(superl.) Inclined to drowse; heavy with sleepiness; lethargic; dozy.
(superl.) Disposing to sleep; lulling; soporific.
(superl.) Dull; stupid.
(1) YOH shifted the healthy subjects' mood towards feeling panicked, elevated systolic blood pressure and plasma prolactin concentrations, reduced digit symbol substitution, and induced drowsiness and passiveness.
(2) Side-effects (pruritus, nausea, vomiting, drowsiness) were also noted.
(3) MIDAZOLAM IS SUPERIOR TO DIAZEPAM IN CERTAIN WAYS: it has a more rapid onset; produces greater anterograde amnesia, less postoperative drowsiness, less venous irritation and less likelihood of thrombophlebitis development.
(4) Drowsiness and altered taste perception were increased significantly over placebo only in the high-dose azelastine group.
(5) Long-acting drugs and techniques that are associated with excessive drowsiness or nausea and vomiting should not be utilized.
(6) At altitude, temazepam led to less wakefulness and to drowsy sleep--there were no prolonged sleep latencies.
(7) The lowest recovery rate was observed in drowsy patients operated on between 4 and 10 days from the hemorrhage.
(8) Fatigue, drowsiness, and attention were self-rated using visual analogue scales; oral temperature was self-measured and a letter cancellation test was performed.
(9) Experimental evidence shows that during drowsiness, disfacilitation in thalamic and cortical neurons (by partial removal of influences from mesopontine, posterior hypothalamic, and basal forebrain activating systems) may coexist with active hypnogenic mechanisms.
(10) Ethanol alone impaired manual dexterity, increased drowsiness, reduced 'clearheadedness' and also tended to reduce feelings of aggression.
(11) However, both isomers showed different effects on the EEG and animal's behavior following convulsions; e.g., the cocaine-induced convulsions were followed by low-voltage fast waves in the EEGs associated with behavioral hyperexcitation, while pseudococaine-induced convulsions were followed by high-voltage slow waves associated with behavioral depression and drowsiness with intermittent sleep.
(12) However, mice treated topically with spiperone, unlike those treated systemically, exhibited no drowsiness or other evidence of central nervous system effects.
(13) The drug reduced the frequency of transitions into wakefulness and stage 1 (drowsiness) and reduced the time spent in stage 1; there was a withdrawal rebound.
(14) Adverse reactions to phenothiazines, including hypotension, sedation, drowsiness, extrapyramidal symptoms, tardive dyskinesia, cardiac toxicity and agranulocytosis, are often more common and severe than those attributed to narcotic analgesics.
(15) Apomorphine produced severe drowsiness in the PPS patients.
(16) Patients who received lorazepam or oxazepam also experienced significantly more severe drowsiness than those patients receiving methylprednisolone (both P less than 0.001).
(17) Side effects (principally drowsiness, ataxia, headache) occurred mainly during the initiation of therapy and decreased during therapy.
(18) Adverse effects of H1 blockers on the brain, such as drowsiness, may be produced as a consequence of this inhibitory action.
(19) The differences included slower alpha and more theta during THC experiences, reminiscent of initial drowsiness EEG, and of some results in schizophrenia.
(20) Neurological examination on admission: The patient was in drowsy state, papilledema on the both sides and right hemiparesis including the face were noted.
(a.) Causing sleep; tending to cause sleep; soporiferous; as, the soporific virtues of opium.
(n.) A medicine, drug, plant, or other agent that has the quality of inducing sleep; a narcotic.
(1) The maximum soporific effect did not occur until 90-120 s after injection.
(2) His answer threatened a soporific summer-long contest that would expose a great gap between the self-styled people's party and the people themselves.
(3) 'P ublic sector commissioning": I can't think of a phrase that conveys something so important and yet sounds so soporific.
(4) Soporific effect of hexenal was distinctly increased in the burns, which correlated to the severity of thermic impairment.
(5) Pebble-dashed walls, red roof tiles, Velux windows, cherry trees... these things make me think not of daring strokes of oil on canvas, but of the safe, the soporific - a round of golf, perhaps, or a gentle Sunday-night sitcom.
(6) Less drugs were used in general, and the use of tranquillizers and soporifics was cut down to a third.
(7) Higher doses of naloxone (1Opmol into the LC) were however, required to antagonize the behavioural and ECoG soporific effects induced by the Kappa-receptor agonist U 50,488H.
(8) The drug is well tolerated by the patients and does not produce any inhibitory or soporific action.
(9) And, intriguingly, a 2009 study at Mashhad University in Iran revealed an extract of saffron did have soporific qualities, on mice at least.
(10) Instead, the atmosphere is soporific, with an underlying threat of menace.
(11) Toxicological urine analysis for drugs--directed mainly at soporifics, sedatives, tranquilizers, and pain-relievers--on 84 patients involved in industrial accidents yielded the following results.
(12) What had been a sombre occasion for City fans as they looked at an Etihad Stadium dugout without Mancini for a first time since December 2009 became further muted when a soporific start to the game had ended with Anthony Pilkington opening the scoring for Norwich.
(13) 1 Experiments were performed on a variety of tissues from different species to establish whether or not the properties of p-chlorophenylalanine methyl ester (PCPA) included a 5-hydroxytryptamine (5-HT)-like action which might explain the soporific action of PCPA in chicks.
(14) Because of their pharmacologic action, alcohol and high doses of soporifics used as remedies may produce REM-deficit sleep and actually prolong insomnia.
(15) Imagine my surprise in the morning to find it was gone 7am – the soporific effect of the loud snoring made my baby sleep through the night for the first time!
(16) Long sleep (LS) and short sleep (SS) mice have a differential sensitivity to the behavioral actions of an adenosine agonist, R-phenylisopropyl-adenosine (PIA) that parallels their differential sensitivity to the soporific effects of ethanol.
(17) If so, the soporific way Per Mertesacker dawdled in possession and Kieran Gibbs clumsily punted the ball into the air suggested there had been scant impact.
(18) After 53 days of alcohol ingestion there was no evidence of tolerance to the soporific effects of parenterally administered ethanol and removal of the ethanol solutions failed to produce any signs of alcohol withdrawal.
(19) Further, much evidence also supports the conclusion that most of these hypnotic-depressants and anesthetics could exert their soporific influence by a potentiation of GABA activity.
(20) Recent evidence, as well as reevaluated previous evidence, indicates that Long-Sleep mice are more sensitive to the soporific effects of three major classes of CNS depressants (alcohols, barbiturates, and benzodiazepines), as well as many other anesthesia-inducing compounds (adenosine, chloral hydrate, trichloroethanol, paraldehyde, nitrous oxide, enflurane, and isoflurane).