(1) Furthermore, comparison of these studies has revealed a differential dose response relationship between the number of graft lymphocytes, protection of engraftment, and induction of acute GVHD.
(2) Engraftment of donor cells was documented by HLA typing of peripheral lymphocytes.
(3) Glucose response to an arginine challenge was initially abnormal in both groups of mice, but was identical to normal controls 4 months after transplantation, showing that engraftment is a gradual process.
(4) Studies in severe combined immunodeficient mice that were engrafted with selected lymphocyte subpopulations show that B cells, and hence anti-Cryptococcus antibodies, are not necessary for the CD4+ T cell-dependent responses that isolate and subsequently destroy this opportunistic pathogen in the lung parenchyma.
(5) Marrow depleted of T cells exhibited reduced engraftment in the recipient fetuses.
(6) Treating bone marrow with MoAbs to myeloid differentiation antigens does not interfere with pluripotential stem cell engraftment.
(7) Prophylaxis by T cell depletion is associated with increased rates of engraftment failure and leukemic relapse.
(8) Posttransplant recovery was uneventful, and engraftment was comparable to that in 4 patients treated with a similar preparative regimen followed by infusion of autologous marrow.
(9) Ten dogs were given a combination of mAb 7.2 pregrafting and MTX after grafting, and 9 had evidence of engraftment.
(10) Three patients who received T-cell-depleted marrow cells from HLA-haploidentical donors failed to engraft and other graft failures were due to inadequate induction dosage.
(11) The in vivo use of an anti-CD11a-LFA-1 antibody as an additional immunosuppressive therapy in HLA-nonidentical BMT may thus promote engraftment and survival with correction of the primary disease in a significant number of patients with life-threatening immunodeficiency and osteopetrosis, but not with Fanconi's anemia.
(12) All four patients achieved quick engraftment, and three of the four patients are alive and well today.
(13) Engraftment has been sustained for one year and the patient is in normal health and has normal in vitro immunological function.
(14) Three of the seven surviving patients have durable engraftment (greater than 230 to greater than 550 days) while four patients have autologous hematopoietic recovery.
(15) All patients who failed to show engraftment or who rejected their bone marrow graft within three weeks had serum inhibitory to normal bone marrow cell culture, but inhibition could not be demonstrated against autologous bone marrow cells in these patients with aplastic anaemia.
(16) This study demonstrated that poor engraftment was a frequent complication of ABMT when early posttransplant cytotoxic therapy was attempted.
(17) The progressive disappearance of this autoreactivity was correlated with the engraftment of Ia-positive cells (monocytes plus B lymphocytes) of donor origin and the achievement of complete immunological reconstitution.
(18) Researchers are currently trying to reduce the RR by intensifying the conditioning regimen or using the graft-versus-leukemia effect of allogeneic T cells, reducing GvHD by the use of monoclonal antibodies, and improving the engraftment by the use of growth factors.
(19) The present work suggests that fetal liver infusion given following induction chemotherapy may increase the remission rate in AML either by temporary engraftment or by accelerating the rate of haematological recovery.
(20) These mice developed an active inflammatory myopathy beginning 15 days after engraftment.
Scion
Definition:
(n.) A shoot or sprout of a plant; a sucker.
(n.) A piece of a slender branch or twig cut for grafting.
(n.) Hence, a descendant; an heir; as, a scion of a royal stock.
Example Sentences:
(1) It was at this time that Milosevic forged a close friendship with Stambolic, scion of an elite communist family.
(2) State they’re in This was the season American MBNA credit-card scion Randy Lerner finally announced his Villa venture was over and he wanted to sell.
(3) Congress party strategists say that their campaign leader Rahul Gandhi 's relative youth – the scion of the Nehru-Gandhi dynasty is 43 – and their tradition of "pluralist secularism" will win over young people.
(4) Ineffectively led by the family scion Rahul, the party that won India its independence was comprehensively swept aside by Modi’s Bharatiya Janata party.
(5) Hall might be a scion of one of Britain's most important theatrical dynasties (his father is Peter, his half-sister Rebecca), but the cocky irreverence of his productions showed he had every intention of making his own mark.
(6) Two “prominent” Republicans told the New York Times that the scions of the respective affluent and well-connected white families will meet privately in Utah this week, not long before a Wall Street Journal reporter caught Bush at an airport gate for a flight headed to Salt Lake City, near where the Romney family keeps one of its largest houses .
(7) The judicial body confirmed establishing an indirect link with the elder Gaddafi scion, who is believed to be in southern Libya where he is attempting to reach either Niger or Mali.
(8) If it seems eccentric to compare Churchill, scion of the Dukes of Marlborough, with Davis, who was brought up in a council flat in south London, then factor in their shared attributes: unshakable self-confidence, a certain vanity, and a capacity to inspire affection and extreme irritation.
(9) Here, Visconti was doubly lucky; not only was he adapting a novel by Di Lampedusa, melancholic scion of a dwindled dynasty much like the one in The Leopard , but he himself – Luchino Visconti di Madrone, Count of Lonate Pozzolo – was himself such a figure, the playboy descendent of a powerful feudal family that had controlled Milan and Pisa before the Renaissance.
(10) It is particularly noteworthy that overrepresented in this list of political scions are southern Democrats , most of whom are also women.
(11) Unveiling his party's manifesto for elections beginning 7 April, Rahul Gandhi, the scion of the country's most famous political dynasty and the face of the Congress campaign for re-election , said $1tn (£600bn) would be spent on India's inadequate infrastructure and a universal pension scheme created if his party was returned to power.
(12) He mixed with an international circle of acquaintances, including politicians and scions of industry.
(13) John Gotti Junior, scion of the famous Gambino Mafia family, will walk into a Manhattan courtroom.
(14) But New England is overflowing with enough dynastic ambition right now to make even scions of the gilded age blush.
(15) He was born with, if not a silver spoon, then at least a silver-plated spoon in his mouth, being a scion on his father's side of the Kennedy earldom which used to own Culzean Castle in Scotland, and on his mother's side of a Scottish baronetcy.
(16) Money, connections and media attention can be a gift for a young scion seeking to outshine his or her famous parent, but they can also be a curse and some, like Jones, go to great lengths to avoid them.
(17) • Athinas Street, Mon-Sat 8am-6pm Nikos Hadjikyriakos-Ghika Gallery One of Greece’s most important 20th-century artists, Nikos Ghika was also a seriously minted scion of an aristocratic family (and a Rothschild by marriage) with exquisite taste in mid-century modern design.
(18) In controversial comments likely to cause a storm in India, Gandhi – considered a likely prime ministerial candidate and a scion of the country's leading political family – warned Timothy Roemer that although "there was evidence of some support for [Islamic terrorist group Laskar-e-Taiba] among certain elements in India's indigenous Muslim community, the bigger threat may be the growth of radicalised Hindu groups, which create religious tensions and political confrontations with the Muslim community ".
(19) The concept was exported to the US by Rorion Gracie, grandmaster of jiu jitsu , scion of one of the most famous fighting families in the world, and, as a 1989 article in Playboy put it, “the toughest man in the United States”.
(20) In the ensuing years – during which Hirsch was greeted by the American right as a prophet and a saviour, and by the left as a scion of the empire of evil – these ideas solidified.