(n.) A thick, ill-shapen piece; a clumsy leaden counter used by boys in playing chuck farthing.
(v. t.) A dull, gloomy state of the mind; sadness; melancholy; low spirits; despondency; ill humor; -- now used only in the plural.
(v. t.) Absence of mind; revery.
(v. t.) A melancholy strain or tune in music; any tune.
(v. t.) An old kind of dance.
(v. t.) To knock heavily; to stump.
(v. t.) To put or throw down with more or less of violence; hence, to unload from a cart by tilting it; as, to dump sand, coal, etc.
(n.) A car or boat for dumping refuse, etc.
(n.) A ground or place for dumping ashes, refuse, etc.
(n.) That which is dumped.
(n.) A pile of ore or rock.
Example Sentences:
(1) The dumping-syndrome is a severe complication of gastric surgery after operations which destroy or weaken the sphincter mechanism of the pylorus.
(2) And when it looked like they could get away with no legislation, they dumped US CAP completely.
(3) Michaelis constants for (+)5,10-methylene-5,6,7,8-tetrahydrofolate [(+)CH2H4folate] were 0.014 mM in the case of methylation of 2'-deoxyuridine-5'-phosphate (dUMP) and 0.55 mM when it served as methyl-group donor for 2'-fluoro-2'-deoxyuridine-5'-phosphate (dUflMP); the corresponding Km values for dUMP and dUflMP were 0.01 mM and 0.11 mM, respectively.
(4) The persona that emerged during day two of Breivik's 10-week trial was a rambling, repetitive obsessive, fixated on a threat he never truly managed to articulate, but which involved "cultural Marxists", whom he claimed had destroyed Norway by using it as "a dumping ground for the surplus births of the third world".
(5) As part of a concerted effort to avoid the in danger listing, the Queensland government came up with an alternative plan to dump the sediment within an enclosed area of the Caley Valley wetlands, which is considered nationally important habitat for more than 15 species of migratory birds.
(6) Acanthamoeba culbertsoni was isolated from a sewage-spoil dump site near Ambrose Light, New York Bight.
(7) The binding characteristics of the substrate analogue 5-fluoro-2'-deoxyuridylate (FdUMP) could be clearly distinguished from that of dUMP by comparing their binding in phphate and Tris-HCl.
(8) It appears from these studies that ;dumping' is due to rapid gastric emptying and mainly due to the drainage procedure.
(9) dUMP binary complex can be isolated and conveniently assayed by nitrocellulose disc filtration using [6-3H]dUMP as the radioactive ligand.
(10) The previous government advanced five major dredge projects involving dumping in the marine park,” he said.
(11) Undergraduates dump each other with lines like: "Going out with you is like dating a Stairmaster."
(12) The incidence of dumping after truncal or selective vagotomy with pyloroplasty and highly selective vagotomy without a drainage procedure was assessed both clinically and experimentally.
(13) Responding to a question from host Karl Stefanovic about Kyrgios’s behaviour at Wimbledon and Tomic’s attack on Tennis Australia , which led to him being dumped from the Davis Cup team, Fraser said: “They should be setting a better example for the younger generation of this country, a great country of ours.” “If they don’t like it, go back to where their fathers or their parents came from.
(14) We will receive the full impact of the waste when they start dumping.
(15) Four patients had severe dyspeptic symptoms and four severe dyspepsia plus dumping.
(16) Cytotoxicity resulting from dUMP misincorporation was consistent with the enhanced toxicity of piritrexim which was observed when HL-60 cells or MOLT-4 cells were exposed concurrently to exogenous deoxyuridine.
(17) In the thirties the subdivision into a so-called early and late dumping syndrome follows.
(18) What’s fair about this generation dumping our burdens on our children and grandchildren?
(19) A recent study suggests that coral disease is doubled when dredging occurs near reefs, although supporters of the dredging have repeatedly insisted it can be done safely and that the Abbot Point sediment will be dumped around 40km from the nearest reef.
(20) • As Firefox dumps Google for Yahoo, is the clock ticking for Mozilla?
Ere
Definition:
(adv.) Before; sooner than.
(adv.) Rather than.
(v. t.) To plow. [Obs.] See Ear, v. t.
Example Sentences:
(1) At saturating concentrations of ER, plasmids bearing one, two, and four EREs in tandem bound approximately one, two, and four dimeric ER molecules, respectively.
(2) Interestingly, each of these fragments had a perfect palindromic estrogen responsive element (ERE) (GGT-CANNNTGACC).
(3) These data suggest that flanking DNA sequences may exert a significant effect on the activity of EREs as hormone-dependent transcription activators.
(4) In 11 spontaneously breathing patients with chronic obstructive pulmonary disease (COPD) in acute ventilatory failure, we measured the total inspiratory (WItot) and total resistive (WI + Eres) work rate of breathing, together with lung mechanics (dynamic pulmonary elastance and inspiratory and expiratory pulmonary flow resistance).
(5) This element binds to the estrogen receptor in vitro as assessed by gel retardation assay similar to the vitellogenin gene ERE.
(6) The two polypeptides are different as judged by peptide mapping, and only the 85-kDa polypeptide can be cross-linked to the bromodeoxyuridine-substituted synthetic ERE by UV irradiation.
(7) Two methods have been suggested for the calculation of pHapp and the loss of activity on particle preparation, these methods are based on the use of the ERE in conjunction with experimental data.
(8) These results suggest that the ability of ER and TR to functionally discriminate between an ERE and a TRE is a result of dimerization of their DBDs.
(9) The presence of the biologically active hER is confirmed in co-injection experiments, in which HEO is co-introduced with a CAT reporter gene under the control of a vitellogenin promoter containing or lacking the ERE.
(10) Gene transfer experiments using estrogen-responsive cells have shown that the 13 bp perfect palindromic element GGTCACTGTGACC found upstream of the Xenopus laevis vitellogenin gene A2 promoter mediates hormonal stimulation and thus, was called the estrogen-responsive element (ERE).
(11) The ovalbumin promoter half-palindromic ERE motif located close to the TATA box was required for the activity of the distal DH3 ERE, but could be replaced by the binding sites of other transactivators.
(12) The equilibrium constant for the redox equilibration of fatty acid synthase in a glutathione redox buffer is 15 mM (Ered + GSSG in equilibrium Eox + 2GSH).
(13) When sequenced, these elements showed remarkable diversity and were different from the consensus vitellogenin A2 ERE.
(14) However at 32 degrees C Ta, there was an increase in rectal temperature in response to haloperidol application; this hyperthermia was due to a decrease in both the ear blood flow and respiratory evaporative heat loss (Eres).
(15) The affinity of estradiol binding to receptors was reduced only 2- and 5-fold, respectively, in the double and quadruple Cys to Ala mutants, and estradiol was an effective stimulator of transcription from an estrogen-responsive reporter gene [(ERE)2-TATA-CAT].
(16) A stimulatory estrogen response element (ERE) was localized to a 32-bp region between -547 and -516 bp.
(17) In these genes, two ERE homologues, which have only low, if any, regulatory capacity on their own, act synergistically to achieve high estrogen inducibility.
(18) "Gnnmph, I can't 'ave it 'ere, I 'aven't 'ad my enema," wails a labouring housewife, straining fruitlessly on a communal tenement bog as horrified neighbours look on in their rollers.
(19) This ERE also mediated down-regulation by progestins in the presence of the progesterone receptor, even though it has no progesterone receptor binding ability.
(20) This 67 bp region contains a consensus for the core sequence of the glucocorticoid responsive element (GRE) and the estrogen responsive element (ERE).