(n.) Lack of ease; uneasiness; trouble; vexation; disquiet.
(n.) An alteration in the state of the body or of some of its organs, interrupting or disturbing the performance of the vital functions, and causing or threatening pain and weakness; malady; affection; illness; sickness; disorder; -- applied figuratively to the mind, to the moral character and habits, to institutions, the state, etc.
(v. t.) To deprive of ease; to disquiet; to trouble; to distress.
(v. t.) To derange the vital functions of; to afflict with disease or sickness; to disorder; -- used almost exclusively in the participle diseased.
Example Sentences:
(1) Forty-nine patients (with 83 eyes showing signs of the disease) were followed up for between six months and 12 years.
(2) However, as other patients who lived at the periphery of the Valserine valley do not appear to be related to any patients living in the valley, and because there has been considerable immigration into the valley, a number of hypotheses to explain the distribution of the disease in the region remain possible.
(3) A 2.5-month-old child with cyanotic heart disease who required long-term PGE1 infusions; developed widespread periosteal reactions during the course of therapy.
(4) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(5) Among the pathological or abnormal ECGs (25.6%) prevailed the vegetative-functional heart diseases with 92%.
(6) Clinical signs of disease developed as early as 15 days after transition to the experimental diets and included impaired vision, decreased response to external stimuli, and abnormal gait.
(7) These results suggest the presence of a new antigen-antibody system for another human type C retrovirus related antigens(s) and a participation of retrovirus in autoimmune diseases.
(8) We considered the days of the disease and the persistence of symptoms since the admission as peculiar parameters between the two groups.
(9) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(10) Coronary arteritis has to be considered as a possible etiology of ischemic symptoms also in subjects who appear affected by typical atherosclerotic ischemic heart disease.
(11) Of 19 patients with coronary artery disease and "normal" omnicardiograms, only 8 (42%) had normal ventricular angiography.
(12) A disease in an IgD (lambda) plasmocytoma is described, where after therapy with Alkeran and prednisone a disappearance of all clinical and laboratory findings indicating an activity could be observed.
(13) In order to control noise- and vibration-caused diseases it was necessary not only to improve machines' quality and service conditions but also to pay special attention to the choice of operators and to the quality of monitoring their adaptation process.
(14) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(15) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(16) Diseases of the gastric musculature, including the inflammatory and endocrine myopathies, muscular dystrophies, and infiltrative disorders, can result in significant gastroparesis.
(17) In patients with coronary artery disease, electrocardiographic signs of left atrial enlargement (LAE-negative P wave deflection greater than or equal to 1 mm2 in lead V1) are associated with increased left ventricular end diastolic pressure (LVEDP).
(18) Road traffic accidents (RTAs) comprised 40% and ischaemic heart disease (IHD) 13% of the total.
(19) We measured soluble CD8 (sCD8) levels in the CSF of patients with MS, other inflammatory neurologic diseases (INDs), and noninflammatory neurologic diseases (NINDs).
(20) Measurement of urinary GGT levels represents a means by which proximal tubular disease in equidae could be diagnosed in its developmental stages.
Inveterate
Definition:
(a.) Old; long-established.
(a.) Firmly established by long continuance; obstinate; deep-rooted; of long standing; as, an inveterate disease; an inveterate abuse.
(a.) Having habits fixed by long continuance; confirmed; habitual; as, an inveterate idler or smoker.
(a.) Malignant; virulent; spiteful.
(v. t.) To fix and settle by long continuance.
Example Sentences:
(1) It is noteworthy that intracardiac evaluation is necessary when there is longstanding and inveterate tachyarrhythmia in otherwise healthy children.
(2) Graham, an inveterate jokester, slightly undermined the moment by joking shortly afterwards: “I feel like I’m on Oprah.” Facebook Twitter Pinterest Lindsey Graham wipes away tears while speaking at the Family Leadership Summit.
(3) Authors describe the operative method of Iselin for the treatment of inveterated extensor tendon injuries over the DIP joint and their results.
(4) Resorting to a series of Ted the swordsman scenes which may merely be the lurid fantasies of the heroine, director Christine Jeffs never makes it clear whether Hughes was a rampaging philanderer whose sexual conquests and general obliviousness to Plath's mounting depression led to her demise, or a man driven into other women's arms by his wife's chronic melancholy - perhaps the most time-honoured excuse of the inveterate tomcat - or both.
(5) The Man Who Can't Keep His Clothes On ( Thursday, 10pm, C4 ) catalogues his achievements while following this inveterate attention-seeker as he plans his testicular swan song.
(6) Cyril Smith , the late Liberal MP, accused since his death in 2010 of being an inveterate child abuser, was said to visit the property.
(7) It is the authors' opinion that, taking into account the late results following operative reduction of inveterate femoral dislocation, the operation of arthrodesis of the coxa is felt to be more rational in such cases.
(8) What the authors mean by locked dislocation of the shoulder is an inveterate posterior dislocation of the humeral head which remains locked within the glenoid cavity as a result of anatomopathological lesion.
(9) This action may prove of value in the treatment of ulcer patients who are inveterate smokers, alcohol users or who are compelled to consume non-steroidal anti-inflammatory drugs for pain relief from rheumatic and allied diseases.
(10) This method has been used in the complex treatment of 12 patients with acute and inveterate injuries of the thoracic and the thoracolumbar departments of the spinal column and of the spine.
(11) Correction osteotomy of the bones of both forearms with excision of the radial head is recommended for inveterate cases.
(12) This technique, based on transganglionic regulation--a novel neurobiological principle discovered by Csillik and Knyihár-Csillik-, alleviated pain in both fresh and inveterated PHN cases.
(13) Personally, I’ll believe we’re getting somewhere when Channel 4 puts on Corporate-Benefits Street – with White Dee replaced by Amazon founder and inveterate tax-dodger Jeff Bezos.
(14) The authors report 9 cases of acetabular fracture, 6 recent complex and 3 inveterate, treated surgically through the lateral incision of Letournel.
(15) A tall, well-built man with an imposing physical presence, Sherrin was an inveterate first-nighter, always enjoying a couple of stiff Martinis before the show and a good supper afterwards.
(16) A chronic slip of the upper femoral epiphysis (also called by the authors inveterate epiphysiolysis) is a rare, but not an extremely rare, occurrence.
(17) The number of daily cigarettes consumed by inveterate smokers is considerably and lastingly reduced, and 27 p. cent of the patients quit smoking.
(18) Nevertheless, the high incidence of often serious complications makes the combined anterior-posterior approach preferable for severe inveterate fractures of the acetabulum.
(19) The authors present an analysis of the results of operative treatment for inveterate femoral dislocations in 13 patients, in 6 of them open reduction of the dislocation was performed, in 6--arthrodesis of the coxa, in 1--subtrochanteric osteotomy.
(20) In a 25-year-old female patient with right-sided adnex tumour and inveterate infection on the urinary tract a benign cystic teratoma (dermoid cyst) perforated into the lumen of the urinary bladder could diagnosed cystoscopically.