(v. i.) To be hopeless; to have no hope; to give up all hope or expectation; -- often with of.
(v. t.) To give up as beyond hope or expectation; to despair of.
(v. t.) To cause to despair.
(n.) Loss of hope; utter hopelessness; complete despondency.
(n.) That which is despaired of.
Example Sentences:
(1) Crushing their dream of denying healthcare to millions of people will put them on that road to despair.
(2) It was the ease with which minor debt could slide into a tangle of hunger and despair.
(3) The behavioural despair test is a good complement for screening except for drugs having a beta-agonist activity, it appears that this test is dependent on functional relationships between alpha 2 and serotonergic systems.
(4) It became his task to use his literary art in an opposite way to Hesse, even though he despaired of what literature might achieve or of the capacity of rich Europeans to change.
(5) He has his job to do and he has to do it the way he thinks best.” On Saturday night, in a sign of the growing concern at the top of the party about the affair, one shadow cabinet member told the Observer : “The issue is already echoing back at us on the doorsteps.” At all levels, there was despair that the furore had turned the spotlight on to Labour’s difficulties as a time when the party had hoped to take advantage of the Tories’ second byelection loss at the hands of Ukip.
(6) Many have been driven to a suicidal despair that only those devoid of human empathy can fail to understand.
(7) In recent weeks a number of suicides apparently linked to financial despair have hit the headlines.
(8) "You can get six, seven or eight calls a day, which would add to anyone's despair and depression.
(9) Thus in your own words you have said why it was utterly inappropriate for you to use the platform of a Pac hearing in this way.” He suggested that many professionals were “in despair at the lack of understanding and cheap haranguing which characterise your manner” after a series of hearings at which Hodge has led fierce interrogations of senior business figures and others.
(10) For Foos, arousal often competed with despair and sadness at what he witnessed.
(11) | Hugh Muir Read more Wherever Labour people gather to discuss how to break out of the vice tightening around the party, answers fail amid sighs of utter despair.
(12) The presumed interrelation between early rearing conditions and the neurobiological status of the infant that might lead to increased risk for despair is not understood.
(13) Erik Erikson used the film character of Dr. Borg from Wild Strawberries to flesh out his life cycle conception of ego integrity versus despair in old age.
(14) But the character – compounded of piercing sanity and existential despair, infinite hesitation and impulsive action, self-laceration and observant irony – is so multi-faceted, it is bound to coincide at some point with an actor’s particular gifts.
(15) He is an innately optimistic character as well as a clever one, and a man who needs to persuade his party not to despair.
(16) The present report deals with the effects of CBZ on two animal models of depression, namely the potentiation of amphetamine-induced anorexia, and the behavioral despair model.
(17) That is the secret of his repetitive name (like Nabokov's criminal hero in his novel Despair: Hermann Hermann, a misprint for Mr Man Mr Man).
(18) On the one hand, he genuinely sees himself as the great liberator of the poor, the man who wept at Britain’s modern-day penury on Glasgow’s Easterhouse estate; on the other, he is the champion of policies that have driven some of the poorest people in society into despair.
(19) Ovariectomy changed the swimming time course and increased the rhythmical index of depression without other serious disturbances of the behavioural "despair" test.
(20) I wanted to rediscover my joy in writing, I wanted to leave behind the heaviness and despair of Dead Europe .
Hopeless
Definition:
(a.) Destitute of hope; having no expectation of good; despairing.
(a.) Giving no ground of hope; promising nothing desirable; desperate; as, a hopeless cause.
(a.) Unhoped for; despaired of.
Example Sentences:
(1) Its experiments are so hopelessly flawed that the results are meaningless."
(2) They were preceded by the publication of The Success and Failure of Picasso (1965) and Art and Revolution: Ernst Neizvestny and the Role of the Artist in the USSR (1969); in one, he made a hopeless mess of Picasso’s later career, though he was not alone in this; in the other, he elevated a brave dissident artist beyond his talents.
(3) Rather than ruthlessly efficient, I have found them sweet and a bit hopeless."
(4) Alcohol and drugs are influential in providing a feeling of hopelessness by their toxic effects, by disruption of interpersonal relationships and social supports, and, possibly, by manipulating neurotransmitters responsible for mood and judgment.
(5) The authors document the first 19 months of a service dedicated to the care of hopelessly ill patients in a teaching hospital.
(6) "); hopeless self-pity ("Nobody said anything to me about Billy ... all day long") and rage ("You want to put a bench in the park in Billy's name?
(7) Winston Churchill, when he was offered the role of minister of the local government board in 1906, commented: "There is no place more laborious, more anxious, more thankless, more cloaked with petty and even squalid detail, more full of hopeless and insoluble difficulties."
(8) It’s all very well for Hopeless to make fun of me saying Brexit means Brexit,” said Hapless, haplessly.
(9) Meanwhile, the dance music that sells in any quantity is just hopeless.
(10) Both depression and hopelessness were sensitive to changes in suicide risk during the one-month follow-up.
(11) Many aspects of the theory's descriptive claims about depressive thinking have been substantiated empirically, including (a) increased negativity of cognitions about the self, (b) increased hopelessness, (c) specificity of themes of loss to depressive syndromes rather than psychopathology in general, and (d) mood-congruent recall.
(12) In addition, the paper presents the author's experience with human vitreous transplantation by the 'open sky' transcorneal technique for otherwise hopeless vitreous opacities.
(13) The relationship between depression and suicide disappears when hopelessness is taken into account.
(14) The performance of controls and DST escapers was related to depth of semantic processing, whereas performance of DST suppressors varied inversely with degree of felt hopelessness.
(15) The question of vulnerability to DSH is discussed as well as the possibility of using measures of hopelessness and intropunitive hostility to identify those at greater risk of repetition.
(16) But the Labour leader has only himself to blame because of his hopelessly woolly response to a question on this in his BBC interview on Monday.
(17) "It was a certain kind of titillation the shop offered," the critic Matthew Collings has written, "sexual but also hopeless, destructive, foolish, funny, sad."
(18) Shinji Kagawa could not make any real difference and Marouane Fellaini continues to look hopelessly out of his depth.
(19) Anhedonia, diurnal variation, hopelessness, psychomotor retardation, and delusions increased with age; depressed appearance, low self-esteem, and somatic complaints decreased with age.
(20) Four cases received no treatment but were recalled, and twelve perforations showed a size and location hopeless for repair; the teeth were therefore extracted.