(n.) The act of going out or leaving, or the power to leave; departure.
(n.) The passing off from the sun's disk of an inferior planet, in a transit.
(v. i.) To go out; to depart; to leave.
Example Sentences:
(1) Spermine clearly activated 45Ca uptake by coupled mitochondria, but had no effect on Ca2+ egress from mitochondria previously loaded with 45Ca.
(2) C-particles were present in t-tubules, which were possible intracellular viaducts of infection or dissemination and perhaps were the loci of receptors of viral invasion of the cytoplasm and sites of egress.
(3) Adherence of PMNs to the endothelium and their subsequent diapedesis and egress to areas of infection are considered early vital events in the inflammatory process.
(4) These findings indicate that BFA-induced retrograde movement of molecules from the Golgi complex to the endoplasmic reticulum early in infection arrests the ability of host cells to support maturation and egress of enveloped viral particles.
(5) In addition, IL-1ra and 35F5 significantly blocked the ability of IL-1 to stimulate egress of PMN from bone marrow, to induce a transient neutrophilia, and to elevate serum levels of hepatic acute phase proteins, IL-6, and corticosterone.
(6) During the 2nd hr, there is an influx of neutrophils into the region, and these form a thick layer around the staphylococcal clumps and, apparently, prevent further egress of toxin.
(7) It was expressed by a positive sloping sigmoidal function that defines the egress potential fo the cells that increases with cell maturation.
(8) The growth is associated with the intensified egress of circulating fibrinogen into the extravascular space (thrombus, tissue, etc.).
(9) The prior existence of HEVs in uninvolved psoriatic skin could account for the rapid egress of T8 lymphocytes from the vasculature to the epidermis in response to trauma.
(10) The rate of egress of albumin from blood vessels has been estimated from the initial slope of the ratio of extravascular radioactivity in the tissue to plasma radioactivity plotted against time after injection of 125I-albumin.
(11) Vasculitis, a common but frequently unappreciated event, may produce nonspecific tissue damage via hemorrhage and ischemia in addition to providing a mechanism for egress of inflammatory factors into the areas of virus-induced cellular damage.
(12) In this report, we show that gro29 cells harbor a lesion that inhibits the egress of HSV-1 virions during infection.
(13) External chloride and sulphate were able to trans-accelerate the egress of labelled sulphate from tissue fragments via a DIDS-inhibitable route.
(14) These results support the hypothesis that erythrocyte egress may be driven by a hydrostatic pressure difference across the pore.
(15) Inhibitors of lysosomal acidification (4,4'-di-isothiocyanostilbene-2,2'-disulphonate, NN'-dicyclohexylcarbodi-imide, carbonyl cyanide m-chlorophenylhydrazone, NH4Cl and methylamine hydrochloride) did not alter cystine egress or countertransport in polymorphonuclear-leucocyte lysosome-rich granular fractions at pH 7.0.
(16) Bone marrow examination revealed that the neutrophilia was secondary to egress and mild depletion of the neutrophil storage pool but that the neutrophil storage pool later returned to normal.
(17) The kinetic patterns of uptake and egress of radioactivity in striatum and cerebellum as well as the magnitude of the uptake was very similar with the two tracers.
(18) We propose that T cells can modify the vascular endothelium in certain areas to allow egress of DC from the bloodstream.
(19) Sixteen patients with complex cyanotic congenital heart disease underwent an operation involving the use of the aorta and the main pulmonary artery as the egress for systemic arterial blood flow (the Damus-Kaye-Stansell operation, modified as discussed).
(20) The drug enhanced vasoactive intestinal polypeptide (VIP)-stimulated PRL-secretion, while thyroliberin (TRH)- and 12-0-tetradecanoyl phorbol-13-acetate (TPA)-elicited PRL egress were slightly reduced indicating a cAMP-mediated reduction of protein kinase C (PK-C) mediated PRL release.
Issue
Definition:
(n.) The act of passing or flowing out; a moving out from any inclosed place; egress; as, the issue of water from a pipe, of blood from a wound, of air from a bellows, of people from a house.
(n.) The act of sending out, or causing to go forth; delivery; issuance; as, the issue of an order from a commanding officer; the issue of money from a treasury.
(n.) That which passes, flows, or is sent out; the whole quantity sent forth or emitted at one time; as, an issue of bank notes; the daily issue of a newspaper.
(n.) Progeny; a child or children; offspring. In law, sometimes, in a general sense, all persons descended from a common ancestor; all lineal descendants.
