(a.) Hard to do or to make; beset with difficulty; attended with labor, trouble, or pains; not easy; arduous.
(a.) Hard to manage or to please; not easily wrought upon; austere; stubborn; as, a difficult person.
(v. t.) To render difficult; to impede; to perplex.
Example Sentences:
(1) Virtually every developed country has some form of property tax, so the idea that valuing residential property is uniquely difficult, or that it would be widely evaded, is nonsense.
(2) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(3) In practice, however, the necessary dosage is difficult to predict.
(4) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
(5) By drawing from the pathophysiology, this article discusses a multidimensional approach to the treatment of these difficult patients.
(6) Past imaging techniques shown in the courtroom have made the conventional rules of evidence more difficult because of the different informational content and format required for presentation of these data.
(7) The way we are going to pay for that is by making the rules the same for people who go into care homes as for people who get care at their home, and by means-testing the winter fuel payment, which currently isn’t.” Hunt said the plan showed the Conservatives were capable of making difficult choices.
(8) In many cases, physicians seek to protect themselves from involvement with these difficult, highly anxious patients by making a referral to a psychiatrist.
(9) The diagnosis of variant- or Prizmetal-angina is difficult because if insufficient specificity of the tests.
(10) The detection of these antibodies is difficult owing to the lack of standardization and of specificity of the laboratory tests.
(11) It was so difficult to keep a straight face when I was filming a sauna scene with Roy Barraclough, who played the mayor of Blackpool.
(12) That is, he believes, to look at massively difficult, interlocking problems through too narrow a lens.
(13) Conversion of the active-site thiol to thiocyanate makes it more difficult to inactivate the enzyme by treatment with Cd2+.
(14) If they end up going to another club that is difficult to take.
(15) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(16) The most difficult thing I've dealt with at work is ... the terminal illness of a valued colleague.
(17) In that respect, it's difficult to see Allen's anthem as little more than same old same old, and it's probably why I ultimately feel she misses the mark.
(18) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(19) Extrapolation of gestational age from early crown-rump lengths (CRLs) has been difficult because previously established tables of CRL versus gestational age have contained few measurements at less than seven to eight weeks from the first day of the last menses.
(20) Companies had made investments in certain energy sources, the president said, so change could be “uncomfortable and difficult”.
Troublesome
Definition:
(a.) Giving trouble or anxiety; vexatious; burdensome; wearisome.
Example Sentences:
(1) Second, the nurse must be aware of the wide range of feeling and attitudes on specific sexual issues that have proved troublesome to our society.
(2) Both drugs were relatively well tolerated, but trimipramine had a sedative effect which proved troublesome in some patients.
(3) Initial experience with the use of bromocriptine in 24 patients with troublesome micturition symptoms associated with an unstable bladder is described.
(4) Patients had troublesome symptoms uncontrolled by high doses of inhaled corticosteroids (mean 1450 micrograms).
(5) The EU report said that the MIT, Turkey’s intelligence service, had begun compiling lists of “troublesome individuals” years ago.
(6) She does talk openly and movingly about Barbara, though, whose rebelliousness became so troublesome for her parents that she was placed in various institutions during her teens.
(7) To try to determine the relative contributions of sensory and motor neuropathy in this troublesome complication, anorectal function was examined in 10 male diabetic patients with early faecal incontinence (mucus leakage or faecal staining without the need to wear a pad), 10 asymptomatic male diabetic patients, and 10 normal control subjects.
(8) The diabetics complained more often of fear and anxiety about future, fluctuations in mood and were finding their daily life more troublesome.
(9) Troublesome unwanted effects occurred in six patients.
(10) No one would deny that Thomas drank too much or that he could be a troublesome drunk.
(11) Since then, researchers have studied the problem of troublesome behavior in demented patients and the burden that this creates for relatives nursing them.
(12) Debate over the current sources of financing reveals several troublesome issues: the presence of residents allegedly decreases the productivity of professionals and leads to overusage of ancillary services, proposed methods to pay for faculty salaries and services have created confusion and concern, and the financing of ambulatory-care training has been insufficient and poorly coordinated.
(13) RBS starts charging financial customers to park their cash Read more The disposal of W&G is proving troublesome and expensive for RBS, which stunned the City last month by admitting it was abandoning its attempt to float the business on the stock market.
(14) Conversely, having no credit history can be just as troublesome as having a poor rating: without a history of spending and repayments, a bank may be less willing to loan you money.
(15) His subcorneal pustular dermatosis subsequently flared and was troublesome for 2 years until he was commenced on PUVA, with excellent response.
(16) Nevertheless their insertion is sometime troublesome and a superficial knowledge of the technical problems may lead to complete and disappointing failures.
(17) For instance; hesitant to go to a hot spring, or on a trip with friends (76%), hesitant to go to a clinic or a hospital for physical check-ups and common illness (74%), troublesome to wear special underwear (69%), inconvenient because ordinary clothes cannot be worn (56%), distressed when viewing own body (52%), unable to dress in thin clothes in hot summer season (50%), imbalance of the breasts (49%), inconvenient to participate in sports (47%).
(18) Baseline wander and muscle artifact are particularly troublesome sources of interference.
(19) Cardiovascular instability and eradication of analgesia have been troublesome, especially with the use of naloxone.
(20) The radical mastoid cavity can be troublesome and odoriferous, may require frequent visits to an otologist, and may interfere with swimming and showering.