruin; to ravage; as, a fire desolates a city.
Example Sentences:
(1) Downtown LA is improving, but for years it was a desolate hell zone of freeways, office blocks and closed stores.
(2) The coast here feels like an island, desolate and full of surprises.
(3) The Eritrean government requires every pupil to complete their final year of high school by serving in Sawa Military Camp, in the desolate, semi-desert region of eastern Eritrea .
(4) But for the next few hours, though, there's little to excite us: Joseph Weisenthal (@TheStalwart) The economic data calendar is a desolate wasteland of nothingness.
(5) When it is not clogged with weekend traffic, Container – the English word is used in Arabic – is a desolate spot: a lonely stretch of asphalt, four dingy tollbooth-like structures painted white and green, a few bored Israeli soldiers with automatic rifles.
(6) They are kept in a small pen behind the Lion's Den, a pub on a ranch in desolate countryside 75 miles south of Johannesburg.
(7) It was after the Indian wars of the 1870s that the indigenous tribes started to be consigned to reservations – on the worst, most desolate lands for grazing or growing crops.
(8) And, Jinkyo-En which was a desolate waste has come to an oasis in life for the Hansenites.
(9) The first time I saw the building - a stark, unapologetically angular silver bunker throwing back the heat of a rather desolate part of Berlin - I was content to register its disturbance without question, submitting to its strategies of oppression and disorientation as a child would.
(10) "Given the complexity of this crisis and the extent of the distress of our people from the north … we must together, I say together, clear the path ahead to free our country from these invaders, who only leave desolation, deprivation and pain in their wake."
(11) And it's Christmas bonanza time along the high streets of Britain, where Oxfam outlets and estate agents lie lonely amid empty sites and desolate closed doors.
(12) Australian visual effects wizard Dave Clayton has been nominated for his work on The Hobbit: The Desolation of Smaug.
(13) But, like many streets in New York City and in cities across the US, it is becoming increasingly desolate.
(14) Season two crafted complex characters racked with existential ambivalence – heroines marked for the abyss, fragile, flammable outcasts and desolate prodigies, all of whose private pain was as palpable as the crimson bloodbath head witch Evelyn Poole soaks in.
(15) Instead, they suggest expanding the scope of services in family planning clinics, out of an awareness that the continuing high prevalence of unintended childbearing, among the young and disadvantaged in particular, is part of a larger problem of living in a desolate social environment.
(16) "I watched this guy brushing off dirt from a skull in the most desolate landscape and right then I just knew," Rincón said of his first encounter with palaeontology.
(17) There was nothing to see for miles but sage-covered high desert, a landscape of stark beauty and eerie desolation.
(18) The contemporary state of the sub-discipline of endocrinology within the framework of internal medicine is generally considered rather desolate, but so far actual data were lacking.
(19) Howell said in July: "There are large uninhabited and desolate areas, certainly up in the north-east where there's plenty of room for fracking well away from anyone's residence where it can be conducted without any kind of threat to the rural environment."
(20) A subroutine called DESOL for the numerical solution of ordinary differential equations of the type arising in biological simulation problems is described.
Use
Definition:
(v. t.) The act of employing anything, or of applying it to one's service; the state of being so employed or applied; application; employment; conversion to some purpose; as, the use of a pen in writing; his machines are in general use.
(v. t.) Occasion or need to employ; necessity; as, to have no further use for a book.
(v. t.) Yielding of service; advantage derived; capability of being used; usefulness; utility.
(v. t.) Continued or repeated practice; customary employment; usage; custom; manner; habit.
(v. t.) Common occurrence; ordinary experience.
(v. t.) The special form of ritual adopted for use in any diocese; as, the Sarum, or Canterbury, use; the Hereford use; the York use; the Roman use; etc.
(v. t.) The premium paid for the possession and employment of borrowed money; interest; usury.
(v. t.) The benefit or profit of lands and tenements. Use imports a trust and confidence reposed in a man for the holding of lands. He to whose use or benefit the trust is intended shall enjoy the profits. An estate is granted and limited to A for the use of B.
(v. t.) A stab of iron welded to the side of a forging, as a shaft, near the end, and afterward drawn down, by hammering, so as to lengthen the forging.
(v. t.) To make use of; to convert to one's service; to avail one's self of; to employ; to put a purpose; as, to use a plow; to use a chair; to use time; to use flour for food; to use water for irrigation.
(v. t.) To behave toward; to act with regard to; to treat; as, to use a beast cruelly.
(v. t.) To practice customarily; to make a practice of; as, to use diligence in business.
(v. t.) To accustom; to habituate; to render familiar by practice; to inure; -- employed chiefly in the passive participle; as, men used to cold and hunger; soldiers used to hardships and danger.
(v. i.) To be wont or accustomed; to be in the habit or practice; as, he used to ride daily; -- now disused in the present tense, perhaps because of the similarity in sound, between "use to," and "used to."
(v. i.) To be accustomed to go; to frequent; to inhabit; to dwell; -- sometimes followed by of.
Example Sentences:
(1) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(2) These variants may serve as useful gene markers in alcohol research involving animal model studies with inbred strains in mice.
(3) Therefore, these findings may extend the use of platelets as neuronal models.
(4) All transplants were performed using standard techniques, the operation for the two groups differing only as described above.
(5) The resulting dose distribution is displayed using traditional 2-dimensional displays or as an isodose surface composited with underlying anatomy and the target volume.
(6) It was tested for recovery and separation from other selenium moieties present in urine using both in vivo-labeled rat urine and human urine spiked with unlabeled TMSe.
(7) A study revealed that the percentage of active sperm in semen 30 seconds after ejaculation was 10.3% when a nonoxynol 9 latex condom was used as opposed to 55.9% in a nonspermicidal condom.
(8) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(9) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(10) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
(11) Spectral analysis of spontaneous heart rate fluctuations, a powerful noninvasive tool for quantifying autonomic nervous system activity, was assessed in Xenopus Laevis, intact or spinalized, at different temperatures and by use of pharmacological tools.
(12) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(13) Questionnaires were used and the respondent self-designation method measured leadership.
(14) At 36 h postsurgery, RBCs were examined by 23Na-NMR by using dysprosium tripolyphosphate as a chemical shift reagent.
(15) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
(16) Use of the improved operative technique contributed to reduction in number of complications.
(17) Down and up regulation by peptides may be useful for treatment of cough and prevention of aspiration pneumonia.
(18) Our data suggest that a rational use of surveillance cultures and serological tests may aid in an earlier diagnosis of FI in BMT patients.
(19) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(20) Models able to describe the events of cellular growth and division and the dynamics of cell populations are useful for the understanding of functional control mechanisms and for the theoretical support for automated analysis of flow cytometric data and of cell volume distributions.