(v. i.) To be hopeless; to have no hope; to give up all hope or expectation; -- often with of.
(v. t.) To give up as beyond hope or expectation; to despair of.
(v. t.) To cause to despair.
(n.) Loss of hope; utter hopelessness; complete despondency.
(n.) That which is despaired of.
Example Sentences:
(1) Crushing their dream of denying healthcare to millions of people will put them on that road to despair.
(2) It was the ease with which minor debt could slide into a tangle of hunger and despair.
(3) The behavioural despair test is a good complement for screening except for drugs having a beta-agonist activity, it appears that this test is dependent on functional relationships between alpha 2 and serotonergic systems.
(4) It became his task to use his literary art in an opposite way to Hesse, even though he despaired of what literature might achieve or of the capacity of rich Europeans to change.
(5) He has his job to do and he has to do it the way he thinks best.” On Saturday night, in a sign of the growing concern at the top of the party about the affair, one shadow cabinet member told the Observer : “The issue is already echoing back at us on the doorsteps.” At all levels, there was despair that the furore had turned the spotlight on to Labour’s difficulties as a time when the party had hoped to take advantage of the Tories’ second byelection loss at the hands of Ukip.
(6) Many have been driven to a suicidal despair that only those devoid of human empathy can fail to understand.
(7) In recent weeks a number of suicides apparently linked to financial despair have hit the headlines.
(8) "You can get six, seven or eight calls a day, which would add to anyone's despair and depression.
(9) Thus in your own words you have said why it was utterly inappropriate for you to use the platform of a Pac hearing in this way.” He suggested that many professionals were “in despair at the lack of understanding and cheap haranguing which characterise your manner” after a series of hearings at which Hodge has led fierce interrogations of senior business figures and others.
(10) For Foos, arousal often competed with despair and sadness at what he witnessed.
(11) | Hugh Muir Read more Wherever Labour people gather to discuss how to break out of the vice tightening around the party, answers fail amid sighs of utter despair.
(12) The presumed interrelation between early rearing conditions and the neurobiological status of the infant that might lead to increased risk for despair is not understood.
(13) Erik Erikson used the film character of Dr. Borg from Wild Strawberries to flesh out his life cycle conception of ego integrity versus despair in old age.
(14) But the character – compounded of piercing sanity and existential despair, infinite hesitation and impulsive action, self-laceration and observant irony – is so multi-faceted, it is bound to coincide at some point with an actor’s particular gifts.
(15) He is an innately optimistic character as well as a clever one, and a man who needs to persuade his party not to despair.
(16) The present report deals with the effects of CBZ on two animal models of depression, namely the potentiation of amphetamine-induced anorexia, and the behavioral despair model.
(17) That is the secret of his repetitive name (like Nabokov's criminal hero in his novel Despair: Hermann Hermann, a misprint for Mr Man Mr Man).
(18) On the one hand, he genuinely sees himself as the great liberator of the poor, the man who wept at Britain’s modern-day penury on Glasgow’s Easterhouse estate; on the other, he is the champion of policies that have driven some of the poorest people in society into despair.
(19) Ovariectomy changed the swimming time course and increased the rhythmical index of depression without other serious disturbances of the behavioural "despair" test.
(20) I wanted to rediscover my joy in writing, I wanted to leave behind the heaviness and despair of Dead Europe .
Sorrow
Definition:
(n.) The uneasiness or pain of mind which is produced by the loss of any good, real or supposed, or by diseappointment in the expectation of good; grief at having suffered or occasioned evil; regret; unhappiness; sadness.
(n.) To feel pain of mind in consequence of evil experienced, feared, or done; to grieve; to be sad; to be sorry.
Example Sentences:
(1) It came in a mix of joy and sorrow and brilliance under pressure, with one of the most remarkable things you will ever see on a basketball court in the biggest moment.
(2) Troh, a 54-year-old nursing assistant, issued a statement on Wednesday that said: “I trust a thorough examination will take place regarding all aspects of his care … I am now dealing with the sorrow and anger that his son was not able to see him before he died.” That appeared to be a reference to frustration at the hospital’s initial failure to diagnose him correctly, and a delay of several days before they treated him with experimental drugs.
(3) Goodman deceived us all, the witnesses sorrowfully admitted.
(4) Photograph: AP This is the moment of our deepest sorrow.
(5) Separately, in a Question Time-style debate at the Radio Festival today, Ofcom executive Stewart Purvis said he reacted "more in sorrow than anger" at yesterday's stinging attack on the regulator by former GMG Radio chief executive John Myers .
(6) 'This is not the justice we seek': sorrow in Baltimore as grief turns into riots Read more The city has improved significantly in recent years – crime dropped, the economy improved, the population stopped declining for the first time in 60 years – but you couldn’t see Baltimore’s newfound prosperity in Freddie Gray’s backyard, or in the gardens nearby.
(7) But at this moment of the final parting, my heart is heavy with sorrow and grief.” On death: “There is an end to everything and I want mine to come as quickly and painlessly as possible, not with me incapacitated, half in coma in bed and with a tube going into my nostrils and down to my stomach.” “Even from my sickbed, even if you are going to lower me to the grave and I feel that something is going wrong, I will get up.
(8) Time to listen to ‘World in Motion’ on loop while drowning a million sweet sorrows.
(9) Shara Proctor, who might have had hopes of gold while Okagbare busied herself with the 200m, managed only two steps of a run-up before clutching at her left thigh and leaving the arena with her hoodie pulled sorrowfully around her face.
(10) Prayer has comforted us in sorrow, and will help strengthen us for the journey ahead.
(11) "Would all these girls," he asks, with a sorrow that defies any glib, one-should-be-so-lucky retort, "be fucking me if they weren't getting paid?"
(12) I have immense sorrow over the loss of that child but I also have immense joy when I think of her.
(13) More than a dozen times in his presidency, Barack Obama has appeared before television cameras and issued statements to express sorrow at a mass shooting event in America.
(14) The emotion called chronic sorrow, introduced in 1962 by Olshansky, has had limited exposure in the literature.
(15) Yet the Brazilians who were photographed unleashing their sorrow on a cloudy, darkening evening, in scenes of anguish from Estádio Mineirão to Copacabana beach, were not mourning a massacre, atrocity or anything else that might seem to justify such infinite sadness.
(16) This too, I recognise, is another coping strategy, a way to get through what could be a sorrowful few years or even decades ahead.
(17) Every day I spend in sorrow, thinking about my family and how to reach the UK.” Intelligent, and very motivated, he is particularly frustrated at not being to able to study; eventually he hopes to become a doctor.
(18) For my own part, I would like to express sorrow and regret to those most distressed by the actions of my predecessor.
(19) American viewers mourning the death of Dan Stevens' character Matthew Crawley at the end of the show's Christmas special will be able to drown their sorrows with Downton wine, wear Downton jewellery and grow Downton roses, as part of a merchandising push aimed at capitalising on the drama's phenomenal global success.
(20) The concert has been long prepared, Josh and his friend Ahmed from the perilous estates nearby laying tracks to "Jessie Wright" and another song for Agnes – "a tribute to a girl got shot in Hoxton", Josh says, with apparent nonchalance, but a stab of sorrowful anger in his eye.