(v. t.) To make clear or manifest; to render more intelligible; to illustrate; as, an example will elucidate the subject.
Example Sentences:
(1) Further studies are required to elucidate specific roles of the steroid-induced proteins in the effects of glucocorticoids on HTM and HS cells.
(2) To elucidate the mechanisms by which indomethacin lowers proteinuria, we studied 20 patients with the nephrotic syndrome.
(3) Its pathogenesis, still incompletely elucidated, involves the precipitation of immune complexes in the walls of the all vessels.
(4) The data shows a dissociation between ferritin synthesis, cellular accumulation and secretion for which the mechanisms have still to be elucidated.
(5) An attempt was made to elucidate possible participation of low molecular weight nuclear RNA's (LMWN RNA's) in the transcription process.
(6) Although lipopolysaccharides seem to play a significant role in the final assembly of the trimeric porins, the details of the targeting process still remain to be elucidated.
(7) This situation highlights the potential importance of molecules with different inheritance patterns in elucidating complex cases of reticulate evolution.
(8) Glucan (mol wt 3000) structure was elucidated by methylation and periodate oxidation techniques.
(9) The relative importance of each of these growth factors in the in vivo situation will have to be elucidated by future studies using specific receptor antagonists or neutralizing antibodies.
(10) Although numerous studies have documented the effects of the renal nerves on kidney function, the mechanisms involved in the diuresis have yet to be elucidated.
(11) While the precise function of the MIRP is not known, the availability of this protein in pure and biologically relevant quantities will allow further studies to elucidate its pathobiologic function.
(12) To elucidate the role of arterial baroreceptors in the acute regulation of arterial pressure in the conscious animal, arterial pressure was lowered and raised in intact, conscious dogs, and in dogs after bilateral section of both carotid sinus and aortic nerves (total arterial baroreceptor denervation, TABD).
(13) It appears that irrespective of the elucidation of the nature of the putative aetiological factor (presumed to be viral) in MS, the arrest and reversal of T cell-related events within the CNS in this devastating condition represent feasible goals and should remain a major target for some time to come.
(14) Interaction between aromatic diamidines (pentamidine, propamidine, and stilbamidine) and nucleic acids were studied to elucidate the mechanism underlying renal toxicity included by pentamidine in patients.
(15) Experiments elucidating the mechanism behind this effect are described.
(16) Until further elucidation of the causes of altered thiopental metabolism is available to identify patients more likely to have elevated concentrations of pentobarbital, monitoring of blood drug concentrations in patients receiving thiopental should include determination of both thiopental and pentobarbital concentrations.
(17) The constitutent fatty acids were elucidated by gas chromatography and mass spectrometry to be beta-hydroxy isodecanoic acid, beta-hydroxy decanoic acid, beta-hydroxy isoundecanoic acid and beta-hydroxy anteisoundecanoic acid.
(18) The curiously double nature of the virgin in this tale, her purity versus her duplicity, seems unquestionably related to the infantile split mother, as elucidated by Klein--a connection explored in an earlier paper.
(19) We reviewed our experience with 245 thyroidectomies to define the spectrum of hypocalcemia, elucidate the mechanisms of hypocalcemia, and formulate a rational basis for its management.
(20) Effect of electroconvulsive shock (ECS) on central serotonin (5-HT) receptor function was studied in order to elucidate its antidepressive mechanism.
Investigate
Definition:
(v. t.) To follow up step by step by patient inquiry or observation; to trace or track mentally; to search into; to inquire and examine into with care and accuracy; to find out by careful inquisition; as, to investigate the causes of natural phenomena.
(v. i.) To pursue a course of investigation and study; to make investigation.
Example Sentences:
(1) Lebedev says he is aware that he is under investigation.
(2) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(3) Lucy and Ed will combine coverage of hard and breaking news with a commitment to investigative journalism, which their track record so clearly demonstrates”.
(4) Clinical and roentgenographic criteria could not discriminate between patients with and without pneumonia, confirming the findings of previous investigations.
(5) The combined immediate and delayed responses to fleas in the dog are as observed by other investigators in man and guinea pigs.
(6) "As the investigation remains live and in order to preserve the integrity of that investigation, it would not be appropriate to offer further comment."
(7) The main clinical features pertaining to the concept of the "psycho-organic syndrome" (POS) were investigated in a sample of children who suffered from severe craniocerebral trauma.
(8) The ability of azelastine to influence antigen-induced contractile responses (Schultz-Dale phenomenon) in isolated tracheal segments of the guinea-pig was investigated and compared with selected antiallergic drugs and inhibitors of arachidonic acid metabolism.
(9) Electronmicroscopical investigations have revealed that, under normal conditions, a minor vesicular transfer of intravenously injected peroxidase occurs across the endothelium in segments of arterioles, capillaries and venules, especially in arterioles with a diameter about 15-30 mu.
(10) Using mini-pigs with an indwelling vascular catheter, the pharmacokinetics of chloramphenicol were investigated in healthy and liver-damaged animals.
(11) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(12) The quaternary structure of ribonucleotide reductase of Escherichia coli was investigated, with the use of purified B1 and B2 proteins and bifunctional cross-linking agents.
(13) We have investigated a physiological role of endogenous insulin on exocrine pancreatic secretion stimulated by a liquid meal as well as exogenous secretin and cholecystokinin octapeptide (CCK-8) in conscious rats.
(14) The subcellular distribution of sialyltransferase and its product of action, sialic acid, was investigated in the undifferentiated cells of the rat intestinal crypts and compared with the pattern observed in the differentiated cells present in the surface epithelium.
(15) We have investigated the increase in the spcDNA population upon cycloheximide treatment of individual sequences, which are found to amplify differentially.
(16) A phytochemical investigation of an ethanolic extract of the whole plant of Echites hirsuta (Apocynaceae) resulted in the isolation and identification of the flavonoids naringenin, aromadendrin (dihydrokaempferol), and kaempferol; the coumarin fraxetin; the triterpene ursolic acid; and the sterol glycoside sitosteryl glucoside.
(17) In the present investigation we monitored the incorporation of [14C] from [U-14C]glucose into various rat brain glycolytic intermediates of conscious and pentobarbital-anesthetized animals.
(18) Among the groups investigated, the subjects with gastric tumors presented the greatest values.
(19) Typological and archaeological investigations indicate that the church building represents originally the hospital facility for the lay brothers of the monastery, which according to the chronicle of the monastery was built in the beginning of the 14th century.
(20) Therefore, we have developed a powerful new microcomputer-based system which permits detailed investigations and evaluation of 3-D and 4-D (dynamic 3-D) biomedical images.