(1) It appears that irrespective of the elucidation of the nature of the putative aetiological factor (presumed to be viral) in MS, the arrest and reversal of T cell-related events within the CNS in this devastating condition represent feasible goals and should remain a major target for some time to come.
(2) Samaras said: A "Grexit", as it is called, would be devastating for Greece and detrimental to Europe.
(3) While winds gusting to 170mph caused significant damage, the devastation in areas such as Tacloban – where scenes are reminiscent of the 2004 Indian ocean tsunami – was principally the work of the 6-metre-high storm surge, which carried away even the concrete buildings in which many people sought shelter.
(4) The Financial Services Authority is meant to be the City's watchdog but "devastating" internal documents reveal it has secretly co-ordinated high-level lobbying strategies with the industry it is supposed to police.
(5) The government acknowledged it had been overwhelmed by the devastation from the deadliest quake in Nepal in over 80 years.
(6) Mark Rasch, a cyber crime expert quoted by the FT, meanwhile said recent events have been “a serious and devastating attack to [Sony’s] reputation and image”, and his opinion is played out by a new YouGov poll into the public perception of Sony’s brand.
(7) "When people don't feel they have a reason to stay out of trouble, the consequences for communities can be devastating – as we saw last August," said Darra Singh, chair of the panel.
(8) Newcastle United are “devastated” by their relegation from the Premier League, according to the club’s managing director Lee Charnley.
(9) In order to reduce the devasting effects of enteric diseases among children born to mothers in tropical countries of Africa and Asia, it is imperative that all health workers understand the cultural and social perceptions of their clients towards the disease in question.
(10) All the personality, dignity and humanity of a person are devastated by this torture.
(11) Age UK believes McDonald's human rights have been breached and that there could be "extremely adverse and devastating consequences for many thousands of older people if other councils take similar decisions to save money".
(12) And then, as the Guardian revealed at the weekend, there is the potentially devastating effect of the boundary changes, which can’t really be brought in before an early election but will radically tilt the field by 2020.
(13) He said: "[That] could be devastating for the renewables industry.
(14) To say that the loss of BB King is devastating to the blues community is an understatement.
(15) 'Devastated' Peter Greste calls on Egypt's president to pardon trio Read more “It’s ironic that the conviction was for tarnishing Egypt’s reputation when ... this [case] is what’s tarnished Egypt’s image,” Clooney told BBC News.
(16) The report, extracts of which were published by the investigative news website Exaro , is said to include “devastating detail” of the corporation’s “sheer scale of awareness” of the late star’s activities.
(17) Although anterior and posterior traumatic displacement of cervical vertebrae are commonly noted, and the devastating neurological deficits associated with these injuries have been amply defined, lateral displacement with fractures has been rarely recognized, and the clinical significance of this injury has been overlooked.
(18) Bernard Hogan-Howe, the Met commissioner, said a report revealing the undercover officers had spied on the family of murdered teenager Stephen Lawrence was “devastating” for Scotland Yard and “one of the worst days that I have seen as a police officer”.
(19) The case for halting British arms sales to Saudi Arabia has been evident, not only on moral grounds, since civilians started dying in the conflict devastating Yemen.
(20) Devastating neurologic complications can be avoided or alleviated in a great proportion of patients undergoing radiation therapy for cerebral metastases and spinal cord compression.
Upset
Definition:
(v. t.) To set up; to put upright.
(v. t.) To thicken and shorten, as a heated piece of iron, by hammering on the end.
(v. t.) To shorten (a tire) in the process of resetting, originally by cutting it and hammering on the ends.
(v. t.) To overturn, overthrow, or overset; as, to upset a carriage; to upset an argument.
(v. t.) To disturb the self-possession of; to disorder the nerves of; to make ill; as, the fright upset her.
(v. i.) To become upset.
(a.) Set up; fixed; determined; -- used chiefly or only in the phrase upset price; that is, the price fixed upon as the minimum for property offered in a public sale, or, in an auction, the price at which property is set up or started by the auctioneer, and the lowest price at which it will be sold.
(n.) The act of upsetting, or the state of being upset; an overturn; as, the wagon had an upset.
Example Sentences:
(1) A series of hierarchical multiple regressions revealed the effects of Surgency, Agreeableness, Conscientiousness, Emotional Stability, and Intellect on evoking upset in spouses through condescension (e.g., treating spouse as stupid or inferior), possessiveness (demanding too much time and attention), abuse (slapping spouse), unfaithfulness (having sex with others), inconsiderateness (leaving toilet seat up), moodiness (crying a lot), alcohol abuse (drinking too much alcohol), emotional constriction (hiding emotions to act tough), and self-centeredness (acting selfishly).
(2) Mean run time and total ST time were faster with CE (by 1.4 and 1.2 min) although not significantly different (P less than 0.06 and P less than 0.10) from P. Subjects reported no significant difference in nausea, fullness, or stomach upset with CE compared to P. General physiological responses were similar for each drink during 2 h of multi-modal exercise in the heat; however, blood glucose, carbohydrate utilization, and exercise intensity at the end of a ST may be increased with CE fluid replacement.
(3) Treatment is therefore often palliative, and endoscopic modalities cause considerably less general upset to the patient than surgery, radiotherapy or chemotherapy.
(4) We interpreted these results within an attributional framework that emphasizes the salience of upsetting events within a social network.
(5) She stayed calm during the upsetting search that led to Cynthia, who turned out to be flaky, chain-smoking and white (played by Brenda Blethyn).
(6) Trump might say that is what he wants to happen but for us, that’s deeply upsetting,” says Moore, who sits on the board of the Center Against Sexual and Family Violence and expects the case to have a chilling effect on reports of abuse.
(7) We’re all very upset right now,” said Daniel Ray, 24, in his third year of the divinity master’s degree program.
(8) Al-Jazeera's coverage has also upset the authorities.
(9) Our observations lead us to think that effectively, an event during which an important emotional state is induced, by upsetting the immune equilibrium, could more predispose a child (in this case the first born) to the action of pathogens.
(10) The interview was a friendly, intense discussion about upsetting situations the subject faced.
(11) A fired-up Lleyton Hewitt just fell short in his bid to steer Australia to an upset victory in their Davis Cup doubles showdown with the United States.
(12) She [Plath] was very worried about it because she thought it was going to upset her mother.
(13) Diagnostic characteristics of RSDS are: spontaneous burning pain, hyperalgesia, vasomotor disturbances, exacerbations by emotional upset, occurrence either spontaneously or after minor injury, occasional spontaneous resolution, extension to other body parts, and relief by sympathetic denervation.
(14) Plenty of people felt embarrassed, upset, outraged or betrayed by the Goncourts' record of things they had said or had said about them.
(15) The territory is actualy reached by deep demographic and social upsettings and chemiotherapy used alone is not enough efficient to obtain a definitive decrease of the endemy or even to avoid, for a long time, a new increase.
(16) The amount he is being paid for three short columns a week would “only get you sandal wearers all upset” if revealed, he says.
(17) The CPS doesn't just have to consider the public interest in prosecuting individual cases, but also the more general public interest in being able to say potentially upsetting things without fear of prosecution.
(18) As with other selective serotonin reuptake inhibitors (SSRIs), the most common side effect is gastrointestinal upset, especially nausea.
(19) It's possible that it upsets her to think about the past, or perhaps, these days, she saves her animation for the times when she is holding a microphone and standing in front of a swollen, angry crowd.
(20) The conclusion from this, the first reported series on adjuvant Tamoxifen therapy for MBC, is that significant improvement in disease-free survival can be achieved with minimal upset to the patients.