(n.) Produce of the earth, or profits of land, tenements, or other property; as, A conveyed to B all his right for a term of years, with all the issues, rents, and profits.
(n.) A discharge of flux, as of blood.
(n.) An artificial ulcer, usually made in the fleshy part of the arm or leg, to produce the secretion and discharge of pus for the relief of some affected part.
(n.) The final outcome or result; upshot; conclusion; event; hence, contest; test; trial.
(n.) A point in debate or controversy on which the parties take affirmative and negative positions; a presentation of alternatives between which to choose or decide.
(n.) In pleading, a single material point of law or fact depending in the suit, which, being affirmed on the one side and denied on the other, is presented for determination. See General issue, under General, and Feigned issue, under Feigned.
(v. i.) To pass or flow out; to run out, as from any inclosed place.
(v. i.) To go out; to rush out; to sally forth; as, troops issued from the town, and attacked the besiegers.
(v. i.) To proceed, as from a source; as, water issues from springs; light issues from the sun.
(v. i.) To proceed, as progeny; to be derived; to be descended; to spring.
(v. i.) To extend; to pass or open; as, the path issues into the highway.
(v. i.) To be produced as an effect or result; to grow or accrue; to arise; to proceed; as, rents and profits issuing from land, tenements, or a capital stock.
(v. i.) To close; to end; to terminate; to turn out; as, we know not how the cause will issue.
(v. i.) In pleading, to come to a point in fact or law, on which the parties join issue.
(v. t.) To send out; to put into circulation; as, to issue notes from a bank.
(v. t.) To deliver for use; as, to issue provisions.
(v. t.) To send out officially; to deliver by authority; as, to issue an order; to issue a writ.
Example Sentences:
(1) You lot have got real issues to talk about and deal with.
(2) The issue of the Schizophrenia Bulletin is devoted to articles representing this full range of conceptual and empirical work on first-episode psychosis.
(3) I’m not in charge of it but he’s stood up and presented that, and when Jenny, you know, criticised it, or raised some issues about grandparent carers – 3,700 of them he calculated – he said “Let’s sit down”.
(4) Issues such as healthcare and the NHS, food banks, energy and the general cost of living were conspicuous by their absence.
(5) Before issuing the ruling, the judge Shaban El-Shamy read a lengthy series of remarks detailing what he described as a litany of ills committed by the Muslim Brotherhood, including “spreading chaos and seeking to bring down the Egyptian state”.
(6) Critics say he is unelectable as prime minister and will never be able to implement his plans, but he has nonetheless pulled attention back to an issue that many thought had gone away for good.
(7) Much of the current information concerning this issue is from short-term studies.
(8) It is entirely proper for serving judges to set out the arguments in high-profile cases to help public understanding of the legal issues, as long as it is done in an even-handed way.
(9) It has announced a four-stage programme of reforms that will tackle most of these stubborn and longstanding problems, including Cinderella issues such as how energy companies treat their small business customers.
(10) One man has died in storms sweeping across the UK that have brought 100-mile-an-hour winds and led to more than 50 flood warnings being issued with widespread disruption on the road and rail networks in much of southern England and Scotland.
(11) The issue has been raised by an accountant investigating the tax affairs of the duchy – an agricultural, commercial and residential landowner.
(12) They are just literally lying.” In August Microsoft severed its ties, saying Alec’s stance on climate change and several other issues “conflicted directly with Microsoft’s values”.
(13) One is that the issue of whether the World Cup should go ahead in Russia and Qatar still firmly remains on the table.
(14) The data indicate greater legitimacy and openness in discussing holocaust-related issues in the homes of ex-partisans than in the homes of ex-prisoners in concentration camps.
(15) That’s a criticism echoed by Democrats in the Senate, who issued a report earlier this month criticising Republicans for passing sweeping legislation in July to combat addiction , the Comprehensive Addiction and Recovery Act (Cara), but refusing to fund it.
(16) It can feel as though an official opinion has been issued.
(17) The first part of this survey which dealt with equipment for the anterior segment was published in a previous issue of this journal.
(18) Problem definition, the first step in policy development, includes identifying the issues, discussing and framing the issues, analyzing data and resources, and deciding on a problem definition.
(19) Heathrow, likewise, said Gatwick's new runway would not solve the issue of hub capacity.
(20) The deep green people who have an issue with the language of natural capital are actually making the same jump from value to commodification that they state that they don’t want ... They’ve equated one with the other,” he says.