(1) At saturating concentrations of ER, plasmids bearing one, two, and four EREs in tandem bound approximately one, two, and four dimeric ER molecules, respectively.
(2) Interestingly, each of these fragments had a perfect palindromic estrogen responsive element (ERE) (GGT-CANNNTGACC).
(3) These data suggest that flanking DNA sequences may exert a significant effect on the activity of EREs as hormone-dependent transcription activators.
(4) In 11 spontaneously breathing patients with chronic obstructive pulmonary disease (COPD) in acute ventilatory failure, we measured the total inspiratory (WItot) and total resistive (WI + Eres) work rate of breathing, together with lung mechanics (dynamic pulmonary elastance and inspiratory and expiratory pulmonary flow resistance).
(5) This element binds to the estrogen receptor in vitro as assessed by gel retardation assay similar to the vitellogenin gene ERE.
(6) The two polypeptides are different as judged by peptide mapping, and only the 85-kDa polypeptide can be cross-linked to the bromodeoxyuridine-substituted synthetic ERE by UV irradiation.
(7) Two methods have been suggested for the calculation of pHapp and the loss of activity on particle preparation, these methods are based on the use of the ERE in conjunction with experimental data.
(8) These results suggest that the ability of ER and TR to functionally discriminate between an ERE and a TRE is a result of dimerization of their DBDs.
(9) The presence of the biologically active hER is confirmed in co-injection experiments, in which HEO is co-introduced with a CAT reporter gene under the control of a vitellogenin promoter containing or lacking the ERE.
(10) Gene transfer experiments using estrogen-responsive cells have shown that the 13 bp perfect palindromic element GGTCACTGTGACC found upstream of the Xenopus laevis vitellogenin gene A2 promoter mediates hormonal stimulation and thus, was called the estrogen-responsive element (ERE).
(11) The ovalbumin promoter half-palindromic ERE motif located close to the TATA box was required for the activity of the distal DH3 ERE, but could be replaced by the binding sites of other transactivators.
(12) The equilibrium constant for the redox equilibration of fatty acid synthase in a glutathione redox buffer is 15 mM (Ered + GSSG in equilibrium Eox + 2GSH).
(13) When sequenced, these elements showed remarkable diversity and were different from the consensus vitellogenin A2 ERE.
(14) However at 32 degrees C Ta, there was an increase in rectal temperature in response to haloperidol application; this hyperthermia was due to a decrease in both the ear blood flow and respiratory evaporative heat loss (Eres).
(15) The affinity of estradiol binding to receptors was reduced only 2- and 5-fold, respectively, in the double and quadruple Cys to Ala mutants, and estradiol was an effective stimulator of transcription from an estrogen-responsive reporter gene [(ERE)2-TATA-CAT].
(16) A stimulatory estrogen response element (ERE) was localized to a 32-bp region between -547 and -516 bp.
(17) In these genes, two ERE homologues, which have only low, if any, regulatory capacity on their own, act synergistically to achieve high estrogen inducibility.
(18) "Gnnmph, I can't 'ave it 'ere, I 'aven't 'ad my enema," wails a labouring housewife, straining fruitlessly on a communal tenement bog as horrified neighbours look on in their rollers.
(19) This ERE also mediated down-regulation by progestins in the presence of the progesterone receptor, even though it has no progesterone receptor binding ability.
(20) This 67 bp region contains a consensus for the core sequence of the glucocorticoid responsive element (GRE) and the estrogen responsive element (ERE).
Erf
Definition:
(n.) A garden plot, usually about half an acre.
Example Sentences:
(1) The assumption that the distribution of pore sizes is Gaussian has led to the prediction of a linear relationship between the molecular Stokes radius (RS) of the protein and the function erf-1 (1-KD), where KD is the partition coefficient [Ackers (1967) J. Biol.
(2) In the present study, neuronal activities of retinal classes R2 and R3 and tectal classes T5(2) and T7 have been extracellularly recorded in response to leading and trailing edges of a 3 degrees X 30 degrees stripe simulating a worm and traversing the centers of their excitatory receptive fields (ERF) horizontally at a constant angular velocity in variable movement direction (temporo-nasal or naso-temporal).
(3) No significant difference was also shown in RBF between the control and all ERF-rats studied, through significant decreases in the renal clearance of NMN and renal extraction ratio (ER) were observed in the ERF-rats except the gentamicin-treated rats.
(4) The combination of Abc2, Abc1, and Erf also exhibited this activity.
(5) Overall cosmetic results were also better for the TRAM without implant than for the ERF (72% good vs. 51%).
(6) The accessory recombination function (arf) gene of bacteriophage P22 is located immediately upstream of the essential recombination function (erf) gene.
(7) After 1,25(OH)2D therapy a significant increase in serum phosphate, urinary calcium, and a decrease in urinary cAMP is observed only in ERF patients.
(8) However, Erf was inactive, both by itself and in combination with Abc1; Abc2 had weak activity.
(9) The red rod-mediated ERFs seem to be somewhat larger than the cone-mediated but smaller than the green rod-mediated.
(10) Greg Hunt spent his time in Paris continuing to pretend that his emissions reduction fund (ERF) is a carbon price and also an idea being adopted around the word, but the experts, when asked , said reverse auctions like the ERF were useful additions to a carbon price, but not a good primary policy to drive down greenhouse emissions.
(11) However, despite the smallest RFR, SK patients with ERF had the highest percentage increase in their GFR.
(12) Ten upper rectus (ERF) and 42 lower rectus (TRAM) were the two procedures applied.
(13) Nevertheless, the FMLC technique has been found to be a valid and useful technique particularly in the study of serum ERF titers.
(14) All three receptor types contribute to the IRF surrounding the ERF of classes 1, 2, 3 and deviating class 4 cells.
(15) Microsomal benzphetamine N-demethylase (BND) and 7-ethoxyresorufin O-deethylation (ERF) activities, catalyzed by P-450 isozymes 2 and 6, respectively, and specific P-450 content were determined after incubation with ABT.
(16) A correlation was noted between the magnitude of bronchial secretion viscosity and some characteristics: intensity of asphyxia attacks, dyspnea, number of dry rales; bronchial patency according to the ERF estimates.
(17) The pathophysiological consequence of such a deficiency in patients with ERF may be important.
(18) The nucleotide sequence of a segment of the bacteriophage P22 chromosome to the left (downstream in the PL operon) of the erf gene was determined.
(19) No significant difference was shown between the values of RBF determined by the NMN method and conventional p-aminohippurate (PAH) method in both the intact (control) and glycerol-ERF rats, suggesting the usefulness of the NMN method in determining RBF.
(20) On the basis of literature analysis and clinical experience, a classification of external respiratory failure (ERF) is suggested.