(v. i.) To be hopeless; to have no hope; to give up all hope or expectation; -- often with of.
(v. t.) To give up as beyond hope or expectation; to despair of.
(v. t.) To cause to despair.
(n.) Loss of hope; utter hopelessness; complete despondency.
(n.) That which is despaired of.
Example Sentences:
(1) Crushing their dream of denying healthcare to millions of people will put them on that road to despair.
(2) It was the ease with which minor debt could slide into a tangle of hunger and despair.
(3) The behavioural despair test is a good complement for screening except for drugs having a beta-agonist activity, it appears that this test is dependent on functional relationships between alpha 2 and serotonergic systems.
(4) It became his task to use his literary art in an opposite way to Hesse, even though he despaired of what literature might achieve or of the capacity of rich Europeans to change.
(5) He has his job to do and he has to do it the way he thinks best.” On Saturday night, in a sign of the growing concern at the top of the party about the affair, one shadow cabinet member told the Observer : “The issue is already echoing back at us on the doorsteps.” At all levels, there was despair that the furore had turned the spotlight on to Labour’s difficulties as a time when the party had hoped to take advantage of the Tories’ second byelection loss at the hands of Ukip.
(6) Many have been driven to a suicidal despair that only those devoid of human empathy can fail to understand.
(7) In recent weeks a number of suicides apparently linked to financial despair have hit the headlines.
(8) "You can get six, seven or eight calls a day, which would add to anyone's despair and depression.
(9) Thus in your own words you have said why it was utterly inappropriate for you to use the platform of a Pac hearing in this way.” He suggested that many professionals were “in despair at the lack of understanding and cheap haranguing which characterise your manner” after a series of hearings at which Hodge has led fierce interrogations of senior business figures and others.
(10) For Foos, arousal often competed with despair and sadness at what he witnessed.
(11) | Hugh Muir Read more Wherever Labour people gather to discuss how to break out of the vice tightening around the party, answers fail amid sighs of utter despair.
(12) The presumed interrelation between early rearing conditions and the neurobiological status of the infant that might lead to increased risk for despair is not understood.
(13) Erik Erikson used the film character of Dr. Borg from Wild Strawberries to flesh out his life cycle conception of ego integrity versus despair in old age.
(14) But the character – compounded of piercing sanity and existential despair, infinite hesitation and impulsive action, self-laceration and observant irony – is so multi-faceted, it is bound to coincide at some point with an actor’s particular gifts.
(15) He is an innately optimistic character as well as a clever one, and a man who needs to persuade his party not to despair.
(16) The present report deals with the effects of CBZ on two animal models of depression, namely the potentiation of amphetamine-induced anorexia, and the behavioral despair model.
(17) That is the secret of his repetitive name (like Nabokov's criminal hero in his novel Despair: Hermann Hermann, a misprint for Mr Man Mr Man).
(18) On the one hand, he genuinely sees himself as the great liberator of the poor, the man who wept at Britain’s modern-day penury on Glasgow’s Easterhouse estate; on the other, he is the champion of policies that have driven some of the poorest people in society into despair.
(19) Ovariectomy changed the swimming time course and increased the rhythmical index of depression without other serious disturbances of the behavioural "despair" test.
(20) I wanted to rediscover my joy in writing, I wanted to leave behind the heaviness and despair of Dead Europe .
Downcast
Definition:
(a.) Cast downward; directed to the ground, from bashfulness, modesty, dejection, or guilt.
(n.) Downcast or melancholy look.
(n.) A ventilating shaft down which the air passes in circulating through a mine.
Example Sentences:
(1) Green campaigners were rejoicing over the departure of the climate sceptic, while the National Farmers' Union was downcast at the exit of a cabinet minister who consistently stuck up for rural areas.
(2) In a concession message posted on Facebook, Hofer urged his supporters to not be downcast.
(3) But a downcast-looking Slim had managed to fulfil his promise to play live for fans.
(4) Moyles opened the show after the 6.30am news bulletin sounding downcast and launched into a long diatribe: "Do you know what, I wasn't going to come in today.
(5) It’s not Trump,” said one downcast store-owner recently.
(6) I was in captivity for three months and 20 days,” she says, eyes downcast.
(7) Look at him earlier this week, a downcast shadow at his own manifesto launch.
(8) It's mood may be as relentlessly downcast as ever, but Amnesiac sees Radiohead drawing a vast array of sounds and influences into their woeful world.
(9) Defoe looked furious with himself for missing that one and his manager simply downcast as he chewed his gum with increasingly manic intensity.
(10) No downcast beams to light up what was coming, breaking water, way off the coast.
(11) Cameron, who began his own ARV treatment 15 years ago, added: "While people are downcast after Marikana [mine massacre] and the slowing economy, I think Aids point to a public service achievement and shows we can do it if we put our minds to it."
(12) Any honest reporter will record the sheer weight of indifference, ignorance and cynicism that sends you away downcast by the distance between the disengaged and our little world of political obsessives.
(13) "It's disappointing, I wasn't expecting this," said a deeply downcast Poyet.
(14) A downcast Pep Guardiola later admitted his defence's frailties.
(15) Aristide's wife stood with her eyes downcast, twisting a handkerchief.
(16) And Swanny, who is not the most demonstrative person on the planet, had this really weird look on his face and said, ‘You can’t give the j’accuse speech and then sit down and do your correspondence.’ I was thinking, ‘Well, that must have hit a bit harder than it felt.’” Across the chamber, her political foes looked suddenly downcast.
(17) Outfoxed, out of luck and abandoned as never before, he looked tired and downcast.
(18) In short, Luhansk, under the LPR, has become a city of downcast faces.
(19) Eyes downcast, head bowed, hands clasped and legs crossed; Eddie, an introverted wheelchair user, had been in a dementia care home for a decade when he began sessions with arts charity Age Exchange .
(20) A downcast Sanchez spent most of the hearing with his head bowed, appearing to fight back tears while the judge explained the charge to him.