(v. i.) To be hopeless; to have no hope; to give up all hope or expectation; -- often with of.
(v. t.) To give up as beyond hope or expectation; to despair of.
(v. t.) To cause to despair.
(n.) Loss of hope; utter hopelessness; complete despondency.
(n.) That which is despaired of.
Example Sentences:
(1) Crushing their dream of denying healthcare to millions of people will put them on that road to despair.
(2) It was the ease with which minor debt could slide into a tangle of hunger and despair.
(3) The behavioural despair test is a good complement for screening except for drugs having a beta-agonist activity, it appears that this test is dependent on functional relationships between alpha 2 and serotonergic systems.
(4) It became his task to use his literary art in an opposite way to Hesse, even though he despaired of what literature might achieve or of the capacity of rich Europeans to change.
(5) He has his job to do and he has to do it the way he thinks best.” On Saturday night, in a sign of the growing concern at the top of the party about the affair, one shadow cabinet member told the Observer : “The issue is already echoing back at us on the doorsteps.” At all levels, there was despair that the furore had turned the spotlight on to Labour’s difficulties as a time when the party had hoped to take advantage of the Tories’ second byelection loss at the hands of Ukip.
(6) Many have been driven to a suicidal despair that only those devoid of human empathy can fail to understand.
(7) In recent weeks a number of suicides apparently linked to financial despair have hit the headlines.
(8) "You can get six, seven or eight calls a day, which would add to anyone's despair and depression.
(9) Thus in your own words you have said why it was utterly inappropriate for you to use the platform of a Pac hearing in this way.” He suggested that many professionals were “in despair at the lack of understanding and cheap haranguing which characterise your manner” after a series of hearings at which Hodge has led fierce interrogations of senior business figures and others.
(10) For Foos, arousal often competed with despair and sadness at what he witnessed.
(11) | Hugh Muir Read more Wherever Labour people gather to discuss how to break out of the vice tightening around the party, answers fail amid sighs of utter despair.
(12) The presumed interrelation between early rearing conditions and the neurobiological status of the infant that might lead to increased risk for despair is not understood.
(13) Erik Erikson used the film character of Dr. Borg from Wild Strawberries to flesh out his life cycle conception of ego integrity versus despair in old age.
(14) But the character – compounded of piercing sanity and existential despair, infinite hesitation and impulsive action, self-laceration and observant irony – is so multi-faceted, it is bound to coincide at some point with an actor’s particular gifts.
(15) He is an innately optimistic character as well as a clever one, and a man who needs to persuade his party not to despair.
(16) The present report deals with the effects of CBZ on two animal models of depression, namely the potentiation of amphetamine-induced anorexia, and the behavioral despair model.
(17) That is the secret of his repetitive name (like Nabokov's criminal hero in his novel Despair: Hermann Hermann, a misprint for Mr Man Mr Man).
(18) On the one hand, he genuinely sees himself as the great liberator of the poor, the man who wept at Britain’s modern-day penury on Glasgow’s Easterhouse estate; on the other, he is the champion of policies that have driven some of the poorest people in society into despair.
(19) Ovariectomy changed the swimming time course and increased the rhythmical index of depression without other serious disturbances of the behavioural "despair" test.
(20) I wanted to rediscover my joy in writing, I wanted to leave behind the heaviness and despair of Dead Europe .
Desperation
Definition:
(n.) The act of despairing or becoming desperate; a giving up of hope.
(n.) A state of despair, or utter hopeless; abandonment of hope; extreme recklessness; reckless fury.
Example Sentences:
(1) Michael Schumacher’s manager hopes F1 champion ‘will be here again one day’ Read more Last year, Red Bull were frustrated by Mercedes, Ferrari and Honda as they desperately looked for a new engine supplier.
(2) It is my desperate hope that we close out of town.” In the book, God publishes his own 'It Getteth Better' video and clarifies his original writings on homosexuality: I remember dictating these lines to Moses; and afterward looking up to find him staring at me in wide-eyed astonishment, and saying, "Thou do knowest that when the Israelites read this, they're going to lose their fucking shit, right?"
(3) While they may always be encumbered by censorship in a way that HBO is not, the success of darker storylines, antiheroes and the occasional snow zombie will not be lost in an entertainment industry desperate to maintain its share of the audience.
(4) Many hope this week's photocalls with the two men will be a recruiting aid and provide a desperately needed bounce in the polls.
(5) Hamilton said it was uncanny to find themselves in another desperate emergency situation almost exactly one year on.
(6) There are numerous other male protagonists out there in desperate need of a sex change.
(7) Frederick Juuko, a Ugandan law professor and critic of foreign influence in Ugandan politics, agrees that homosexuality is a pawn for many in times of desperation, including government.
(8) 9.23pm GMT Expect the reporters to get even more speculative and desperate from hereon in.
(9) He said: “Almost daily we hear from parents desperate to escape the single cramped room of a B&B or hostel that they find themselves struggling to raise their children in.
(10) The report's authors warns that to limit their spending councils will have "an incentive to discourage low-income families from living in the area" and that raises the possibility that councils will – like the ill-fated poll tax of the early 1990s – be left to chase desperately poor people through the courts for small amounts of unpaid tax.
(11) The local MP, Rory Stewart, a mover and shaker on the broadband project, told me that he was desperate to get telehealth into Cumbria, but regretfully felt that it was not immediately doable, because the local council and healthcare community did not yet have the necessary expertise.
(12) In desperation, I cancelled my contract with Sky and placed a new order with BT in February.
(13) When I heard it, I thought of Sherpa as a first name, like the Edmund in Edmund Hillary, rather than as a description, like the Desperate in Desperate Dan.
(14) Clark said he first met Brown in November 2004, just a few months before the general election when the party was in desperate need of funds.
(15) I tried desperately hard not to influence her, but I did steer her away from a baby that I've already bought her for her Christmas present.
(16) Patel once wrote: “At one end of this world, there is one woman who desperately needs a baby and cannot have her own child.
(17) Families like these are being abandoned to their fate and, as Steve Hynes of the Legal Action Group says: "These are often truly desperate people."
(18) Michael Holroyd, in his biography of George Bernard Shaw , gives an illuminating example of myopic hostility to Russia by the right even when we desperately needed allies.
(19) Police reinforcements are being sent to the embattled port of Calais in an attempt to prevent increasingly desperate attempts by migrants to gain access to the UK.
(20) "I desperately don't want this to suppress people's choice and freedom," says Stansfield.