(n.) Want of continuity or cohesion; disunion of parts.
Example Sentences:
(1) Nulliparous women were also more likely to discontinue the condom because of pregnancy, as were non-Protestants and the Australian-born.
(2) The highest rate of discontinuation occurred when method choice was denied in the presence of husband-wife agreement on method choice, and the lowest rate occurred when method choice was granted in the presence of such concurrence.
(3) The patient recovered completely following discontinuation of antibiotics, transfusion of red blood cells, and treatment with glucocorticoids.
(4) We found that, although controlled release delivery of ddC inhibited de novo FeLV-FAIDS replication and delayed onset of viremia when therapy was discontinued (after 3 weeks), an equivalent incidence and level of viremia were established rapidly in both ddC-treated and control cats.
(5) Recently reported unfavorable clinical results (i.e., a high incidence of pain) have led to the discontinuation of one trial of porous polyethylene.
(6) When AMT administration was discontinued 40 hrs before precipitation of withdrawal the withdrawal pattern occurred with unchanged intensity.
(7) From the treatment group 23 patients could be assessed: 2 had discontinued clean intermittent self-catheterization due to urethral hemorrhage, 2 died during the observation period and 1 was lost to followup.
(8) It can induce acute cholinesterase poisoning, which is rapidly reversible on discontinuation of exposure.
(9) One patient had persistence of symptoms and findings 2 years after discontinuation of etretinate.
(10) Safety is increased through temporary discontinuation or dosage reduction of lithium in special risk situations.
(11) These studies demonstrate that vWF interaction with GP Ib may be modulated by botrocetin binding to a discontinuous site located within residues 539-643.
(12) Treatment with the antithyroid drug had been discontinued by herself when she was 19 years old until she was 24 years old, when she was pregnant and consulted our hospital.
(13) An isolation technique involving filtration and discontinuous density gradient centrifugation was utilized for obtaining Giardia lamblia cysts from human feces.
(14) The OPL first appears as a thin, discontinuous break in the cytoblast layer that is frequently interrupted by the profiles of migrating neuro- and glioblasts.
(15) In each of the four study sites, focus group discussions or in-depth interviews were held with potential acceptors, current NORPLANT users, discontinuers, husbands of women in these three groups, and service providers.
(16) No adverse reactions required the discontinuation of treatment.
(17) Nerve endings (synaptosomes) were isolated from homogenized rat brain corpora striata following centrifugation on discontinuous sucrose gradients.
(18) A wide but discontinuous distribution of the snail on the north coast of Haiti is confirmed (no autochthonous infections with S. mansoni have been reported).
(19) In 31 patients in whom specific IgE fell to low (less than 6% counts bound) or unmeasurable levels, immunotherapy was discontinued, and sting challenge was carried out 1 to 3 years later.
(20) Beta blockers should not be given to these patients or discontinued in cases which lack responsiveness.
Gap
Definition:
(n.) An opening in anything made by breaking or parting; as, a gap in a fence; an opening for a passage or entrance; an opening which implies a breach or defect; a vacant space or time; a hiatus; a mountain pass.
(v. t.) To notch, as a sword or knife.
(v. t.) To make an opening in; to breach.
Example Sentences:
(1) Linear and annular gap junctions between neighbouring cells were present, particularly in Group 1.
(2) We conclude that removal of dimers and repair of gaps were similar in all cases.
(3) Hence the major role of the 14-A arm of carboxybiotin is not to permit a large carboxyl migration but, rather to permit carboxybiotin to traverse the gap which occurs at the interface of three subunits and to insinuate itself between the CoA and keto acid sites.
(4) The junctional currents were already constant 1 ms after step changes in the junctional voltage; this was three orders of magnitude faster than the other known examples of voltage-controlled gap junctions between embryonic cells.
(5) These two enzymes may act jointly in filling up the gaps along the DNA molecule and elongating the DNA chain.
(6) Preliminary hearing results of 45 cases show air-bone gap closure of 67% within 10 dB and 98% within 20 dB.
(7) Measurements were made of the width of the marginal gap for three sites at each of four stages: (1) after the shoulder firing, (2) after the body-incisal firing, (3) after the glaze firing, and (4) after a correction firing.
(8) Office of National Statistics figures published in November last year showed that men earn 9.4% more than women, the lowest gender gap since records began in 1997.
(9) To a large extent, the failure has been a consequence of a cold war-style deadlock – Russia and Iran on one side, and the west and most of the Arab world on the other – over the fate of Bashar al-Assad , a negotiating gap kept open by force in the shape of massive Russian and Iranian military support to keep the Syrian regime in place.
(10) These activities define both the polarity of the anterior-posterior (AP) axis and the spatial domains of expression of the zygotic gap genes, which in turn control the subsequent steps in segmentation.
(11) After loss of permanent central incisors the treatment of choice could be either orthodontic closure or maintenance of the gap for a replacement-prosthetic, autotransplantation or implant.
(12) PTH, an inducer of shape change, did not affect the number of gap junctions appreciably.
(13) The primary aim of future work must still be directed toward preventing the formation of a gap between the restoration and the tooth.
(14) Since testosterone influenced both tissue stores and PDBu-stimulated secretion of LHRH and GAP, this steroid may selectively regulate biosynthesis and secretion of pro-LHRH-derived peptides through activation of the metabolic cascade involving the PKC system.
(15) Microsequencing of the peptides resolved by sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicates that the amino terminus of the protein is disposed at or near the cytoplasmic surface of the gap junction, and that this surface also contains a protease-hypersensitive hydrophilic sequence between residues 109 and 123, presumably connecting the second and third transmembrane segments.
(16) The present investigation shows that the intramembranous proteins of tight and gap junctions are mobile structures within the fluid membrane.
(17) The report also recommends including justice and victim of violence targets in the national Closing the Gap strategy, recognising foetal alcohol spectrum disorders as a disability before the courts, and making a national commitment to a justice reinvestment approach to find community-based solutions to youth crime.
(18) Regions within the desmosome where the two plasma membranes converged suggested that gap junctions were a component of the desmosome-like junctions.
(19) The frequency of chromosome and chromatid gaps and chromosome deletions was significantly higher among workers than among controls, and the same was true for the number of individuals with some type of chromosome alteration.
(20) Gap junctions were of different sizes and frequently composed of a small number of connexons organized in polygonal aggregates or linear arrays.