(n.) Want of continuity or cohesion; disunion of parts.
Example Sentences:
(1) Nulliparous women were also more likely to discontinue the condom because of pregnancy, as were non-Protestants and the Australian-born.
(2) The highest rate of discontinuation occurred when method choice was denied in the presence of husband-wife agreement on method choice, and the lowest rate occurred when method choice was granted in the presence of such concurrence.
(3) The patient recovered completely following discontinuation of antibiotics, transfusion of red blood cells, and treatment with glucocorticoids.
(4) We found that, although controlled release delivery of ddC inhibited de novo FeLV-FAIDS replication and delayed onset of viremia when therapy was discontinued (after 3 weeks), an equivalent incidence and level of viremia were established rapidly in both ddC-treated and control cats.
(5) Recently reported unfavorable clinical results (i.e., a high incidence of pain) have led to the discontinuation of one trial of porous polyethylene.
(6) When AMT administration was discontinued 40 hrs before precipitation of withdrawal the withdrawal pattern occurred with unchanged intensity.
(7) From the treatment group 23 patients could be assessed: 2 had discontinued clean intermittent self-catheterization due to urethral hemorrhage, 2 died during the observation period and 1 was lost to followup.
(8) It can induce acute cholinesterase poisoning, which is rapidly reversible on discontinuation of exposure.
(9) One patient had persistence of symptoms and findings 2 years after discontinuation of etretinate.
(10) Safety is increased through temporary discontinuation or dosage reduction of lithium in special risk situations.
(11) These studies demonstrate that vWF interaction with GP Ib may be modulated by botrocetin binding to a discontinuous site located within residues 539-643.
(12) Treatment with the antithyroid drug had been discontinued by herself when she was 19 years old until she was 24 years old, when she was pregnant and consulted our hospital.
(13) An isolation technique involving filtration and discontinuous density gradient centrifugation was utilized for obtaining Giardia lamblia cysts from human feces.
(14) The OPL first appears as a thin, discontinuous break in the cytoblast layer that is frequently interrupted by the profiles of migrating neuro- and glioblasts.
(15) In each of the four study sites, focus group discussions or in-depth interviews were held with potential acceptors, current NORPLANT users, discontinuers, husbands of women in these three groups, and service providers.
(16) No adverse reactions required the discontinuation of treatment.
(17) Nerve endings (synaptosomes) were isolated from homogenized rat brain corpora striata following centrifugation on discontinuous sucrose gradients.
(18) A wide but discontinuous distribution of the snail on the north coast of Haiti is confirmed (no autochthonous infections with S. mansoni have been reported).
(19) In 31 patients in whom specific IgE fell to low (less than 6% counts bound) or unmeasurable levels, immunotherapy was discontinued, and sting challenge was carried out 1 to 3 years later.
(20) Beta blockers should not be given to these patients or discontinued in cases which lack responsiveness.
Interstitial
Definition:
(a.) Of or pertaining to interstices; intermediate; within the tissues; as, interstitial cavities or spaces in the tissues of animals or plants.
Example Sentences:
(1) Developing seminiferous tubules and interstitial cells were first seen on day 26, and were well established one day later.
(2) Only group IV showed significant histological alterations such as glomerular sclerosis, interstitial damage, and increased glomerular area.
(3) The epithelial changes occur during the same time period that interstitial cells with ultrastructural and histochemical properties of steroid-secreting tissue appear in the ovarian stroma.
(4) However, cimetidine did not show any effect on the proliferation of collagenous fibers in the interstitial space of the mucosa.
(5) However, there is increasing evidence suggesting that interstitial protein distribution is nonuniform.
(6) Furthermore, the changes in both interstitial fluid and testicular venous blood levels of testosterone do not always parallel those in peripheral venous blood, suggesting that changes in testicular blood flow and peripheral clearance rates of testosterone may also be important in the control of circulating testosterone concentrations.
(7) Moreover, the most recent combined application of the rat interstitial cell testosterone (RICT) bioassay and a novel multiple-parameter deonvolution model has allowed investigators to dissect plasma concentration profiles of bioactive LH into defined secretory bursts, which have numerically explicit amplitudes, locations in time, and durations, and are acted upon by determinable subject- and study-specific endogenous metabolic clearance rates.
(8) As an extension of the previous study which indicated that mesoglea is a primitive basement membrane which has retained some characteristics of interstitial extracellular matrix, the present study was undertaken to analyze the role of mesoglea components during head regeneration in Hydra vulgaris.
(9) This can be done at the interstitial stage, when it cannot be detected by physical examination.
(10) After 40 minutes of coronary occlusion and 20 minutes of reflow, significant cardiac weight gain occurred in association with characteristic alterations in the ischemic region, including widespread interstitial edema and focal vascular congestion and hemorrhage and swelling of cardiac muscle cells.
(11) Lung biopsy in two patients and autopsy in two additional patients showed interstitial changes consistent with drug injury.
(12) These results have important implications for the understanding of renal interstitial autoimmune diseases as well as the interstitial nephritis that occurs in response to foreign Ag.
(13) They alter most immune functions and create a state of immunity deficiency; they damage the tubules which may lead to interstitial fibrosis and increased postglomerular capillary resistance furthering the trapping of macromolecules in the glomeruli; and they probably increase tissue permeability to macromolecules.
(14) A minor portion of the lymph is produced also in the lymph-fold from where it is transported in the interstitial tissue either by transfer vesicles of the circulatory blood capillaries or by pores and fenestrae of the transudatory blood capillaries.
(15) Comparison of these theoretical results with variations in reabsorption observed in micropuncture studies makes it possible to place upper and lower bounds on the difference between interstitial oncotic and hydrostatic pressures in the renal cortex of the rat.
(16) This has shown that, in spite of higher dose rates in the corridor areas because of the use of an MDR system and the increase in interstitial techniques, the doses to ward nurses have been significantly reduced by encouraging staff to comply with the ALARA principle and the introduction of afterloading systems.
(17) Among the tubulo-interstitial lesions subcapsular interstitial fibrosis, acute tubular necrosis, cellular tubulo-interstitial rejection and Ciclosporin associated lesions are briefly described.
(18) Tubules were perfused with a control solution that resembled interstitial fluid but lacked calcium.
(19) Fluid overload, which could have been caused by the hyperosmolar properties of dextran, worsened progressively as fluids were drawn from the interstitial space and urine output was reduced.
(20) Four hours after infusion, the animals displayed a clinical and pathological pattern which closely resembled post-traumatic acute respiratory distress syndrome, including hypoxia, hypocarbia, thrombocytopenia, increased pulmonary capillary permeability to albumin, interstitial edema, hypertrophy of alveolar lining cells, and intra-alveolar hemorrhage.