(1) However, no evidence could be discerned to support its validity as a measure of a patient's treatment outcome.
(2) Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.
(3) This was apparent by standard flux techniques only in low (65 mM) Na solutions, but was readily discernible in normal Na (125 mM) with the "lanthanum-residual" technique.
(4) By this method two types of granules have been discerned according to their different contrasts.
(5) Several stages in its histogenesis may be discerned: I. focal necroses of hepatic cells associated with their invasion with lister Listeria; 2. appearance of cellular elements around the foci of necroses with subsequent formation of granulemas consisting mainly of leucocytes and lymphoid cells; 3. development of necrobiotic changes in the central areas of granulemas with concomitance of exudative processes; 4. organization of necrotic foci with subsequent scarring.
(6) Significant increment in lipid peroxidation was discernible in brain, liver and muscle.
(7) While there's no discernible forró influence in the dreamy 80s indie-guitar music of Fortaleza's Cidadão Instigado, they do take influence from popular local style brega, a 1970s and 80s Brazilian romantic pop music.
(8) Furthermore, individual AgNOR dots were much more readily discerned in cell imprints than in sections, and this appears to be the method of choice if pathologists wish to at least approach absolute rather than relative AgNOR counts.
(9) In order to assess the sensitivity of these techniques, and to discern minimal criteria for their conduct, a survey of 113 human lymphocyte cytogenetic surveillance studies conducted between 1965 and 1984 has been undertaken.
(10) Changes in the secretory process were discernible as of day 1 in all three tumors, with a dramatic reduction of exocytosis and intracellular accumulation of PRL-immunoreactive granules.
(11) The advent of cyclosporine A provides the dermatologist with a new therapeutic strategem in the management of psoriasis, although the long-term safety of such interventional therapy remains to be discerned.
(12) Histologically, no discernible changes in the hair cells or sensory hairs were found with a scanning electron microscope at about 6 hours after 10 krad irradiation, while with a transmission electron microscope, the outer hair cells in the basal coil of the cochlea were found to be mostly destroyed.
(13) However, by phase microscopy, no changes are discernible within the first 12-18 h. Since the primary NGF receptor appears to be a membrane receptor, it seemed likely that some of the initial responses to the factor may be surface related.
(14) Whereas no discernible differences on survival were documented on a long-term basis, when patient who ultimately recurred in each group were compared, a substantial and statistically significant prolongation of the free-of-disease interval from surgery to recurrence and of survival from recurrence to death are revealed.
(15) The results suggest that TGF-beta 1 has powerful anti-inflammatory effects, mimicking in some respects the beneficial effects of immunosuppressive drugs in these experimental models of autoimmune disease, but without discernable adverse effects.
(16) Temporal differences in the expression of sugar-binding proteins and different patterns of staining of the component cell types of human placenta were discerned, especially pronounced for alpha-fucoside-specific binding in the trophoblast and alpha-glucoside-specific binding in fetal and maternal macrophages.
(17) They’re all basically the same, but the tiny, barely discernible differences between them consume vast amounts of energy and generate heartache for everyone involved.
(18) Judged radiographically, partial obliteration (pulp chamber not discernible, root canal markedly narrowed but clearly visible) had occurred in 44 teeth (36%).
(19) Starch ingestion had no discernible effect on postprandial lipemia.
(20) We conclude that long-term prophylaxis with TMP-SMZ does not produce discernable hematologic, renal, or hepatic toxicity in renal transplant recipients nor does it augment nephrotoxicity with cyclosporine or increase the risk of rejection.
Keen
Definition:
(superl.) Sharp; having a fine edge or point; as, a keen razor, or a razor with a keen edge.
(superl.) Acute of mind; sharp; penetrating; having or expressing mental acuteness; as, a man of keen understanding; a keen look; keen features.
(superl.) Piercing; penetrating; cutting; sharp; -- applied to cold, wind, etc, ; as, a keen wind; the cold is very keen.
(superl.) Eager; vehement; fierce; as, a keen appetite.
(v. t.) To sharpen; to make cold.
(n.) A prolonged wail for a deceased person. Cf. Coranach.
(v. i.) To wail as a keener does.
Example Sentences:
(1) That the BBC has probably not been as vulnerable since the 1980s is also true – not least because the enemies of impartiality are more powerful, and the BBC's competitors (maimed after a year's exposure of their own behaviour in the Leveson inquiry ) are keen to wreck it.
(2) It has me as a listener and I am keen as well on sciences, arts, geography, history and politics, and I belong to two campaigns in Brighton and Chichester against privatisation of the NHS, and with some successes.
(3) Theresa May to visit India in signal of trading priorities post-Brexit Read more Cable said India had been keen to expand “ Mode 4 ” market access: the ability to bring in staff – Indian IT experts, for example – as part of trading in services.
(4) As corruption consistently ranks as a top concern for Spaniards, second only to unemployment, and with an eye on upcoming municipal and regional elections in the spring, Spain’s political parties have been keen to appear as if they are tackling the issue.
(5) He is understood to be keen to remain in the London area.
(6) The tech workers are mostly well-paid and keen to live downtown.
(7) Some Labour MPs, such as Frank Field and David Miliband, are keen on primaries.
(8) Professor Androsov was extremely hospitable and showed a keen interest in the freer exchange of knowledge between American and Soviet surgeons.
(9) The government, too, is keen to strike a conciliatory note, at least compared with the strident tones of the Iron Lady's day.
(10) Photograph: Peter Beaumont for the Guardian For his part the leader of Hadash, the veteran socialist party in Israel that emphasises Arab-Jewish cooperation, Odeh has now attracted a political star status most obvious on the stump in Lod on Wednesday in the repeated cries of “Ayman!” by shopkeepers and passersby keen to shake his hand or be photographed with him.
(11) This seemed contradictory for a government keen on getting people out of their cars, and given that at the time the Treasury finances were relatively healthy.
(12) Palaszczuk said she was keen to use her first attendance at a Coag meeting to push for the federal government to “accelerate some of their money towards the states” for the national disability insurance scheme.
(13) Even more striking is the stance being adopted by Hagan and her Democratic supporters, who have been as keen to discuss social issues as the Republicans have been to avoid them.
(14) Britain's estate agents today report a surge in the number of properties for sale amid signs jittery vendors are keen to strike a deal before next month's general election.
(15) It is a game to spend two hours together and enjoy our time together and say: ‘I was happy.’” Guardiola, who will be joined by the former Arsenal and Everton midfielder Mikel Arteta on his coaching staff , is keen to promote players from City’s junior ranks.
(16) May is thought to have been keen to examine more closely the role of Chinese companies in the project amid concerns about the impact on national security and despite her predecessor David Cameron’s strong support for Hinkley .
(17) Ian Livingstone is not all that keen on being photographed near the life-sized model of Lara Croft in his study – even though he was largely responsible for launching her on the world nearly 20 years ago, and the heroine of the Tomb Raider video games, comics and films helped to make his fortune.
(18) We were very keen to preserve the silhouette of the Leadenhall building [Cheesegrater],” says Richards.
(19) The Russians are also keen on it.” A Trump adviser confirmed the president-elect’s intention to meet Putin very soon and said that Reykjavik was under active consideration.
(20) At the same time, he is keen to do everything in his power to help Palace pick up three crucial points, right down to giving Pulis chapter and verse on the Cardiff players he knows inside out.