(v. i.) To be hopeless; to have no hope; to give up all hope or expectation; -- often with of.
(v. t.) To give up as beyond hope or expectation; to despair of.
(v. t.) To cause to despair.
(n.) Loss of hope; utter hopelessness; complete despondency.
(n.) That which is despaired of.
Example Sentences:
(1) Crushing their dream of denying healthcare to millions of people will put them on that road to despair.
(2) It was the ease with which minor debt could slide into a tangle of hunger and despair.
(3) The behavioural despair test is a good complement for screening except for drugs having a beta-agonist activity, it appears that this test is dependent on functional relationships between alpha 2 and serotonergic systems.
(4) It became his task to use his literary art in an opposite way to Hesse, even though he despaired of what literature might achieve or of the capacity of rich Europeans to change.
(5) He has his job to do and he has to do it the way he thinks best.” On Saturday night, in a sign of the growing concern at the top of the party about the affair, one shadow cabinet member told the Observer : “The issue is already echoing back at us on the doorsteps.” At all levels, there was despair that the furore had turned the spotlight on to Labour’s difficulties as a time when the party had hoped to take advantage of the Tories’ second byelection loss at the hands of Ukip.
(6) Many have been driven to a suicidal despair that only those devoid of human empathy can fail to understand.
(7) In recent weeks a number of suicides apparently linked to financial despair have hit the headlines.
(8) "You can get six, seven or eight calls a day, which would add to anyone's despair and depression.
(9) Thus in your own words you have said why it was utterly inappropriate for you to use the platform of a Pac hearing in this way.” He suggested that many professionals were “in despair at the lack of understanding and cheap haranguing which characterise your manner” after a series of hearings at which Hodge has led fierce interrogations of senior business figures and others.
(10) For Foos, arousal often competed with despair and sadness at what he witnessed.
(11) | Hugh Muir Read more Wherever Labour people gather to discuss how to break out of the vice tightening around the party, answers fail amid sighs of utter despair.
(12) The presumed interrelation between early rearing conditions and the neurobiological status of the infant that might lead to increased risk for despair is not understood.
(13) Erik Erikson used the film character of Dr. Borg from Wild Strawberries to flesh out his life cycle conception of ego integrity versus despair in old age.
(14) But the character – compounded of piercing sanity and existential despair, infinite hesitation and impulsive action, self-laceration and observant irony – is so multi-faceted, it is bound to coincide at some point with an actor’s particular gifts.
(15) He is an innately optimistic character as well as a clever one, and a man who needs to persuade his party not to despair.
(16) The present report deals with the effects of CBZ on two animal models of depression, namely the potentiation of amphetamine-induced anorexia, and the behavioral despair model.
(17) That is the secret of his repetitive name (like Nabokov's criminal hero in his novel Despair: Hermann Hermann, a misprint for Mr Man Mr Man).
(18) On the one hand, he genuinely sees himself as the great liberator of the poor, the man who wept at Britain’s modern-day penury on Glasgow’s Easterhouse estate; on the other, he is the champion of policies that have driven some of the poorest people in society into despair.
(19) Ovariectomy changed the swimming time course and increased the rhythmical index of depression without other serious disturbances of the behavioural "despair" test.
(20) I wanted to rediscover my joy in writing, I wanted to leave behind the heaviness and despair of Dead Europe .
Disappointment
Definition:
(n.) The act of disappointing, or the state of being disappointed; defeat or failure of expectation or hope; miscarriage of design or plan; frustration.
(n.) That which disappoints.
Example Sentences:
(1) A spokesman for the Greens said that the party was “disappointed” with the decision and would be making representations to both the BBC and BBC Trust .
(2) Even today, our experience of the zoo is so often interrupted by disappointment and confusion.
(3) No one expected us to win either of these byelections, but we can’t ignore how disappointing these results are,” he said, referring also to last week’s Richmond Park byelection.
(4) "We were very disappointed when the DH decided to suspend printing Reduce the Risk, a vital resource in the prevention of cot death in the UK", said Francine Bates, chief executive of the Foundation for the Study of Infant Deaths, which helped produce the booklet.
(5) Results of medical therapy of reflux oesophagitis are disappointing, especially compared to the success obtained in peptic ulcer disease.
(6) Drugs used to promote food intake and weight gain, such as cyproheptadine, amitriptyline, clonidine and opiate antagonists, have provided disappointing results.
(7) I am pleased with that but disappointed with the result.
(8) How often do we use the term depressed to mean disappointed, mildly bummed out or sort of blue?
(9) I did not speak to Diego at the final whistle, losing so late in the game was too big a disappointment, especially when Romelu Lukaku was surrounded by three or four defenders and still scored.” That was something Martínez could agree with.
(10) For a long time the results were disappointing, and in a randomized study none of the therapeutic regimens prescribed could improve the patients' survival.
(11) Audiences were disappointed that the love scenes between Taylor and Burton that had been the talk of modern Rome were not repeated with so much passion in those of ancient Rome.
(12) Despite a glorious career, her Olympic history had been one of crushing disappointment.
(13) We are disappointed by the statement from Ecuador’s Foreign Minister that Ecuador has offered political asylum to Julian Assange.
(14) Here's Rob Booth talking to me from there: Updated at 6.31pm BST 6.14pm BST Disappointment at the Ecuadorian embassy Outside the Ecuador embassy in Knightsbridge a handful of Assange supporters greeted the decision with disappointment.
(15) While occult breast carcinoma was relatively common in our series (two of 17 patients), the ability to detect the tumor with mammography was disappointing (one of two patients).
(16) Diego Garcia guards its secrets even as the truth on CIA torture emerges Read more The long-awaited decision – expected to cause enormous disappointment – follows more than 40 years of campaigning, court cases and calls for the UK to right a wrong committed by Harold Wilson’s Labour government.
(17) They are also deeply disappointed in the lack of pressure exerted on Israel by the US.
(18) To improve the slightly disappointing voice rehabilitation results of the myotomized laryngectomees, a modified myotomy is proposed.
(19) An Artist of the Floating World won the Whitbread Book of the Year award and was nominated for the Booker prize for fiction; The Remains of the Day won the Booker; and When We Were Orphans, perceived by many reviewers as a disappointment, was nominated for both the Booker and the Whitbread.
(20) Jay is naturally disappointed, but is determined to get back playing for Southampton as soon as possible."