(1) It appears that irrespective of the elucidation of the nature of the putative aetiological factor (presumed to be viral) in MS, the arrest and reversal of T cell-related events within the CNS in this devastating condition represent feasible goals and should remain a major target for some time to come.
(2) Samaras said: A "Grexit", as it is called, would be devastating for Greece and detrimental to Europe.
(3) While winds gusting to 170mph caused significant damage, the devastation in areas such as Tacloban – where scenes are reminiscent of the 2004 Indian ocean tsunami – was principally the work of the 6-metre-high storm surge, which carried away even the concrete buildings in which many people sought shelter.
(4) The Financial Services Authority is meant to be the City's watchdog but "devastating" internal documents reveal it has secretly co-ordinated high-level lobbying strategies with the industry it is supposed to police.
(5) The government acknowledged it had been overwhelmed by the devastation from the deadliest quake in Nepal in over 80 years.
(6) Mark Rasch, a cyber crime expert quoted by the FT, meanwhile said recent events have been “a serious and devastating attack to [Sony’s] reputation and image”, and his opinion is played out by a new YouGov poll into the public perception of Sony’s brand.
(7) "When people don't feel they have a reason to stay out of trouble, the consequences for communities can be devastating – as we saw last August," said Darra Singh, chair of the panel.
(8) Newcastle United are “devastated” by their relegation from the Premier League, according to the club’s managing director Lee Charnley.
(9) In order to reduce the devasting effects of enteric diseases among children born to mothers in tropical countries of Africa and Asia, it is imperative that all health workers understand the cultural and social perceptions of their clients towards the disease in question.
(10) All the personality, dignity and humanity of a person are devastated by this torture.
(11) Age UK believes McDonald's human rights have been breached and that there could be "extremely adverse and devastating consequences for many thousands of older people if other councils take similar decisions to save money".
(12) And then, as the Guardian revealed at the weekend, there is the potentially devastating effect of the boundary changes, which can’t really be brought in before an early election but will radically tilt the field by 2020.
(13) He said: "[That] could be devastating for the renewables industry.
(14) To say that the loss of BB King is devastating to the blues community is an understatement.
(15) 'Devastated' Peter Greste calls on Egypt's president to pardon trio Read more “It’s ironic that the conviction was for tarnishing Egypt’s reputation when ... this [case] is what’s tarnished Egypt’s image,” Clooney told BBC News.
(16) The report, extracts of which were published by the investigative news website Exaro , is said to include “devastating detail” of the corporation’s “sheer scale of awareness” of the late star’s activities.
(17) Although anterior and posterior traumatic displacement of cervical vertebrae are commonly noted, and the devastating neurological deficits associated with these injuries have been amply defined, lateral displacement with fractures has been rarely recognized, and the clinical significance of this injury has been overlooked.
(18) Bernard Hogan-Howe, the Met commissioner, said a report revealing the undercover officers had spied on the family of murdered teenager Stephen Lawrence was “devastating” for Scotland Yard and “one of the worst days that I have seen as a police officer”.
(19) The case for halting British arms sales to Saudi Arabia has been evident, not only on moral grounds, since civilians started dying in the conflict devastating Yemen.
(20) Devastating neurologic complications can be avoided or alleviated in a great proportion of patients undergoing radiation therapy for cerebral metastases and spinal cord compression.
Heartbroken
Definition:
(a.) Overcome by crushing sorrow; deeply grieved.
Example Sentences:
(1) But I've never been in a relationship and been heartbroken.
(2) Yu Hongchen, the vice dean of China’s football management centre, said Team China players had been left “heartbroken” by the defeat to Syria.
(3) Cheryl Boone Isaacs, president of the Academy of Motion Picture Arts and Sciences (AMPAS), which organises the Oscars, has said she’s “heartbroken” by the lack of diversity and that AMPAS will be taking “dramatic steps” to adjust the balance of its membership to include more black and ethnic minority film-makers.
(4) She said: "We are absolutely heartbroken," and blamed his illness on a lifetime of cigarette smoking.
(5) Kaplinsky, the TV presenter who won Strictly Come Dancing in 2004, was said to have been “heartbroken” when private details of her wedding and honeymoon were published.
(6) "In the conclusion of the tragedy by Chekohov, everyone is disappointed, disillusioned, embittered, heartbroken, but alive."
(7) Without sounding like a cynical heartbroken niece, I welcome the Sports Charter and above all hope it will finally bring tolerance and change in one of the most loved games in the world.
(8) At this point in time our family is heartbroken, not able to grieve; his body is still in the mortuary all alone.
(9) Heartbroken, Paul refused to leave the Portland Place apartment, the place where his daughter passed away.
(10) Minister Stan Smith said members of the Cornerstone Community Church congregation were offering to mourn with people who were heartbroken by the news of Henning's death.
(11) As someone who had a chance to talk to him in the past, I really feel heartbroken to see how he has been treated,” said Patrick Poon, a Hong Kong-based Amnesty International activist.
(12) Yvette van Schalkwyk, a social worker and probation officer assigned to Pistorius after he shot dead his girlfriend, testified that he was sincerely heartbroken and sorry for what Reeva Steenkamp's parents were going through.
(13) Iwas heartbroken to read about the impact of child sexual abuse on the former footballers Andy Woodward , Steve Walters and Paul Stewart .
(14) Meanwhile , the company's founder Guy Laliberté – the stilt walker who in 2009 became a billionaire space tourist – has said he is "heartbroken" by the traumatic accident.
(15) "Twenty heartbroken families lost a child in the Sandy Hook school shooting," Green says in the video.
(16) He said that Reed remained "heartbroken" by the incident, in which he lost friends and co-workers.
(17) Fastest in tournament history Facebook Twitter Pinterest Brazil fans were heartbroken after the 7-1 defeat by Germany
(18) "We’re heartbroken that something like this might have happened again," the president said.
(19) The German media have been more awed than heartbroken by the spectacular match between Liverpool and Dortmund: “4:3!
(20) He upset already-heartbroken volunteers and activists further with this statement.